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[Animal Modeling - Pharmacological Evaluation] - Heterogeneic Animal In Situ Transplantation Bone Tumor Model

[Animal Modeling - Pharmacological Evaluation] - Heterogeneic Animal In Situ Transplantation Bone Tumor Model

Usually, tumor blocks or cells are implanted subcutaneously in nude mice, and the tumor continues to grow, simulating the process of human malignant tumor formation. The tumor formation rate is high, the tumor formation time is uniform, the tumor siz...

2024-07-18
[Animal Modeling Drug Efficacy Evaluation] - T-cell Transplantation Psoriasis Animal Model

[Animal Modeling Drug Efficacy Evaluation] - T-cell Transplantation Psoriasis Animal Model

Although the specific pathogenesis of psoriasis is not fully understood, the role of T lymphocytes in it is increasingly supported by evidence...

2024-07-18
[Animal Modeling - Pharmacological Evaluation] - Chemical Induced Brain Tumor Model

[Animal Modeling - Pharmacological Evaluation] - Chemical Induced Brain Tumor Model

Injecting some chemical carcinogens into different parts of animals in different ways can induce tumors, but the incidence, type, and location of tumors induced by carcinogens vary depending on their dosage, animal age, strain, and physiological stat...

2024-07-18
[Animal Modeling - Pharmacological Evaluation] - Corneal Injury Animal Model

[Animal Modeling - Pharmacological Evaluation] - Corneal Injury Animal Model

Corneal injury can be divided into damage to the corneal endothelium and damage to the corneal epithelium and stroma according to different levels...

2024-07-18
[Animal Modeling - Pharmacological Evaluation] - Corneal Neovascularization Animal Model

[Animal Modeling - Pharmacological Evaluation] - Corneal Neovascularization Animal Model

Corneal neovascularization often leads to a decrease in corneal transparency, which is an important cause of blindness and a high-risk factor for rejection reactions after corneal transplantation...

2024-07-18
[Animal Modeling - Efficacy Evaluation] - Dry Eye Disease Animal Model

[Animal Modeling - Efficacy Evaluation] - Dry Eye Disease Animal Model

Dry eye disease, also known as dry keratoconjunctivitis, is one of the most common eye diseases, which can cause damage to the ocular surface and blurred vision, affecting the quality of life of patients...

2024-07-18
[Animal Modeling - Pharmacological Evaluation ]- Animal Model of Retinal Disease Caused by Light Damage

[Animal Modeling - Pharmacological Evaluation ]- Animal Model of Retinal Disease Caused by Light Damage

At present, it is believed that retinal damage caused by strong light or continuous light exposure is influenced by species, region, diet, pre-treatment of light feeding history, and genetic background. One of the mechanisms of retinal oxidative ligh...

2024-07-18
[Animal Modeling - Pharmacological Evaluation]- Inducing Retinal Pigmentation Degeneration Animal Model

[Animal Modeling - Pharmacological Evaluation]- Inducing Retinal Pigmentation Degeneration Animal Model

Inducing retinal diseases involves the use of drugs or physical methods to alter the structure of the retina, resulting in conditions similar to human retinitis pigmentosa...

2024-07-18
[Animal Modeling - Pharmacological Evaluation] - Transgenic Pituitary Tumor Mouse Model

[Animal Modeling - Pharmacological Evaluation] - Transgenic Pituitary Tumor Mouse Model

FSH β - SV40T transgenic pituitary tumor mouse model...

2024-07-18
[Animal Modeling - Pharmacological Evaluation] - Ischemic Anemia Animal Model

[Animal Modeling - Pharmacological Evaluation] - Ischemic Anemia Animal Model

Hemolytic anemia is a common type of anemia, which refers to a type of anemia caused by the shortening and increasing destruction of red blood cells due to certain reasons, exceeding the compensatory capacity of the bone marrow. It is a common hemato...

2024-07-18
[Animal Modeling - Pharmacological Evaluation] - Blood Deficiency Syndrome Animal Model of Hemorrhagic Anemia and Malnutrition

[Animal Modeling - Pharmacological Evaluation] - Blood Deficiency Syndrome Animal Model of Hemorrhagic Anemia and Malnutrition

Adult rabbits were subjected to multiple blood draws from the central ear artery and femoral artery, once every other day, with an average of 8-10 ml per draw, not exceeding 10% of their total blood volume, for a period of 2 weeks. During this period...

2024-07-17
[Animal Modeling Drug Efficacy Evaluation ]- Rat Hindlimb Deep Venous Thrombosis Model

[Animal Modeling Drug Efficacy Evaluation ]- Rat Hindlimb Deep Venous Thrombosis Model

After intraperitoneal injection of sodium phenobarbital (75mg/kg) for anesthesia in the experimental group of SD rats, abdominal skin preparation was performed, and a midline incision was made through the abdominal white line to separate the lower en...

2024-07-17
[Animal Modeling - Pharmacological Evaluation] - Experimental Colitis Model in Young Rats

[Animal Modeling - Pharmacological Evaluation] - Experimental Colitis Model in Young Rats

Healthy male SD rats, 5-6 weeks old; Drug: 2,4,6-trinitrobenzenesulfonic acid (TNB)...

2024-07-17
[Animal modeling - Drug efficacy evaluation] - Repeated immunization induced ulcerative colitis in rats

[Animal modeling - Drug efficacy evaluation] - Repeated immunization induced ulcerative colitis in rats

Adult rats, male or female, weighing 250-400g; Medications: physiological saline, formaldehyde...

2024-07-17
【Animal Modeling - Pharmacological Evaluation】 - Gastric Administration of Alcohol Vinegar and Aspirin for Spleen Failure Blood Syndrome Animal Model

【Animal Modeling - Pharmacological Evaluation】 - Gastric Administration of Alcohol Vinegar and Aspirin for Spleen Failure Blood Syndrome Animal Model

Adult rats were given a dose of 50% medical ethanol 1ml/100g body weight by gavage on the first day, a dose of 1ml/100g body weight of Baoning vinegar by gavage from the 2nd to the 11th day, and a dose of 1% aspirin 1ml/100g body weight by gavage fro...

2024-07-17
[Animal modeling - Drug efficacy evaluation] - Non thoracotomy preparation of rabbit model of constrictive pericarditis

[Animal modeling - Drug efficacy evaluation] - Non thoracotomy preparation of rabbit model of constrictive pericarditis

New Zealand rabbits weighing 1.5-2.0kg were immobilized in a supine position and locally anesthetized with 2% procaine...

2024-07-16