[Animal modeling] - Animal experimental study on two different types of left atrial appendage occluders

To evaluate the feasibility and safety of left atrial appendage (LAA) closure with single disc cylindrical occluder and double disc split occluder...

2023-09-25

【Animal Modeling】-Establishment of a Drosophila Heart Failure Model Induced by High-fat Diet

To establish a model of Drosophila heart failure induced by high-fat diet...

2023-09-25

【Animal Modeling】 - Severe Combined Immunodeficiency Mouse Chronic Colitis Model

Female BALB/c mice (H-2 gene phenotype), aged 8-10 weeks at the time of use; Reagents and antibodies: Hamster anti mouse CD3 monoclonal antibody, fluorescein isothiocyanate labeled anti mouse CD45RB monoclonal antibody, phycoerythrin (PE) labeled ant...

2023-09-22

【 Animal modeling 】 -2,4,6-trinitrobenzene sulfonic acid induced ulcerative colitis model in rats

Animal modeling materials: 42 male SD rats, weighing (200 ± 20) g; Medication: 2,4,6-trinitrobenzenesulfonic acid...

2023-09-22

[Animal modeling] - Animal experimental evaluation on the safety pharmacology of Tanreqing injection

To observe the effects of Tanreqing injection on cardiovascular system, respiratory system of Beagle dogs and central nervous system of ICR mice, and to provide experimental data for its safety in clinical use...

2023-09-22

[Animal modeling] - Improvement and evaluation of conditions of rat model of myocardial hypertrophy induced by isoproterenol based on implantable osmotic pump

Myocardial hypertrophy is an effective compensatory function with slow development, an adaptive response to hemodynamics or myocardial injury, and an independent risk factor leading to heart failure...

2023-09-22

[Animal Modeling] - Animal Model of Lung Qi Deficiency Syndrome by Smoking Method

Adult rats or rabbits were placed in a smoke chamber with a volume of 1m3. 30-50g of shavings, sawdust, and tobacco were ignited and smoked once a day for 30 minutes each time. The smoking time of the rabbits was doubled, and their symptoms and signs...

2023-09-22

[Animal modeling] - Establishment, identification and preliminary phenotype of oligodendrocyte conditionally knockout FGF9 gene mouse model

To establish oligodendrocyte specific knockout fibroblast growth factor 9 (FGF9) mouse model and further study the role of FGF9 in neural development...

2023-09-22

【Animal modeling】-Establishment of acute and chronic hyperuricemia models

To establish acute mouse and chronic rat hyperuricemia models, and use positive drugs to verify the curability of the two models, so as to provide model tools for the development of anti-hyperuric acid drugs...

2023-09-22

【Animal Modeling】-Study on Periodic Lesion of Chronic Liver Injury in Mice

To study the characteristics of liver injury in a mouse model of chronic liver disease induced by carbon tetroxide (CCL4), and to explore its application in medical research...

2023-09-22

[Animal modeling] - protective effect of paeoniflorin on nerve injury in rats with acute cerebral infarction by activating LKB1/AMPK signal pathway

To investigate the protective effect of paeoniflorin on nerve injury in rats with acute cerebral infarction by activating hepatic kinase B1 (LKB1)/5 \\\'- adenosine phosphate activated protein kinase (AMPK) signal pathway...

2023-09-22

【Animal Modeling】-Effect of plantar shock stress duration on anxiety-like behavior in rats

To observe the effects of plantar shock stress duration on the elevated plus maze and anxiety-like behaviors in the opening test in rats...

2023-09-21

【Animal Modeling】-Radiation Pulmonary Fibrosis Model

Radiotherapy is one of the main treatment methods for breast tumors. Radiation pulmonary fibrosis is a common lung injury repair change after radiotherapy of breast tumors, which may lead to irreversible lung dysfunction...

2023-09-21

[animal modeling] - systematic evaluation of the effect of placental differentially expressed proteins on the growth and development of placenta in rat model of gestational diabetes

to systematically evaluate the effects of placenta differentially expressed proteins on the growth and development of placenta in diabetes of pregnancy (GDM) rat model...

2023-09-19

【Animal modeling】-5-Fluorouracil combined with mechanical scratching-induced oral mucositis model in golden hamsters

To establish a model of oral mucositis in golden hamsters induced by 5-fluorouracil combined with mechanical scratching...

2023-09-19

[Animal Modeling]-Effect of Curcumin on Rat Intestinal Mucosal Damage and Oxidative Stress in Desert Dry and Hot Environment

To explore the protective effect of curcumin pretreatment on rat intestinal mucosa in desert, dry and hot environments...

2023-09-19