![[Animal Modeling] - Immunomodulatory Factor Deficiency Mouse Model](/./uploads/images/default/default.png)
In B cell deficient Igh-6 gene knockout mice, homozygotes lack mature B cells and cannot express membrane bound IgM...
2023-10-09
rats; Medications: Anesthetics, antibiotics...
2023-10-09![[Animal Modeling] - Ulcerative Colitis in Rats](/./uploads/images/default/default.png)
SD rats, both male and female, weighing 200-250g; Medication: 5g/L soapy water, 20g/L pentobarbital, 50-100ml/L acetic acid solution, physiological saline; Instrument: 3mm diameter polyethylene fiber catheter...
2023-10-09![[Animal Modeling] - Reserpine Spleen Deficiency Syndrome Animal Model](/./uploads/images/default/default.png)
Adult rats were intramuscularly injected with reserpine at a dose of 0.2mg/kg body weight daily for three consecutive days; Adult rabbits were intramuscularly injected with reserpine at a dose of 0.3mg/kg body weight for three consecutive days. Obser...
2023-10-09![[Animal modeling] - Anti graft response induced ulcerative colitis in rats](/./uploads/images/default/default.png)
Animals: 5-6 month old rats, male and female, weighing 250-400g; Medication: pentobarbital...
2023-10-09![[Animal Modeling] - Severe Combined Immunodeficiency Mouse Chronic Colitis Model](/./uploads/images/default/default.png)
Female BALB/c mice (H-2 gene phenotype), aged 8-10 weeks at the time of use; Reagents and antibodies: Hamster anti mouse CD3 monoclonal antibody, fluorescein isothiocyanate labeled anti mouse CD45RB monoclonal antibody, phycoerythrin labeled anti mou...
2023-10-09![[Animal Modeling] - Experimental Colitis Model in Young Rats](/./uploads/images/default/default.png)
Healthy male SD rats, 5-6 weeks old; Drug: 2,4,6-trinitrobenzenesulfonic acid (TNB)...
2023-10-09![[Animal Modeling] - Animal Model of Lung Qi Deficiency Syndrome with Lipopolysaccharide and Smoking Method](/./uploads/images/default/default.png)
Adult rats were injected with lipopolysaccharide (LPS) 200 into the trachea on the 1st and 14th days, respectively μ G/200 μ L. On the 2nd to 13th and 15th to 28th mornings, smoke 5% cigarette smoke in a 72L fumigation box for 0.5 hours. Observe the ...
2023-10-09![[Animal Modeling] - Necrotizing Enterocolitis Model in Newborn Rats](/./uploads/images/default/default.png)
Animal: 1-day-old newborn Wistar rat offspring, male and female, weighing 5-10g...
2023-10-09
Wistar rats, male, weighing 120-140g; Medications: Methylnitrosoguanidine, Ranitidine...
2023-10-09
Adult rats were placed in a breeding cage, and their limbs were bound with a thin bandage to make it difficult to walk. The state of the rats was observed. After one week, changes in liver tissue, plasma malondialdehyde (MDA), liver tissue, and red b...
2023-10-09![[Animal Modeling] - Spontaneous Animal Model of Systemic Lupus Erythematosus](/./uploads/images/default/default.png)
This model is the earliest and most classic, as it produces NZB/W F1 generations through hybridization between the New Zealand Mouse Black strain (NZB) and the New Zealand Mouse White strain (NZW), which can develop into highly similar severe lupus l...
2023-10-09![[Animal Modeling] - Animal Model of Liver Qi Stagnation Syndrome Caused by Acute Irritation with Tail Clamping Method](/./uploads/images/default/default.png)
Adult rats were used to clamp one of the rats\' tails with a hemostatic forceps wrapped in gauze at the tip, causing it to tear and beat with other rats, indirectly provoking the entire cage of rats. Indirect provoking rats were used as experimental ...
2023-10-09![[Animal Modeling] - Systemic Lupus Erythematosus Induced Model](/./uploads/images/default/default.png)
The drug lupus model commonly uses a high concentration of isopentadiene type alkane - pristane - enriched in mineral oil, and intraperitoneal injection of pristane is a standard method for obtaining enriched monoclonal antibody ascites...
2023-10-09
Model making material animal: China No.1 small pig; Medication: Helicobacter pylori strain...
2023-10-09
There are three common types: squamous skin mutant mice, spontaneous chronic proliferative dermatitis mutant mice, and sebum deficient mutant mice...
2023-10-09