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【Animal modeling】-Protective effect of curcumin on renal fibrosis in 5/6 kidney ligation-induced chronic kidney disease mouse model

【Animal modeling】-Protective effect of curcumin on renal fibrosis in 5/6 kidney ligation-induced chronic kidney disease mouse model

To study the protective effect of curcumin on renal fibrosis in chronic kidney disease, and to explore the possible mechanism of action...

2022-11-30
【Animal modeling】-Establishment of reference values of lymphocyte subsets in BALB/c mice, SD rats and cynomolgus monkeys

【Animal modeling】-Establishment of reference values of lymphocyte subsets in BALB/c mice, SD rats and cynomolgus monkeys

To collect the determination results of peripheral blood lymphocyte subsets completed by the National Center for Drug Safety Evaluation and Monitoring from 2007 to 2019 under the conditions of quality management of drug non-clinical research, and to...

2022-11-30
【Animal modeling】-Protective effect of aerobic exercise combined with paeonol PLGA nanoparticles on obese rats with hyperlipidemia

【Animal modeling】-Protective effect of aerobic exercise combined with paeonol PLGA nanoparticles on obese rats with hyperlipidemia

To investigate the effect of aerobic exercise combined with paeonol PLGA nanoparticles on blood biochemistry and lipid metabolism in obese rats with hyperlipidemia...

2022-11-30
【Animal modeling】-Based on the LIGHT/HVEM pathway to study the protective effect of resveratrol on renal injury in preeclamptic rats

【Animal modeling】-Based on the LIGHT/HVEM pathway to study the protective effect of resveratrol on renal injury in preeclamptic rats

To investigate the effect of resveratrol (RSV) on the lymphotoxin analog (LIGHT)/herpesvirus intervening body (HVEM) pathway in preeclampsia (PE) rats, and its protective effect on renal injury...

2022-11-29
Animal modeling] - camouflage technology inspired by cephalopod skin cells

Animal modeling] - camouflage technology inspired by cephalopod skin cells

A study found that combining a temperature-sensitive dye on a thin, flexible electrical substrate with a distributed light sensor could lead to systems that have the ability to automatically adapt to match the color of their surroundings, as a way fr...

2022-11-29
【Animal modeling】The effect of -13-methyltetradecanoic acid on abnormal oxygen in rat cerebral cortex astrocytes

【Animal modeling】The effect of -13-methyltetradecanoic acid on abnormal oxygen in rat cerebral cortex astrocytes

To study the protective effect of 13-methyltetradecanoic acid on abnormal oxygen in rat cerebral cortical astrocytes...

2022-11-29
【Animal modeling】-Optimization of in vivo chromosomal aberration test in ICR mice

【Animal modeling】-Optimization of in vivo chromosomal aberration test in ICR mice

To conduct in vivo chromosomal aberration experiments in ICR mice, by administering cyclophosphamide and colchicine at different time points, to compare the effects of different administration/collection time points and different administration conce...

2022-11-29
【Animal Modeling】-Relationship between the expression of related splicing factors and the inclusion rate of SMN2 exon 7 in SMA mice

【Animal Modeling】-Relationship between the expression of related splicing factors and the inclusion rate of SMN2 exon 7 in SMA mice

To study the inclusion of SMN2 exon 7 in different tissues of SMA mice, and to screen the related splicing factors...

2022-11-29
【Animal Modeling】-The effect of icariin on experimental IgA nephropathy in rats and related mechanisms

【Animal Modeling】-The effect of icariin on experimental IgA nephropathy in rats and related mechanisms

To explore the effects of different doses of icariin on rats with experimental IgA nephropathy, and to study its related mechanism...

2022-11-29
【Animal Modeling】-A Preliminary Study on the Localization of Microinjection in the Nucleus Solitarius of Rats

【Animal Modeling】-A Preliminary Study on the Localization of Microinjection in the Nucleus Solitarius of Rats

To explore the localization method of microinjection in the nucleus tractus solitarius of rats by applying different parameters of localization injection to improve the success rate and accuracy of injection...

2022-11-29
【Animal modeling】-FGF-2/PELA/BMP-2 microcapsule scaffold promotes the osteogenic differentiation of rat periosteum-derived stem cells

【Animal modeling】-FGF-2/PELA/BMP-2 microcapsule scaffold promotes the osteogenic differentiation of rat periosteum-derived stem cells

To observe the effect of fibroblast growth factor-2/polylactic acid-polyethylene glycol-polylactic acid/bone morphogenetic protein-2 (FGF-2/PELA/BMP-2) microcapsule scaffold on the formation of periosteum-derived stem cells in SD rats. Bone different...

2022-11-28
【Animal modeling】-Preparation and preliminary identification of rabbit anti-marmoset IgG-HRP-labeled antibody

【Animal modeling】-Preparation and preliminary identification of rabbit anti-marmoset IgG-HRP-labeled antibody

To purify IgG antibody from marmoset serum, prepare rabbit anti-marmoset antiserum, and purify IgG from antiserum, HRP (horseradish peroxidase)-labeled rabbit anti-marmoset IgG...

2022-11-28
【Animal Modeling】-Establishment of an in vitro culture system of adult marmoset kidney cells and the application of CRISPR/Cas9 gene editing

【Animal Modeling】-Establishment of an in vitro culture system of adult marmoset kidney cells and the application of CRISPR/Cas9 gene editing

To establish a culture system for in vitro culture of adult marmoset kidney cells, and to initially apply the Cas9 editing system to the cultured marmoset kidney cells to establish a system for detecting sgRNA cleavage activity...

2022-11-28
【Animal modeling】-Effect of PM2.5 on reproductive endocrine level and pregnancy outcome in female mice

【Animal modeling】-Effect of PM2.5 on reproductive endocrine level and pregnancy outcome in female mice

To study the effects of PM2.5 on reproductive endocrine hormone levels and pregnancy outcomes in female rats...

2022-11-28
【Animal Modeling】-Albino C57BL/6N Mice Made by CRISPR-Cas9 Knockout of Tyr Gene

【Animal Modeling】-Albino C57BL/6N Mice Made by CRISPR-Cas9 Knockout of Tyr Gene

To obtain albino C57BL/6N mice and expand their application in skin transplantation and embryonic stem cell research...

2022-11-28
【Animal modeling】-3M tissue glue and electrocoagulation for hemostasis in nephrectomy in uremic rats

【Animal modeling】-3M tissue glue and electrocoagulation for hemostasis in nephrectomy in uremic rats

To compare the application of two hemostatic methods in rat uremic model...

2022-11-28