[Animal modeling] - Improvement and evaluation of conditions of rat model of myocardial hypertrophy induced by isoproterenol based on implantable osmotic pump

Myocardial hypertrophy is an effective compensatory function with slow development, an adaptive response to hemodynamics or myocardial injury, and an independent risk factor leading to heart failure...

2022-12-06

[Animal modeling] - The effect of compound rehmannia granules on the regulation of serum cyclic nucleotides and the repair of dopaminergic neurons in Parkinson\'s disease mice with yin deficiency and

To investigate the effect of compound rehmannia granules on the regulation of serum cyclic nucleotides and the repair of dopamine neurons in Parkinson\'s disease mice with yin deficiency and wind movement syndrome...

2022-12-06

[Animal modeling] - Effect of arginine vasopressin 1b receptor knockout on anxiety and social behavior of female rats

to investigate the effects of arginine vasopressin 1b receptor gene knockout on plasma corticosterone content, anxiety and social behavior in female rats...

2022-12-06

[Animal modeling] - Comparison of effects of different exercise modes on MSTN and IGF1 of skeletal muscle in rats

To explore the effects of different exercise modes on MSTN and IGF1 of skeletal muscle in rats, and to provide theoretical basis for selecting appropriate exercise modes to improve skeletal muscle function...

2022-12-06

[Animal modeling] Neuroprotective effect of soybean saponin Bb preconditioning on cerebral ischemia reperfusion model rats

To investigate the neuroprotective effect of soybean saponin Bb preconditioning on cerebral ischemia/reperfusion in rats...

2022-12-06

[Animal modeling] - endoplasmic reticulum stress - mitochondrial autophagy pathway in rat pulmonary hypertension

To investigate the role of endoplasmic reticulum stress mitochondrial autophagy pathway in pulmonary hypertension induced by monocrotaline in rats...

2022-12-05

[Animal modeling] - Study on the mechanism of Herba Siegesbeckiae Tongshuan Capsule in alleviating cognitive function damage in rats with chronic cerebral ischemia

To study the effect of Siegesbeck Tongshuan capsule on the rat model of chronic cerebral ischemia and blood brain barrier...

2022-12-05

[Animal modeling] - Based on 16S rRNA sequencing, analyze the effects of two reoviruses on intestinal flora of mice

To investigate the effects of T1L and NBV reovirus on intestinal flora in mice...

2022-12-02

[Animal modeling] Effect of low expression of lipoic acid synthase on antioxidant capacity of mice

To establish a genetically modified mouse with low expression of lipoic acid synthase gene and detect its antioxidant capacity...

2022-12-02

[Animal modeling] - Transcriptome analysis of colon tissue in IBD mice under the intervention of mesalazine

To detect the changes of gene expression in colon tissue of mice with inflammatory bowel disease (IBD) by transcriptome sequencing, and to improve the understanding of the molecular mechanism of mesalazine in the treatment of IBD...

2022-12-02

[Animal modeling] - Study on the effect and mechanism of Bushen Yiqi Huayu Granule on angiogenesis in ovariectomized osteoporosis model rats

Based on TLRs/NF- κ Study on the Effect of Bushen Yiqi Huayu Granule on Angiogenesis in Osteoporosis Rats by B Signal Pathway...

2022-12-02

[Animal modeling] - Based on autophagy, explore the effect of fentanyl combined with propofol on myocardial ischemia-reperfusion injury in rats

To investigate the effect of fentanyl combined with propofol on myocardial ischemia-reperfusion injury in rats based on autophagy...

2022-12-02

[Animal modeling] - The regulatory effect of curcumin and/or aerobic exercise on intestinal function in rats with dyslipidemia

To investigate the effects of curcumin and/or aerobic exercise on intestinal function in dyslipidemic rats...

2022-12-02

[Animal modeling] - Effect of macrophage MED1 deletion on blood glucose level and insulin resistance in mice

To study the role of macrophage MED1 in the regulation of insulin resistance...

2022-12-02

[Animal modeling] - Effect of compound microecological preparation on intestinal immune function of mice

To study the effect of compound microecological preparation on intestinal mucosal immune function in mice...

2022-12-02

[Animal modeling] - Protective effect of Dahuang Mudan decoction on liver injury in rats with acute pancreatitis

To investigate the protective effect of Dahuang Mudan decoction on liver injury in rats with acute pancreatitis...

2022-12-02