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[Animal modeling] - Establishment of acute gouty arthritis rat model and observation of model maintenance time

[Animal modeling] - Establishment of acute gouty arthritis rat model and observation of model maintenance time

To establish a rat model of acute gouty arthritis and observe its maintenance time...

2023-02-17
【Animal Modeling】-Screening and application of single nucleotide polymorphism markers for identification of four commonly used strains of rats

【Animal Modeling】-Screening and application of single nucleotide polymorphism markers for identification of four commonly used strains of rats

To screen out the single nucleosides that can rapidly identify four commonly used rat strains [Wistar rat, Goto-Kakizaki (GK) rat, Brown-Norway (BN) rat, Sprague-Dawley (SD) rat] Acid polymorphism (single nucleotide polymorphism, SNP) site and verify...

2023-02-17
【Animal Modeling】-Study finds first evidence of rapid changes in primate fur pigmentation

【Animal Modeling】-Study finds first evidence of rapid changes in primate fur pigmentation

Chameleons and squid can change their colors, but monkeys can\\\'t—until humans step in. Researchers found that a normally black long-haired howler monkey in Costa Rica began to develop distinctive yellow patches on its tail and legs...

2023-02-17
【Animal modeling】-The role and mechanism of eNOS/NO pathway in renal interstitial microangiopathy in mice with unilateral ureteral obstruction

【Animal modeling】-The role and mechanism of eNOS/NO pathway in renal interstitial microangiopathy in mice with unilateral ureteral obstruction

To investigate the role and mechanism of endothelial nitric oxide synthase and nitric oxide in microvascular disease in mice with unilateral ureteral obstruction and renal interstitial fibrosis...

2023-02-17
【Animal modeling】-Micro-CT observation of the effect of recombinant human parathyroid hormone on fracture healing in 2-month-old male rats

【Animal modeling】-Micro-CT observation of the effect of recombinant human parathyroid hormone on fracture healing in 2-month-old male rats

To investigate the effect of recombinant human parathyroid hormone (rhPTH) on fracture healing in 2-month-old male rats using Micro-CT...

2023-02-16
【Animal modeling】-Effects of estrogen and progesterone on the differential expression of αvβ3 induced by bovine endometrial epithelial cells in vitro

【Animal modeling】-Effects of estrogen and progesterone on the differential expression of αvβ3 induced by bovine endometrial epithelial cells in vitro

To study the changes of integrin αvβ3 gene induced differential expression in bovine uterine epithelial cells cultured in vitro, in order to provide reference for exploring the marker proteins of bovine uterine receptivity...

2023-02-16
【Animal Modeling】-Effect of Feilongzhi blood extract on inflammatory factors in hyperlipidemia rats with myocardial ischemia

【Animal Modeling】-Effect of Feilongzhi blood extract on inflammatory factors in hyperlipidemia rats with myocardial ischemia

To observe the effect of the blood extract of Feilongzhi on inflammatory factors in hyperlipidemia rats with myocardial ischemia, and to preliminarily explore the mechanism of TAE on cardiovascular protection...

2023-02-16
[Animal modeling] - Study on the safety and effectiveness of human umbilical cord mesenchymal stem cells in the treatment of acute lung injury in mice

[Animal modeling] - Study on the safety and effectiveness of human umbilical cord mesenchymal stem cells in the treatment of acute lung injury in mice

To investigate the safety and efficacy of human umbilical cord mesenchymal stem cells (HUC-MSCs) in the treatment of lipopolysaccharide (LPS) - induced acute lung injury in mice...

2023-02-15
[Animal modeling] - Experimental study on the colonization of two strains of CRISPR engineered Escherichia coli in mice

[Animal modeling] - Experimental study on the colonization of two strains of CRISPR engineered Escherichia coli in mice

To evaluate the colonization ability and efficiency of two Escherichia coli engineering strains, Nissle1917 and BW25113, in the intestinal tract by using mice, so as to screen out the strains with high colonization efficiency in the intestinal tract,...

2023-02-15
【Animal Modeling】-Effects of Noise Pollution on Blood Hormone and Hsp-70 Levels in Rats

【Animal Modeling】-Effects of Noise Pollution on Blood Hormone and Hsp-70 Levels in Rats

To investigate the effects of noise pollution on blood hormone levels and expression of heat shock protein-70 (Hsp-70) in rats...

2023-02-14
【Animal Modeling】-Analysis of the application of asthma animal model based on data mining

【Animal Modeling】-Analysis of the application of asthma animal model based on data mining

To analyze the modeling elements of asthma animal models, and to provide methodological reference for improving the success rate of modeling and evaluating the tested drugs effectively...

2023-02-14
【Animal modeling】-Study on the protective effect of Ginkgo biloba extract on MPTP-induced Parkinson\\

【Animal modeling】-Study on the protective effect of Ginkgo biloba extract on MPTP-induced Parkinson\\

To observe the preventive effect of Ginkgo biloba extract on 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)-induced Parkinson\\\'s mice of different ages...

2023-02-14
【Animal Modeling】-Effect of Bushen Yangxue Recipe on Anti-Müllerian Hormone in Rats with Premature Ovarian Failure

【Animal Modeling】-Effect of Bushen Yangxue Recipe on Anti-Müllerian Hormone in Rats with Premature Ovarian Failure

To establish a rat model of premature ovarian failure induced by Tripterygium wilfordii polyglycosides, and to study the effect of Bushen Yangxue Recipe on anti-mullerian in rats with premature ovarian failure...

2023-02-14
【Animal Modeling】-Screening reference genes with different expression abundances using expression profile chip data

【Animal Modeling】-Screening reference genes with different expression abundances using expression profile chip data

Based on the detection results of expression profiling chip, multiple reference genes were screened for quantitative detection of genes with different expression abundances in the liver tissue of Mus musculus...

2023-02-13
【Animal modeling】-miR-144 negatively regulates the expression of TOLL-like receptor 2 in rat macrophages

【Animal modeling】-miR-144 negatively regulates the expression of TOLL-like receptor 2 in rat macrophages

To clarify the relationship between TOLL-like receptor 2 (TLR2) and the role of microRNA144 (miR-144)...

2023-02-13
[Animal modeling] - Study on the effect of dexmedetomidine combined with sufentanil on pulmonary ischemia-reperfusion injury in rats

[Animal modeling] - Study on the effect of dexmedetomidine combined with sufentanil on pulmonary ischemia-reperfusion injury in rats

To investigate the effect of dexmedetomidine combined with sufentanil on pulmonary ischemia-reperfusion injury (LIRI) in rats...

2023-02-09