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【Animal Modeling】-Expression of Perilipin in Kidney Tissue of Rats with Diabetic Nephropathy

【Animal Modeling】-Expression of Perilipin in Kidney Tissue of Rats with Diabetic Nephropathy

To observe the characteristics of rat diabetic nephropathy model and the diagnostic value of urinary LN for early DN, and to explore the expression of perilipin in the kidney of DN rats...

2023-02-22
【Animal modeling】-In vitro differentiation of mouse umbilical cord mesenchymal stem cells

【Animal modeling】-In vitro differentiation of mouse umbilical cord mesenchymal stem cells

To isolate and expand mouse umbilical cord mesenchymal stem cells to investigate whether they can be induced into cartilage, adipose and osteoblasts...

2023-02-22
【Animal modeling】-Effect of Tempol on NF-κB signaling pathway in myocardial hypertrophy rats

【Animal modeling】-Effect of Tempol on NF-κB signaling pathway in myocardial hypertrophy rats

To investigate the effect of 2, 2, 6, 6-tetramethyl-4-piperidinol (temPol) on NF-κB signaling pathway in rat cardiac hypertrophy?...

2023-02-22
[Animal Modeling]-Spinal Cord Contusion Model

[Animal Modeling]-Spinal Cord Contusion Model

Spinal cord contusion (contusion injury) was proposed by Allen by copying the spinal cord contusion model using weight loss methods. The specific method is to use a heavy hammer of a specific mass to drop vertically along a series of tubes and hit a...

2023-02-22
【Animal modeling】-Comparative study on steroid hormone synthesis ability of mice with drug-induced deficiency syndrome induced by cisplatin continuous and interval modeling

【Animal modeling】-Comparative study on steroid hormone synthesis ability of mice with drug-induced deficiency syndrome induced by cisplatin continuous and interval modeling

To study the effect of different dosage regimens of cisplatin on steroid hormone synthesis and reserve function in mice...

2023-02-21
【Animal modeling】-Effect of postconditioning with dezocine on acute lung injury induced by intestinal ischemia-reperfusion in rats

【Animal modeling】-Effect of postconditioning with dezocine on acute lung injury induced by intestinal ischemia-reperfusion in rats

To investigate the effect and possible mechanism of dezocine postconditioning on acute lung injury induced by intestinal ischemia-reperfusion in rats...

2023-02-21
【Animal modeling】-Analysis of the localization and expression of vitamin D receptor in the duodenum of C57BL/6 mice

【Animal modeling】-Analysis of the localization and expression of vitamin D receptor in the duodenum of C57BL/6 mice

To investigate the localization and expression of vitamin D receptors in the duodenum of C57BL/6 mice, and to study the correlation between vitamin D system and intestinal development...

2023-02-21
【Animal modeling】-Application of three mouse enterovirus nucleic acid detection technologies in mouse health monitoring

【Animal modeling】-Application of three mouse enterovirus nucleic acid detection technologies in mouse health monitoring

To use nucleic acid detection technology to detect MHV, Reo-3 and MNV enteroviruses in cecal contents of mice, and to compare the results with serological detection results to analyze the applicability of nucleic acid detection in mouse health monito...

2023-02-21
【Animal modeling】-Evaluation of mouse renal ischemia-reperfusion injury by combining ultrasound radiation force with targeted ultrasound microbubbles

【Animal modeling】-Evaluation of mouse renal ischemia-reperfusion injury by combining ultrasound radiation force with targeted ultrasound microbubbles

  Study ultrasound radiation to promote the adhesion of target microbubbles and improve the sensitivity and feasibility of renal ischemia-reperfusion injury detection...

2023-02-21
【Animal modeling】-5-Fluorouracil-induced mouse model of chemotherapy-induced intestinal mucositis

【Animal modeling】-5-Fluorouracil-induced mouse model of chemotherapy-induced intestinal mucositis

To study the 5-fluorouracil-induced mouse model of chemotherapy-induced intestinal mucositis...

2023-02-21
【Animal Modeling】-Establishment and evaluation of pancreatic cancer orthotopic transplantation model based on clinical surgical specimens

【Animal Modeling】-Establishment and evaluation of pancreatic cancer orthotopic transplantation model based on clinical surgical specimens

To establish an orthotopic transplantation model of pancreatic cancer based on clinical tumor specimens, and to carry out model evaluation research...

2023-02-20
【Animal Modeling】-Effect of icariin on androgen receptor signaling pathway in orthotopic prostate cancer xenografts in SCID mice

【Animal Modeling】-Effect of icariin on androgen receptor signaling pathway in orthotopic prostate cancer xenografts in SCID mice

To observe the effect of icariin on androgen receptor signaling pathway in orthotopic xenografts of prostate cancer in SCID mice...

2023-02-20
【Animal modeling】-Isolation, culture and identification of hepatic stellate cells in gerbils

【Animal modeling】-Isolation, culture and identification of hepatic stellate cells in gerbils

To explore a stable and economical method for the isolation and culture of hepatic stellate cells in gerbils, and to provide technical support for the in-depth study of the cellular mechanism of hepatic fibrosis in gerbils...

2023-02-20
【Animal Modeling】-Inhibition of PAR2-PKA/PKCε pathway in peripheral neurons affects pain threshold in rats with pain transformation

【Animal Modeling】-Inhibition of PAR2-PKA/PKCε pathway in peripheral neurons affects pain threshold in rats with pain transformation

To investigate the role of peripheral neuron protease-activated receptor 2-protein kinase A/protein kinase Cε (PAR2-PKA/PKCε) pathway in pain transformation, and to find a possible solution to simultaneously intervene in acute pain and chronic pain...

2023-02-20
【Animal Modeling】-Systematic evaluation of the effect of musical stimulation on the brain function of offspring mice

【Animal Modeling】-Systematic evaluation of the effect of musical stimulation on the brain function of offspring mice

To systematically evaluate the effect of musical stimulation on the brain function of offspring rats, and to provide a scientific basis for promoting the welfare of experimental animals and the application and development of musical prenatal educatio...

2023-02-20
【Animal Modeling】-Comparison of morphological characteristics of liver tissue between four commonly used experimental animals and humans

【Animal Modeling】-Comparison of morphological characteristics of liver tissue between four commonly used experimental animals and humans

By comparing the similarities in histology and morphology between the livers of four commonly used experimental animals, mice, rats, guinea pigs, and rabbits, and human livers, it provides a reference for the selection of experimental animals in live...

2023-02-17