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【Animal modeling】-nicotine inhibits MIA-induced apoptosis of rat osteoarthritis chondrocytes

【Animal modeling】-nicotine inhibits MIA-induced apoptosis of rat osteoarthritis chondrocytes

To investigate the inhibition of nicotine on the apoptosis of osteoarthritis chondrocytes induced by sodium iodoacetate (MIA)...

2023-03-04
【Animal Modeling】-A single intraosseous injection of simvastatin promotes normalization of tumor blood vessels in mouse breast cancer

【Animal Modeling】-A single intraosseous injection of simvastatin promotes normalization of tumor blood vessels in mouse breast cancer

To study the effect of a single intraosseous injection of simvastatin on the vascular structure and function of mouse breast cancer tumors...

2023-03-04
【Animal modeling】-Isolation, culture and identification of goat alveolar macrophages

【Animal modeling】-Isolation, culture and identification of goat alveolar macrophages

To establish a high-purity method for isolating and culturing alveolar macrophages to provide materials for studying the biological characteristics of macrophages and the survival mechanism of intracellular parasites...

2023-03-04
【Animal modeling】-Effect of perfluorooctane sulfonate on rat embryonic development and placental IGF-1 expression

【Animal modeling】-Effect of perfluorooctane sulfonate on rat embryonic development and placental IGF-1 expression

To investigate the effects of different doses of perfluorooctane sulfonate exposure on embryonic development and placental insulin-like growth factor-1 expression in rats...

2023-03-04
【Animal modeling】-Effect of Jiuxieling granules on the expression of TLR4 and NF-κB p65 in rats with ulcerative colitis of spleen and kidney yang deficiency

【Animal modeling】-Effect of Jiuxieling granules on the expression of TLR4 and NF-κB p65 in rats with ulcerative colitis of spleen and kidney yang deficiency

To investigate the effect of Jiuxieling Granules on the expression of TLR4 and NF-κB p65 protein genes in colon tissue of rats with ulcerative colitis due to spleen and kidney yang deficiency...

2023-03-04
【Animal Modeling】-Effects of different samples and methods on the determination of blood biochemical indexes in rats

【Animal Modeling】-Effects of different samples and methods on the determination of blood biochemical indexes in rats

To compare the effects of two different samples of serum and plasma and different test methods on the measured values of blood biochemical indexes and blood glucose in rats...

2023-03-04
【Animal Modeling】-Effect of first mating age on reproductive performance of NIH mice

【Animal Modeling】-Effect of first mating age on reproductive performance of NIH mice

To systematically study the effects of different first mating days on the reproductive performance of NIH mice...

2023-03-04
【Animal Modeling】-Optimization of the detection method of Pasteurella pneumophila in mice and drug purification of infected mice

【Animal Modeling】-Optimization of the detection method of Pasteurella pneumophila in mice and drug purification of infected mice

To optimize the detection method of Pasteurella pneumophila in mice, improve the detection sensitivity to strengthen the daily monitoring of Pasteurella pneumophila, and explore the feasibility of drug purification in infected mice...

2023-03-04
【Animal Modeling】-Analysis of Bacterial Community Diversity in Large Intestine Contents of Tree Shrews

【Animal Modeling】-Analysis of Bacterial Community Diversity in Large Intestine Contents of Tree Shrews

To analyze the structure and composition of E. coli bacteria in tree shrew by high-throughput sequencing technology...

2023-03-04
【Animal modeling】-Effect of percutaneous electrical stimulation on end-to-side anastomosis of peripheral nerves in rats

【Animal modeling】-Effect of percutaneous electrical stimulation on end-to-side anastomosis of peripheral nerves in rats

To observe and explore the effect of percutaneous electrical stimulation on nerve regeneration after nerve end-to-side anastomosis and its clinical value...

2023-03-03
Early mouse embryonic stem cell models are more accurate

Early mouse embryonic stem cell models are more accurate

Scientists at the Hub Hubrecht Institute (KNAW) and Cambridge University (UK) have successfully produced complex embryo-like structures from mouse embryonic stem cells. These structures, called gastric colloids, allow the ovaries to grow for the firs...

2023-03-03
【Animal Modeling】-Ultrasonic radiation force combined with targeted ultrasound microbubbles to evaluate renal ischemia-reperfusion injury in mice

【Animal Modeling】-Ultrasonic radiation force combined with targeted ultrasound microbubbles to evaluate renal ischemia-reperfusion injury in mice

To investigate the sensitivity and feasibility of ultrasonic radiation force to promote the adhesion of targeted microbubbles to improve the detection of renal ischemia-reperfusion injury...

2023-03-02
【Animal modeling】-Effect of paclitaxel on the expression of CD28, CTLA-4 and BAFF in experimental autoimmune encephalomyelitis rats

【Animal modeling】-Effect of paclitaxel on the expression of CD28, CTLA-4 and BAFF in experimental autoimmune encephalomyelitis rats

To investigate the effect of paclitaxel on the expression of CD28 and CTLA-4 in the brain tissue of rats with experimental autoimmune encephalomyelitis and the content of B cell stimulating factor (BAFF) in the supernatant of spleen tissue and its si...

2023-03-02
【Animal Modeling】-Analysis of the correlation between intestinal flora characteristics of tree shrew and high-grade sarcoma based on 16S rRNA sequencing

【Animal Modeling】-Analysis of the correlation between intestinal flora characteristics of tree shrew and high-grade sarcoma based on 16S rRNA sequencing

To detect the gut microbiota structure of tree shrew with high-grade sarcoma, and to provide a scientific basis for exploring the correlation between changes in gut microbiota structure and tumorigenesis...

2023-03-02
[Animal Modeling]-Pathological observation of spontaneous tumors in old SD rats

[Animal Modeling]-Pathological observation of spontaneous tumors in old SD rats

Observe the development of spontaneous tumors in SD rats and provide background information for the development of new drugs on carcinogenicity research...

2023-03-02
【Animal Modeling】-Differential expression of miRNA in myocardial tissue of endotoxemia rats

【Animal Modeling】-Differential expression of miRNA in myocardial tissue of endotoxemia rats

To analyze the changes of miRNA expression profile in myocardial tissue of endotoxin, also known as lipopolysaccharide rats, and to explore the role of miRNA in endotoxemia myocardial injury...

2023-03-01