[Animal modeling] - Application analysis of asthma animal model based on data mining

To analyze the modeling factors of asthma animal models, and to provide methodological reference for improving the success rate of modeling and effectively evaluating the tested drugs...

2022-11-02

[Animal modeling] - Infection of TNF by Listeria monocytogenes α Establishment and application of humanized mouse model

To evaluate TNF ⁃ α Susceptibility of host to listeria monocytogenes infection after intervention of monoclonal antibody...

2022-11-02

[Animal modeling] - Study on the regulatory effect and mechanism of silencing miRNA-16 on immune function of pulmonary tuberculosis model mice

To study the regulatory effect of silent miR-16 on immune function of pulmonary tuberculosis model mice and its mechanism...

2022-11-02

[Animal modeling] Experimental observation on evaluation points of blood glucose intervention in type 2 diabetes mouse model

To observe the changes of blood glucose in type 2 diabetes mouse model, and explore the feasibility of blood glucose 2 hours after meal as a blood glucose intervention evaluation point...

2022-11-02

[Animal modeling] - Analysis of magnetic resonance spectroscopy and ultrastructure in hippocampus of APP/PS1 double transgenic AD model mice

To observe the relationship between the changes of metabolites in the hippocampus of APP/PS1 transgenic mice and the ultrastructural pathological changes, so that the APP/PS1 transgenic mice can be better used in the experimental study of Alzheimer\'...

2022-11-02

[Animal modeling] - Study on the regulatory effect of tacrolimus on spinal cord injury model rats based on NF kB/JNK signal pathway

To investigate the therapeutic effect of tacrolimus on spinal cord injury in rats and its regulation on NF kB/JNK signal pathway...

2022-11-02

[Animal modeling] - Evaluation and research progress of common behavior paradigms in the model of mother infant separation

As an important way of early social deprivation, separation of mother and infant has always been a classic animal model to study the adverse effects of early life stress on individual physiology and psychology...

2022-11-02

[Animal modeling] - Construction of a nude mouse model of clear cell renal cell carcinoma and study on its targeted drug sensitivity

To establish a tumor animal model with clear cell renal cancer cells from patients, and to detect the sensitivity of ccRCC PDCs to molecular targeted drugs, so as to provide theoretical and experimental basis for clinical diagnosis and treatment...

2022-11-02

[Animal modeling] - Comparative study on establishing allergic conjunctivitis model in mice under different conditions

To establish allergic conjunctivitis mouse models under different antigens, different excitation pathways and different mouse weeks, and to screen the best sensitization conditions by comparing the immune response status, so as to provide new ideas a...

2022-11-02

[Animal modeling] - Preparation of chronic myocardial ischemia model in mice induced by different doses of isoproterenol and establishment of evaluation criteria

To establish the model of chronic myocardial ischemia in mice by subcutaneous injection of different doses of isoproterenol (ISO) into the neck, and to determine the best dose of the model through comparison, so as to seek more objective and reliable...

2022-11-02

[Animal modeling] - Establishment and analysis of hyperlipidemia cynomolgus monkey model

To establish the model of hyperlipidemia cynomolgus monkey...

2022-11-02

[Animal modeling] - Preparation and evaluation of rat model of cognitive impairment after brain injury

To explore the preparation and evaluation of an animal model of cognitive impairment after brain injury...

2022-11-02

[Animal modeling] - Establishment of rat model of hyperuricemia and its complications

To establish a stable and efficient rat model of hyperuricemia with liver and kidney injury, gouty arthritis and other complications...

2022-11-02

[Animal modeling] - Evaluation of the therapeutic effect of Fenbid on the rat model of lumbar disc herniation

To study the effect of fenbid, a cyclooxygenase inhibitor, on lumbar disc herniation...

2022-11-02

[Animal modeling] - Comparative study on animal models of Graves disease in mice and monkeys

Based on the immune related mechanism of Graves disease, this study aims to explore the characteristics of different animal GD models by comparing the mouse and macaque GD animal models in our previous studies, and provide research tools for future i...

2022-11-02

[Animal modeling] Comparative study on pulmonary fibrosis models induced by bleomycin and endotoxin in two strains of mice

To compare the degree of pulmonary fibrosis induced by bleomycin and endotoxin in ICR and C57BL/6 mice, so as to establish a suitable model of pulmonary fibrosis in mice...

2022-11-02