[Animal modeling] - Establishment of drug addiction model of mental dependence and expression of Bax gene in cerebellum

To study the effect of heroin on the expression of Bax gene in the cerebellum of addictive rats...

2022-11-02

[Animal modeling] - Characteristics of cardiac structure, function and pathological process of pressure overload heart failure mouse model

to establish a mouse heart failure model and evaluate the characteristic changes of cardiac function and structure in the course of disease development by ultrasonic imaging and pathological techniques...

2022-11-02

[Animal modeling] - LPS induced inflammation model of fibroblast like synoviocytes in knee joint of SD rats and its characteristics

To establish the primary culture method of normal knee synovial cells in Sprague Dawley (SD) rats and the inflammation model of fibroblast like synovial cells induced by lipopolysaccharide...

2022-11-02

[Animal modeling] - Comparative study of three types of extrahepatic cholestasis models in rats

To evaluate the advantages and disadvantages of three surgical models of extrahepatic cholestasis in rats by serology, imaging and pathology...

2022-11-02

[Animal modeling] - Establishment of a mouse model of lung metastasis and recurrence after bone marrow injection

to establish the model of lung metastasis and postoperative recurrence by bone marrow injection, and to reveal the superiority and feasibility of bone marrow injection model, so as to provide a new research basis for the study of lung metastasis of m...

2022-11-02

[Animal modeling] - Study on the mechanism of jujuboside in alleviating Alzheimer\'s disease model mice

To investigate the mechanism of jujuboside (ZSS) in alleviating sevoflurane anesthesia in 9-month-old APP/PS1/tau transgenic mice with Alzheimer disease...

2022-11-02

[Animal modeling] - Experimental study on establishing rat obesity model with high calorie diet

To observe the effect of establishing rat obesity model with high calorie diet, and the difference between the two kinds of rats, and compare different obesity evaluation methods and obesity sensitive animal screening methods, so as to provide refere...

2022-11-01

[Animal modeling] - Construction and application of an improved rat skull defect animal model

To explore the ideal method of constructing rat skull defect model and improve the success rate of bone defect animal model...

2022-11-01

[Animal modeling] - Comparative study on the construction of high altitude pulmonary edema model in SD rats under different hypoxia stress

To study the effects of different hypoxia stress modes on the establishment of high altitude pulmonary edema model...

2022-11-01

[Animal modeling] - Establishment of premature ovarian failure model induced by chemotherapy in rats by intraperitoneal injection of different doses of cisplatin

To explore the method of establishing the model of chemotherapy-induced premature ovarian failure in rats by intraperitoneal injection of different doses of cisplatin (CP)...

2022-11-01

[Animal modeling] - Establishment of a mouse model of chronic thrombosis induced by carrageenan

To screen the conditions of chronic thrombosis model in mice by continuous intraperitoneal injection of carrageenan solution with different concentrations...

2022-11-01

[Animal modeling] - establish an animal model of human intestinal flora of Alzheimer\'s disease

To obtain a mouse model of human intestinal flora of Alzheimer\'s disease by oral fecal bacteria transplantation, and evaluate the model by bioinformatics, histopathology and other methods...

2022-11-01

[Animal modeling] - Application analysis of 274 rheumatoid arthritis animal models based on data mining

To study the modeling factors of rheumatoid arthritis animal models, and provide methodological reference for improving the success rate of modeling and evaluating the effectiveness of tested drugs...

2022-11-01

[Animal modeling] Establishment of ulcerative colitis model in mice by different administration methods of dextran sodium sulfate

To study the model of ulcerative colitis in mice after intragastric administration or free drinking of dextran sodium sulfate...

2022-11-01

[Animal modeling] - Preliminary establishment of rat transplantation model of human glioma

To establish a rat model of human glioma xenotransplantation using immunosuppressants, and to provide an ideal experimental tool for clinical and basic research...

2022-11-01

[Animal modeling] - Establishment of chronic hyperuricemia kidney damage rat model

To establish a rat model of chronic hyperuricemia induced renal damage, and to provide a model tool for drug development against chronic hyperuricemia induced renal damage...

2022-11-01