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【Animal Modeling】-The influence of multiple knee joint defects

【Animal Modeling】-The influence of multiple knee joint defects

Since articular cartilage does not heal naturally, there is no cure for methods that can regenerate hyaline cartilage in a consistent and predictable manner. Some recognized cartilage repair methods include minimally invasive (MFX) and matrix-induced...

2022-10-24
【Animal modeling】-Effects of epithelial sodium channels on osteoclast differentiation and bone resorption in rats

【Animal modeling】-Effects of epithelial sodium channels on osteoclast differentiation and bone resorption in rats

This article investigates the effect of epithelial sodium channel (ENaC) on the function and activity of osteoclasts...

2022-10-22
【Animal Modeling】-Effect of endometriosis on the fertility of mice

【Animal Modeling】-Effect of endometriosis on the fertility of mice

To establish a mouse model of endometriosis, and to observe the effect of endometriosis on the pregnancy ability of the model mice...

2022-10-22
【Animal modeling】-Nude mouse prostate cancer metastasis model

【Animal modeling】-Nude mouse prostate cancer metastasis model

Even after transplantation due to immunodeficiency, nude mice that have undergone human tumor xenotransplantation also grow well. The morphological and functional characteristics of human tumors transplanted into nude mice are basically the same as t...

2022-10-22
【Animal Modeling】-Establishment and preliminary application of multiplex PCR method for Staphylococcus aureus, Pseudomonas aeruginosa and Klebsiella pneumoniae

【Animal Modeling】-Establishment and preliminary application of multiplex PCR method for Staphylococcus aureus, Pseudomonas aeruginosa and Klebsiella pneumoniae

To establish a multiplex PCR detection method for Staphylococcus aureus, Pseudomonas aeruginosa and Klebsiella pneumoniae, and to provide a rapid, sensitive and simple method for bacterial detection in experimental animals...

2022-10-22
【Animal modeling】-Comparison of calcium chelated collagen polypeptide and estrogen on bone improvement in ovariectomized rats

【Animal modeling】-Comparison of calcium chelated collagen polypeptide and estrogen on bone improvement in ovariectomized rats

To compare the bone-improving effect of calcium chelated collagen polypeptide (CPCC) with that of estrogen, and to lay a foundation for the research and development of safe osteoporosis prevention and treatment drugs...

2022-10-22
【Animal modeling】-Effect of short needling method on the expression of Sox9, VEGF and ColⅩ in rabbit knee osteoarthritis chondrocytes

【Animal modeling】-Effect of short needling method on the expression of Sox9, VEGF and ColⅩ in rabbit knee osteoarthritis chondrocytes

To observe the effect of short needling method on the expression of sex-determining region (Sox9), vascular endothelial cell growth factor (VEGF) and type X collagen (ColⅩ) in articular chondrocytes of rabbit knee osteoarthritis (KOA) articular carti...

2022-10-22
【Animal Modeling】-Other congenital heart disease models in miniature pigs

【Animal Modeling】-Other congenital heart disease models in miniature pigs

Guerreiro et al. established a model of growing pig myocardial hypertrophy using surgical methods. The experiment used 4-month-old pigs to establish aortic-pulmonary shunt through surgery, and then reared to 7 months of age. 4 weeks after surgery, pu...

2022-10-22
【Animal Modeling】-Expression of AQP1 and AQP5 in the Respiratory Membrane of Rats with Acute Lung Injury

【Animal Modeling】-Expression of AQP1 and AQP5 in the Respiratory Membrane of Rats with Acute Lung Injury

To determine whether the aquaporins AQP1 and AQP5 are expressed in the alveolar capillary membrane (respiratory membrane) of rats, and then to study the expression regulation of AQP1 and AQP5 in rats with acute lung injury (ALI) and the effect of hor...

2022-10-22
【Animal Modeling】-Animal Model of Endometrial Cancer

【Animal Modeling】-Animal Model of Endometrial Cancer

Endometrial carcinoma (endometrial carcinoma), also known as uterine corpus cancer, originates from the endometrium epithelium. It is one of the three major malignant tumors of the female reproductive tract, accounting for about 7% of the total numbe...

2022-10-22
[Animal Modeling]-Effect of Feilong Palm Blood Extract on Inflammatory Factors in Hyperlipidemia Rats with Myocardial Ischemia

[Animal Modeling]-Effect of Feilong Palm Blood Extract on Inflammatory Factors in Hyperlipidemia Rats with Myocardial Ischemia

Observe the effect of TAE on inflammatory factors in rats with hyperlipidemia and myocardial ischemia, and preliminarily explore the protective effect of TAE on cardiovascular...

2022-10-22
【Animal modeling】-Effect of N-acetylcysteine on hepatic oxidative stress and FoxO1 activity in type 2 diabetic rats

【Animal modeling】-Effect of N-acetylcysteine on hepatic oxidative stress and FoxO1 activity in type 2 diabetic rats

To investigate the effect of antioxidant N-acetylcysteine on hepatic oxidative stress and FoxO1 activity in type 2 diabetic rats...

2022-10-22
【Animal modeling】-Analysis of microsatellite DNA genetic diversity in specific pathogen-free Jinding duck

【Animal modeling】-Analysis of microsatellite DNA genetic diversity in specific pathogen-free Jinding duck

To analyze the genetic diversity of specific pathogen-free Jinding duck population using microsatellite markers...

2022-10-22
【Animal modeling】-Inhibitory effect of low-frequency electroacupuncture on DRG P2X3 receptors in rats with type 2 diabetic neuralgia

【Animal modeling】-Inhibitory effect of low-frequency electroacupuncture on DRG P2X3 receptors in rats with type 2 diabetic neuralgia

To observe the effect of low-frequency electroacupuncture on the pain threshold and the expression of P2X3 receptors in the L5 dorsal root ganglia in type 2 diabetic neuralgia model rats...

2022-10-22
【Animal modeling】-Establishment of multiplex detection method of serological liquid chip technology for common infectious diseases in transgenic mice

【Animal modeling】-Establishment of multiplex detection method of serological liquid chip technology for common infectious diseases in transgenic mice

To prepare mouse MHV, LCM, ECT and HANT liquid-phase chips, and to establish an xMAP multiplex detection method for infectious disease antibodies in transgenic mice...

2022-10-22
【Animal Modeling】-Effect of androgen deficiency on mRNA alternative splicing in high-fat and high-cholesterol-fed minipigs

【Animal Modeling】-Effect of androgen deficiency on mRNA alternative splicing in high-fat and high-cholesterol-fed minipigs

To explore the effect of androgen deficiency on the effects of androgen deficiency on high-fat and high-cholesterol diets by analyzing the liver expression profiles of non-castrated (SHAM), castrated (CAS) and castrated+testosterone-treated (CAS+T) m...

2022-10-22