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![[Animal Modeling]-Lateral hydraulic shock brain injury model](/./uploads/images/default/default.png)
The lateral hydraulic shock brain injury model involves the rapid injection of a certain amount of normal saline into the cranial cavity, causing deformation and displacement of the brain tissue...
2022-02-02Pancreatic cancer is a highly malignant tumor with a poor prognosis. Pancreatic cancer is insidious, difficult to diagnose early, and is prone to liver metastasis, peritoneal spread or local recurrence, and insensitivity to chemotherapy drugs...
2022-02-02The researchers transplanted human liver cells into immunodeficient mice and allowed them to grow in the mice, gradually forming a human-mouse chimeric liver. In this animal model, HBV can survive in human liver cells and be humanized, mouse hepatiti...
2022-02-02Acetaldehyde is an intermediate metabolite of ethanol, which directly damages the liver and converts coenzyme I (NAD) into reduced coenzyme I (NADH) in the liver, thereby reducing the ratio of NAD/NADH. It inhibits the tricarboxylic acid cycle, and t...
2022-02-02Methionine-choline deficiency (MCD) diets are commonly used to induce classic NAFLD animal models. MCD diet is rich in carbohydrates (40%) and fat (10%), but lacks methionine and choline, which are involved in the oxidation of fatty acid β in liver c...
2022-02-02The benchmark behavior evaluation of the learning and memory abilities of rodent AD models was mainly tested in the Morris water maze experimental system....
2022-02-02Kawai\\\'s test method is to create a 30 cm x 30 cm x 15 cm plexiglass box with a 6 cm x 6 cm grid engraved on the bottom, and test in a quiet low light environment. After allowing the animal to adapt to the environment for 10 minutes, calculate the ...
2022-02-02With the development of the transportation and construction industry, the emergence of accidents and natural disasters, the incidence of traumatic brain injury (TBI) is gradually increasing. Traumatic brain injury ranks first among the causes of deat...
2022-02-02Liver cancer model formed by transplanting animal or human liver cancer tissues, cell lines and other malignant tumors into animals...
2022-02-02ApoE- can create ob/ob mice + MCD diet, db/db mice + MCD diet, Abcb11 mice + MCD diet and other animal models by combining genetic modification and nutritional factors according to the rules of human NAFLD. /-Mouse + HFD, PPARa-/-mouse + MCD diet, et...
2022-02-02Key gene mutations in fat metabolism in liver cells can cause abnormal fat metabolism and disrupt the balance of fat input/output in the liver...
2022-02-02Generally, methylnitrosonitroguanidine (N-methyl-N\\\'-nitrosonitroguanidine, MNNG) and methylcholestene (MC) are used. MNNG is a kind of polycyclic hydrocarbon, which has a strong carcinogenic effect and can cause the production of nitric oxide in t...
2022-02-02Every year, many Chinese patients suffer serious sequelae, such as paralysis caused by SCI. How to regenerate nerve cells and nerve fibers after spinal cord injury and how much function is restored are very important issues...
2022-02-02Hepatitis E is mainly transmitted through the fecal-oral route (digestive tract), and other routes include blood transmission and vertical transmission. Taking advantage of the transmission characteristics of hepatitis E, the method of intravenously...
2022-02-02In order to reduce the occurrence of accidents, it is necessary to limit the number of people who can enter the laboratory at the same time...
2022-02-02Understand the basic principles and replication methods of the rat pulmonary edema model...
2022-02-02