[Animal Modeling]-Establishment and evaluation methods of other drug dependent animal models

The method of ketamine (commonly known as K powder) is a non-competitive N-methyl-D-aspartate receptor antagonist and has an anesthetic effect. It is widely used in clinical medicine, especially in pediatric patients and the heart Among sick patients...

2022-02-02

【Animal Modeling】-Nude mice orthotopic vaccination model of human gastric cancer

The proliferation, metastasis and recurrence of gastric cancer depend on angiogenic factors. There are many factors affecting the transplantation of human gastric cancer into nude mice, including human gastric cancer tissue and cells transplanted int...

2022-02-01

【Animal Modeling】-Hydroxyethyl Starch 40 Sodium Chloride Injection Allergy Experimental Study

To evaluate the safety of allergy to hydroxyethyl starch 40 sodium chloride injection...

2022-02-01

【Animal Modeling】-The establishment of a mouse model of erlotinib-induced skin adverse reactions

Erlotinib is a new type of targeted drug for the treatment of non-small cell lung cancer. In recent years, it has been widely used in clinical practice, but it has many side effects. Among them, rash is the most common and most difficult for patients...

2022-02-01

The protective effect of anesthesia on the establishment of a rat model of severe trauma and hemorrhagic shock

Establish a modified rat model of severe trauma and hemorrhagic shock to explore the protective effect of anesthesia on the establishment of STHS rat model...

2022-02-01

【Animal Modeling】-How to establish a nude mouse model of human prostate cancer xenograft?

Establish a human-derived xenograft (PDX) model of prostate cancer and evaluate the anti-tumor efficacy of various treatment options?...

2022-02-01

【Animal Modeling】-Determination of Microbial Diversity of Common Cotton-eared Marmoset Manure Based on High-throughput Sequencing Technology

Apply high-throughput sequencing technology to analyze the structure and composition of the fecal flora of common cotton-eared marmoset monkeys, and lay the foundation for the further development and utilization of new experimental animals...

2022-02-01

[Animal Modeling]-Hemorrhoids Magnetizing Ointment to Mouse Model of Hemorrhoids

To study the protective effect of hemorrhoids magnetic ointment on mice with hemorrhoids induced by acetic acid...

2022-02-01

【Animal Modeling】-Effect of alcohol exposure during pregnancy on basic rhythmic respiratory discharge in medulla oblongata of newborn rats

To investigate the effect of alcohol exposure during pregnancy on basic rhythmic respiratory discharge activity (RRDA) in the medulla oblongata slices of offspring of newborn rats...

2022-02-01

Skin stem cells cultivated human 【mini】hearts, which will replace animal experiments in the future

American scientists have genetically recombined pluripotent stem cells extracted from human skin and cultivated a microventricle with human heart cells...

2022-02-01

【Animal Modeling】-The effect of estrogen and progesterone on the induced differential expression of αvβ3 in bovine endometrial epithelial cells in vitro

To study the changes in the induced differential expression of integrin αvβ3 gene in bovine uterine epithelial cells cultured in vitro, in order to provide a reference for exploring the marker protein of bovine uterine receptivity?...

2022-02-01

【Animal Modeling】-Hr gene knockout mouse model construction and phenotype analysis

Establishment of knockout mice for detailed study of the function of hairless genes (Hr)...

2022-02-01

【Animal Modeling】-Preliminary Study on the Effect of Lipopolysaccharide on Naked Mole Lung Tissue

To observe and analyze the effects of lipopolysaccharide on the morphological structure and pathological indexes of naked mole rats’ lung tissues, and to preliminarily explore whether the naked mole rats are resistant to LPS...

2022-02-01

【Animal Modeling】-Lentivirus-mediated shRNA targeting survivin gene inhibits the growth of endometrium in the abdominal cavity of nude mice

To study the effect of lentivirus-mediated survivin gene specific short hairpin RNA (shRNA) on the growth of human endometrium implanted in the abdominal cavity of nude mice...

2022-02-01

【Animal Modeling】-What is the source tumor tissue xenograft model?

The tumor transplantation model established by transplanting the patient\\\\\\\'s tumor tissue into immunodeficient mice retains the biological characteristics of the primary tumor, but the matrix components of the tumor tissue are passaged in the mi...

2022-02-01

【Animal Modeling】-Small Ubiquitin-like Modifier Protease 3 Regulates Autophagy in Mouse Alveolar Type Ⅱ Epithelial Cells

To investigate the regulatory effect and molecular mechanism of small ubiquitin-like modifier-specific protease 3 on autophagy in mouse lung tissue cells...

2022-02-01