[Animal Modeling - Efficacy Evaluation] - Transgenic Animal Models

The model is mainly established using genetically modified technology...

2024-08-21

[Animal Modeling - Pharmacological Evaluation] - Rat Cerebral Vasospasm Model

The replication method used to create a DCV model in rats after subarachnoid hemorrhage by inserting a catheter through the frontal subarachnoid space and injecting blood twice directly into the Willis circle of the cerebral artery...

2024-08-21

[Animal Modeling - Pharmacological Evaluation] - Mouse Cerebral Vasospasm Model

The replication of SAH was anesthetized by intraperitoneal injection of pentobarbital sodium (60mg/kg body weight), and the skin in the surgical area was disinfected...

2024-08-21

[Animal Modeling - Pharmacological Evaluation] - Canine Intracranial Hypertension Model

Healthy domestic dogs, weighing 10-20kg. Anesthesia with intravenous injection of pentobarbital sodium at a dose of 30mg/kg body weight...

2024-08-21

[Animal Modeling - Pharmacological Evaluation] - Rabbit Intracranial Hypertension Model

New Zealand rabbits, male or female, weighing 2.0-2.5kg. After intravenous injection of pentobarbital sodium (at a dose of 25-30mg/kg body weight) or 20% Uratan (at a dose of 5ml/kg body weight) through the ear vein, anesthesia was administered. The ...

2024-08-21

[Animal Modeling - Pharmacological Evaluation] - Brain Hematoma Animal Model

The evolution of cerebral hematoma is a very complex process, and it is often difficult to conduct systematic research on this process from a clinical perspective...

2024-08-21

[Animal Modeling - Pharmacological Evaluation]- Venous Thrombosis Animal Model

Venous thrombosis is closely related to slow blood flow, increased coagulation factor activity, and vascular wall damage. Therefore, experimental models of venous thrombosis can be formed by methods such as ligation of veins, interruption or obstruct...

2024-08-21

[Animal Modeling - Pharmacological Evaluation] - Animal Model of Cerebral Arteriovenous Malformation

The previous animal models of cerebral arteriovenous malformations were arteriovenous fistulas without a true malformation mass structure. Massoud et al. established for the first time in 1994 an animal model of cerebral arteriovenous malformation co...

2024-08-21

[Animal Modeling - Pharmacological Evaluation] - Brain Ischemic Tolerance Animal Model

The phenomenon of cerebral ischemic tolerance refers to the pre production of sublethal ischemia in the brain. This increases the tolerance of brain neurons to subsequent lethal ischemia, thereby preventing the occurrence of delayed neuronal death af...

2024-08-21

【Animal modeling - Drug efficacy evaluation】 - Focal nephritis model

dog; Medications: Pentobarbital, hot water, turpentine...

2024-08-21

[Animal Modeling - Pharmacological Evaluation] - Animal Model of Kidney and Kidney Yang Deficiency Syndrome Caused by Labor Injury

Take male mice as the modeling objects and induce \"atrioventricular node\" in healthy estrus female mice...

2024-08-20

[Animal modeling - Drug efficacy evaluation] - Alcohol induced acute liver injury model

Animals: rats weighing 200-250g, or mice weighing 25-30g, male or female not limited; Medicine: 56 degree Baijiu...

2024-08-20

【Animal Modeling - Pharmacological Evaluation】- Application of Sex Hormones in Kidney Yang Deficiency Animal Model

Select female rat pups born during the same period of selective mating, and inject testosterone propionate subcutaneously into the neck and back of 8-day-old female rats at a dose of 1.25mg/animal. Wean at 22 days of age...

2024-08-20

【nimal modeling - Efficacy evaluation】 - Acute liver injury model induced by carbon tetrachloride

rats weighing 200-250g, or mice weighing 20-25g, regardless of gender; Drug: Carbon tetrachloride (CCl4)...

2024-08-20

[Animal Modeling Drug Efficacy Evaluation]- Histone Phosphate Induced Peptic Ulcer Model

rats, weighing 180-260g; Drug: Histamine phosphate...

2024-08-20

[Animal Modeling - Pharmacological Evaluation] - Stress Induced Peptic Ulcer Model

Male SD rats, 14 weeks old, weighing 150-200g; Medication: Ether, 1% formaldehyde solution...

2024-08-20