[Animal Modeling - Pharmacological Evaluation] - Preparation of Cerebral Ischemia Model in Rats with Autologous Thrombosis Combined with Thread Thrombosis Blocking the Middle Cerebral Artery

SD rats, 2-3 months old, half male and half female, with an average weight of (300 ± 50) g; Medications: Chloral hydrate, thrombin...

2024-07-29

[Animal modeling - Drug efficacy evaluation ]- Preparation of influenza virus infection secondary pneumococcal pneumonia model

In the ranking of human disease mortality rates, bacterial pneumonia and influenza rank sixth. Animal models can be used to study the mechanism of interaction between influenza and pneumococcal bacteria...

2024-07-29

[Animal Modeling - Pharmacological Evaluation] - In vivo Thrombosis Animal Model

Wistar rats, male or female, weighing 200-250g; Medications: Ethyl carbamate, heparin injection; Equipment: Disposable intravenous catheter, BL-420 biological function experimental system...

2024-07-29

[Animal Modeling - Pharmacological Evaluation] - Coronary Artery Quantitative Stenosis and Blood Stasis Syndrome Animal Model

Adult experimental dogs were anesthetized and underwent positive pressure artificial respiration with endotracheal intubation. The fifth rib of the left chest was incised, a heart bag was cut, and a pericardial bed was made. The coronary artery was s...

2024-07-29

[Animal Modeling - Pharmacological Evaluation] - Low Selenium Mouse Model of Viral myocarditis

Selenium was discovered over 180 years ago, initially for its toxic effects on the liver. Later, it was found that selenium is essential for the growth of animals and humans at low concentrations, and toxic at high concentrations...

2024-07-29

Animal Modeling Drug Efficacy Evaluation Reflux Gastritis Model

Male rats weighing 200-250g; Medications: Pentobarbital, physiological saline, iodine...

2024-07-29

Animal Modeling Drug Efficacy Evaluation Autoimmune Antibody Passive Transport Model

IgG was taken from patients with bullous pemphigoid (BP) and injected into the cornea of New Zealand rabbits. After 24 hours, epidermal separation, thickening, and blister formation appeared on the cornea. The inflammatory response is dose-dependent,...

2024-07-29

[Animal modeling - Drug efficacy evaluation] - Dry knot constipation model

Healthy Kunming mice, weighing (30 ± 2) g, both male and female...

2024-07-29

[Animal Modeling - Pharmacological Evaluation] - Comprehensive Stimulation Method of Wind Cold and Sulfur Dioxide for Lung Qi Deficiency Animal Model

Adult rats were stimulated with sulfur dioxide at a dose of (200-250) × 10 ^ -5, for 1 hour per day for 13 days. Wind cold stimulation was performed using cold air at a temperature 5 ℃ lower than the living environment temperature of the rats for 15 ...

2024-07-29

[Animal Modeling Drug Efficacy Evaluation ]- Severe Combined Immunodeficiency Mouse Chronic Colitis Model

Female BALB/c mice (H-2 gene phenotype), aged 8-10 weeks at the time of use; Reagents and antibodies: hamster anti mouse CD3 monoclonal antibody, fluorescein isothiocyanate (FITC) labeled anti mouse CD45RB monoclonal antibody, phycoerythrin (PE) labe...

2024-07-29

[Animal Modeling Drug Efficacy Evaluation] - Establishment of Rat Ulcerative Colitis Model by Immune Compound Method

Healthy Wistar rats, half male and half female, weighing approximately 200g; Healthy rabbits; Drug: Complete Freund\'s adjuvant, formaldehyde solution...

2024-07-29

[Animal Modeling Drug Efficacy Evaluation] - Animal Model of Hyperthyroidism with Kidney Yin Deficiency Syndrome

Adult rats were orally administered thyroid hormone at a dose of 2.5mg/kg body weight per day for 3 weeks. The changes in body weight, water intake, urine output, pain threshold, heart rate, etc. before and after modeling were routinely measured. At ...

2024-07-29

[Animal Modeling - Pharmacological Evaluation] - Adrenal Cortical Hyperactivity and Kidney Yin Deficiency Animal Model

Adult mice were subcutaneously injected with hydrocortisone at a dose of 1mg per mouse, once every other day, for a total of three times. Detect relevant indicators of fatigue resistance test, cold resistance test, hypoxia resistance test, carbon par...

2024-07-29

[Animal Modeling - Pharmacological Evaluation] - Animal Model of Hypertension with Kidney Yin Deficiency Syndrome

Adult rats were subjected to nephrectomy on one side and ligation of 2/3 of the renal artery on the other side. Blood pressure in the tail artery of the rats was measured 2 weeks after surgery, and those with systolic blood pressure>140mmHg (18.6k...

2024-07-29

[Animal Modeling - Pharmacological Evaluation ]- Animal Model of Kidney and Kidney Yang Deficiency Syndrome Caused by Labor Injury

Take male mice as the modeling objects and induce \"atrioventricular node\" in healthy estrus female mice...

2024-07-29

[Animal Modeling - Pharmacological Evaluation ]- Congenital Kidney Yang Deficiency Syndrome Animal Model

Adult mice, good at calling fierce cats. When raising mice to 75 days of age, they were mated in a 2:1 ratio between males and females. On the evening of the 4th day, male mice were taken out, and on the 5th day, the experimental mice were threatened...

2024-07-29