[Animal Modeling - Pharmacological Evaluation ]- Animal Model of Retinal Disease Caused by Light Damage

At present, it is believed that retinal damage caused by strong light or continuous light exposure is influenced by species, region, diet, pre-treatment of light feeding history, and genetic background. One of the mechanisms of retinal oxidative ligh...

2024-07-18

[Animal Modeling - Pharmacological Evaluation]- Inducing Retinal Pigmentation Degeneration Animal Model

Inducing retinal diseases involves the use of drugs or physical methods to alter the structure of the retina, resulting in conditions similar to human retinitis pigmentosa...

2024-07-18

[Animal Modeling - Pharmacological Evaluation] - Transgenic Pituitary Tumor Mouse Model

FSH β - SV40T transgenic pituitary tumor mouse model...

2024-07-18

[Animal Modeling - Pharmacological Evaluation] - Ischemic Anemia Animal Model

Hemolytic anemia is a common type of anemia, which refers to a type of anemia caused by the shortening and increasing destruction of red blood cells due to certain reasons, exceeding the compensatory capacity of the bone marrow. It is a common hemato...

2024-07-18

[Animal Modeling - Pharmacological Evaluation] - Blood Deficiency Syndrome Animal Model of Hemorrhagic Anemia and Malnutrition

Adult rabbits were subjected to multiple blood draws from the central ear artery and femoral artery, once every other day, with an average of 8-10 ml per draw, not exceeding 10% of their total blood volume, for a period of 2 weeks. During this period...

2024-07-17

[Animal Modeling Drug Efficacy Evaluation ]- Rat Hindlimb Deep Venous Thrombosis Model

After intraperitoneal injection of sodium phenobarbital (75mg/kg) for anesthesia in the experimental group of SD rats, abdominal skin preparation was performed, and a midline incision was made through the abdominal white line to separate the lower en...

2024-07-17

[Animal Modeling - Pharmacological Evaluation] - Experimental Colitis Model in Young Rats

Healthy male SD rats, 5-6 weeks old; Drug: 2,4,6-trinitrobenzenesulfonic acid (TNB)...

2024-07-17

[Animal modeling - Drug efficacy evaluation] - Repeated immunization induced ulcerative colitis in rats

Adult rats, male or female, weighing 250-400g; Medications: physiological saline, formaldehyde...

2024-07-17

【Animal Modeling - Pharmacological Evaluation】 - Gastric Administration of Alcohol Vinegar and Aspirin for Spleen Failure Blood Syndrome Animal Model

Adult rats were given a dose of 50% medical ethanol 1ml/100g body weight by gavage on the first day, a dose of 1ml/100g body weight of Baoning vinegar by gavage from the 2nd to the 11th day, and a dose of 1% aspirin 1ml/100g body weight by gavage fro...

2024-07-17

[Animal modeling - Drug efficacy evaluation] - Non thoracotomy preparation of rabbit model of constrictive pericarditis

New Zealand rabbits weighing 1.5-2.0kg were immobilized in a supine position and locally anesthetized with 2% procaine...

2024-07-16

[Animal Modeling Drug Efficacy Evaluation] - Small Pig Alcoholic Fatty Liver Model

Animal models of alcoholic fatty liver are divided into two categories: acute alcoholic fatty liver models and chronic alcoholic fatty liver models...

2024-07-16

[Animal Modeling - Efficacy Evaluation] - Sodium Selenate Cataract Animal Model

　　After reaching the eye tissue lens through fluid circulation, selenite oxidizes the thiol groups of proteins, leading to the inhibition of Ca2+- ATPase. This causes a large accumulation of Ca2+- ATPase in the lens nucleus fibers, leading to the act...

2024-07-16

Animal Modeling Drug Efficacy Evaluation Induced Nasopharyngeal Carcinoma Animal Model

The induced nasopharyngeal carcinoma model is mainly a nasopharyngeal carcinoma animal model formed by the action of chemical carcinogens on animals...

2024-07-16

【Animal Modeling - Pharmacological Evaluation】 - Acute Myeloid Leukemia Animal Model

The human acute myeloid leukemia cell line HL-60 was allogeneic and transplanted into SCID mice with T and B lymphocyte function combined with immune deficiency to establish a SCID mouse model with human hematopoietic function. This is currently the ...

2024-07-16

【Animal Modeling】-Research on Animal Model of Renal Vascular Hypertension

Renal vascular hypertension is the stenosis or obstruction of the main trunk or branches of the renal arteries on one or both sides, which reduces the flow of renal blood vessels and leads to hypertension caused by renal ischemia. It is the most comm...

2024-07-15

【Animal Modeling】-Cloning and Molecular Characterization of the Full-length Coding Sequence of Tree Shrews HGF

To obtain the full-length coding sequence of tree shrew hepatocyte growth factor and analyze its molecular characteristics...

2024-07-12