
Improve the method of extracting rat cerebrospinal fluid based on the negative pressure suction device method, and increase the success rate of rat cerebrospinal fluid collection?...
2024-07-10
To investigate the effect of vitamin D (VD) deficiency on the pathogenesis of spontaneous diabetic rats...
2024-07-10![[Animal modeling] - Establishment and comparison of in situ model of pancreatic cancer in mice suitable for minimally invasive ablation therapy](/./uploads/images/default/default.png)
To explore the advantages and disadvantages of establishing an in situ model of pancreatic cancer in mice by tumor cell injection and tumor tissue transplantation, and to provide a technical reference for establishing an in situ model of pancreatic c...
2024-07-10![[Animal modeling] - Effect of silencing heme oxygenase-1 on the mouse model of acute monocytic leukemia](/./uploads/images/default/default.png)
To investigate the effect of silencing the expression of heme oxygenase-1 (HO-1) on leukemic disease in mice with acute monocytic leukemia...
2024-07-10
A study found that combining a temperature-sensitive dye on a thin, flexible electrical substrate with a distributed light sensor could lead to systems that have the ability to automatically adapt to match the color of their surroundings, as a way fr...
2024-07-10![[Animal Modeling Pharmacodynamic Evaluation]- Mouse Chlamydia Pneumonia Model](/./uploads/images/default/default.png)
The CWL-029 strain of Chlamydia pneumoniae was propagated in HEp-2 cell culture medium. Infected cells were collected using sterile glass beads, destroyed by ultrasound, and purified by centrifugation at low and high speeds for one cycle. They were s...
2024-07-09![[Animal Modeling Pharmacodynamic Evaluation ]- Rat Pneumocystis Pneumocystis Pneumonia Model](/./uploads/images/default/default.png)
Model animals are fed with pellet feed in cages. After observing for one week without any abnormalities, subcutaneous injection of cortisone acetate, 25mg/time, twice a week. At the same time, add tetracycline (100mg/100ml) to drinking water to pre...
2024-07-09![[Animal Modeling - Pharmacodynamic Evaluation] - Small Pig Root Absorption Model](/./uploads/images/default/default.png)
Root resorption is a common and difficult to treat complication in orthodontic treatment, and there are many related factors that can cause root resorption, including age, gender, nutritional status, type of orthodontic device, orthodontic force, ort...
2024-07-08![[Animal Modeling - Pharmacodynamic Evaluation] - Repair of Bone Defects Around Small Pig Implants](/./uploads/images/default/default.png)
Implant restoration has been increasingly widely used in clinical practice, but the loss of teeth due to trauma, tumors, periodontal disease and other reasons often leads to excessive absorption of alveolar bone, resulting in insufficient bone mass a...
2024-07-08![[Animal modeling - Pharmacodynamic evaluation] - Small pig pulpitis model](/./uploads/images/default/default.png)
Five Chinese experimental miniature pigs weighing 14-26kg were used, with three males and two females. Select the first permanent molars of the upper and lower jaw, and create a pulpitis model with bilateral mandibular lateral incisors. After injecti...
2024-07-08
CFW, CBA, BALB/c, DBA, and Kunming mice are all sensitive animals. Inoculate 50ml/3ml of bacteria per foot pad, and after 6-8 months, it can proliferate to 1000000. Generally, 5-8 months after inoculation is a logarithmic growth period, and then ente...
2024-07-08![[Animal Modeling Pharmacodynamic] Evaluation Kidney Deficiency Syndrome Animal Model](/./uploads/images/default/default.png)
The kidney is the foundation of congenital diseases. Kidney deficiency syndrome is one of the main types of syndromes in traditional Chinese medicine, mainly including kidney yang deficiency, kidney yin deficiency, kidney qi deficiency, and kidney es...
2024-07-08![[Animal modeling - efficacy evaluation] - induced diabetes retinopathy animal model](/./uploads/images/default/default.png)
In diabetes, the retina is exposed to high concentration of plasma glucose, and intracellular free glucose accumulates, activating aldose reductase, the key enzyme of sorbitol metabolism. The production of sorbitol is accelerated, and sorbitol accumu...
2024-07-08![[Animal Modeling - Pharmacodynamic Evaluation] - Caries Animal Model](/./uploads/images/default/default.png)
Caries is a progressive damage to dental hard tissue caused by a combination of factors such as bacteria, food, host, and time. If left untreated, the disease can continue to develop, leading to the formation of caries cavities and secondary pulpitis...
2024-07-08![[Animal Modeling Pharmacodynamic] Evaluation Choroidal Melanoma Animal Model](/./uploads/images/default/default.png)
The incidence rate of choroidal melanoma in China is second only to retinoblastoma in children, and it is the most common intraocular malignant tumor in adults...
2024-07-08![[Animal Modeling - Pharmacodynamic Evaluation] - Inducing Lymphoma Animal Model](/./uploads/images/default/default.png)
Chemically induced lymphoma animal model...
2024-07-08