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[Animal model]-HV infection model in suckling mice

[Animal model]-HV infection model in suckling mice

Replication method 48 to 72 hours after delivery, inoculate Kunming sucking mice with 0.02 ml of Hantavirus 76/118 strain (LD5010 -6.5 power/0.02 ml) adapted to sucking mice...

2020-08-11
How to prepare a rodent model of Parkinson\'s disease?

How to prepare a rodent model of Parkinson\'s disease?

Reserpine is an alkaloid that irreversibly prevents monoamine transportation in the capsule and consumes central and peripheral monoamines, thereby affecting the circulation of monoamines in intracellular vesicles. It was used to create a rat PD mode...

2020-08-11
How are rodent models of Alzheimer\'s disease prepared?

How are rodent models of Alzheimer\'s disease prepared?

The aging model of AD animals mainly occurs in the elderly, and aging is a specific risk factor for AD. With the aging of the world population, the prevalence of AD has increased significantly, and it is the fourth leading cause of death in adults, l...

2020-08-11
How to prepare a highly pathogenic avian influenza (H5N1) virus infection model?

How to prepare a highly pathogenic avian influenza (H5N1) virus infection model?

Avian influenza (AI) is an acute, high-contact and severe infection of poultry caused by influenza A virus (avian influenza virus, AIV), which can lead to poultry infection or disease syndrome...

2020-08-11
How to prepare animal models of cerebrovascular disease?

How to prepare animal models of cerebrovascular disease?

Hypertensive animals will develop spontaneous cerebral infarction, which can be divided into two categories: primary hypertension and secondary hypertension. The former is commonly used Japanese spontaneously hypertensive rats (SHR) and its prone sub...

2020-08-11
How to prepare a small animal infection model?

How to prepare a small animal infection model?

Reproduction method Use 10 5.7 power TCID50/ml SARS-CoVBJ201 strain to infect guinea pigs, albino hamsters, black-lined hamsters, rats, brand voles and chickens via nasal drops and infectious doses: guinea pigs 0.5 ml, albino hamsters 0.2 ml , 0.2 ml...

2020-08-11
How to prepare an animal model of TCM exercise-induced fatigue?

How to prepare an animal model of TCM exercise-induced fatigue?

Use fatigue factors, rhubarb and Glauber\'s salt to relieve the effects of drugs and establish an animal model of spleen deficiency...

2020-08-11
How to prepare an animal model of linear impact accelerated head injury?

How to prepare an animal model of linear impact accelerated head injury?

The model was established by Marmarou in 1994. The specific steps for creating the model are: put a prone rat on a foam pad and cut the skin longitudinally to expose the skull...

2020-08-11
How to prepare an animal model of chronic exercise fatigue?

How to prepare an animal model of chronic exercise fatigue?

Replication method Use SD male rats weighing 200-220g, and use a high-intensity treadmill for 7 weeks from the first week of training. The weekly speed is increased to 15m/min, 22m/min, 27m/min, 31m/min. , 35m/min. We will train 5 days a week, 20 min...

2020-08-11
How to prepare an animal model of hypersplenism?

How to prepare an animal model of hypersplenism?

Obesity is a clinical syndrome and one of the most common symptoms in patients with liver cirrhosis. The main clinical symptom is splenomegaly, in which one or more types of blood cells are depleted and bone marrow hematopoietic cells proliferate. Th...

2020-08-10
How to prepare an animal model of diffuse intravascular coagulation?

How to prepare an animal model of diffuse intravascular coagulation?

Disseminated intravascular coagulation (diffuse intravascular coagulation syndrome, DIC) is a clinically acquired syndrome that may be caused by many reasons...

2020-08-10
How to prepare an animal model of hyperlipidemia?

How to prepare an animal model of hyperlipidemia?

Reproduction method In addition to normal feeding conditions, use male KM mice weighing about 35g, using a fat emulsion (fat emulsion) at a dose of 10ml/kg body weight. Management Preparation: Put 80g of lard into a 500ml beaker and dissolve it in an...

2020-08-10
How to prepare animal model of platelet disease?

How to prepare animal model of platelet disease?

Most patients with idiopathic thrombocytopenic purpura (idiopathic thrombocytopenic purpura, ITP) do not have a clear exogenous pathogen, and are detected by antiplatelet antibodies in the blood, and are also related to idiopathic self Immune platele...

2020-08-10
How to prepare animal models of leukocyte disease?

How to prepare animal models of leukocyte disease?

Attenuation studies used to study the toxicity of chemotherapy drugs usually require the establishment of animal models of chemotherapy-induced leukopenia and myelopenia...

2020-08-10
How to prepare an animal model of aplastic anemia?

How to prepare an animal model of aplastic anemia?

Clinically, aplastic anemia (AA) is a group of hematopoietic tissue failure syndromes. Most patients are middle-aged and the prognosis of acute cases is poor...

2020-08-10
How to prepare an animal model of hemolytic anemia?

How to prepare an animal model of hemolytic anemia?

Hemolytic anemia is a group of anemias that occurs when the destruction of red blood cells increases and the speed exceeds the compensatory capacity of hematopoietic function. When the average life span of red blood cells is 15 to 20 days, and the de...

2020-08-10