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How to prepare an animal model of collagen-induced arthritis?

How to prepare an animal model of collagen-induced arthritis?

Since the establishment of the first animal model of collagen-induced arthritis in the 1970s, studies have confirmed the presence of anti-collagen antibodies in the serum and synovial fluid of patients with rheumatoid arthritis, and this autoimmune r...

2020-08-10
How to prepare an animal model of osteoporosis?

How to prepare an animal model of osteoporosis?

Replication method Anesthetize female experimental rats by intraperitoneal injection of 2% sodium pentobarbital at a dose of 40 mg/kg body weight, make a sterile lower abdominal incision, and make abdominal muscles...

2020-08-10
How to prepare animal model of temporomandibular joint osteoarthrosis induced by lactate dehydrogenase?

How to prepare animal model of temporomandibular joint osteoarthrosis induced by lactate dehydrogenase?

Breeding method Adult New Zealand rabbits with edentulous jaws weigh 2.0 to 2.5 kg. After anesthesia, 1 mg/kg body weight of pentobarbital sodium 2.5 g/L is anesthetized from the ear vein, and the maxillary joint is under bacterial conditions....

2020-08-10
How to prepare an animal model of periodontal ligament distraction osteogenesis and rapid tooth movement?

How to prepare an animal model of periodontal ligament distraction osteogenesis and rapid tooth movement?

Copy method Randomly select beagle dogs weighing 12 to 15 kg and 10 to 24 months old. One mandible is the experimental side and the other is the control side....

2020-08-10
How to prepare an animal model of vertebral artery compression?

How to prepare an animal model of vertebral artery compression?

Vertebral artery type cervical spondylosis is caused by degenerative changes of the cervical spine involving the vertebral artery, causing ischemia of the cerebellum and brainstem. As the population ages, the incidence is gradually increasing...

2020-08-08
How to prepare an animal model of avascular necrosis of the femoral head?

How to prepare an animal model of avascular necrosis of the femoral head?

Reproduction method Anesthetized experimental dogs with pentobarbital sodium at a dose of 30 mg/kg body weight. After an incision was made on the animal’s hindlimb and proximal femur, the round ligament was separated and exposed by a lateral incision...

2020-08-08
How to prepare an animal model for traumatic articular cartilage damage repair?

How to prepare an animal model for traumatic articular cartilage damage repair?

Replication method 4 to 5 months old New Zealand rabbits were anesthetized with intraperitoneal ketamine weighing 50 mg/kg and fixed on the surgical plate...

2020-08-08
How to prepare the Kashin-Beck disease animal model?

How to prepare the Kashin-Beck disease animal model?

Cassin-Beck disease (KBD) is an endemic osteoarthritis, the main change is the deep necrosis of the joint epi osteochondral...

2020-08-08
How to prepare an animal model of osteoporosis?

How to prepare an animal model of osteoporosis?

Replication method Anesthetize female experimental rats by intraperitoneal injection of 2% sodium pentobarbital at a dose of 40 mg/kg body weight, make a sterile lower abdominal incision, and make abdominal muscles...

2020-08-08
How to prepare an animal model of distraction osteogenesis to increase the alveolar ridge?

How to prepare an animal model of distraction osteogenesis to increase the alveolar ridge?

Breeding method Choose a beagle with a weight of 10-15 kg and no tooth loss, occlusion disorder or temporomandibular disease...

2020-08-08
How to prepare rat dental fluorosis animal model?

How to prepare rat dental fluorosis animal model?

Breeding method Select female rats weighing 70-100 g after weaning, and prepare a poisoned sodium fluoride solution with double distilled water to make the weight 0.5 ml/100 g...

2020-08-08
【Animal model】-Rhesus monkey periapical disease model

【Animal model】-Rhesus monkey periapical disease model

The method of replication is by intraperitoneal injection of 25-50 mg/kg body weight of adult male rhesus monkeys and anesthetized with 2.5% thiopental sodium solution...

2020-08-08
How to prepare an animal model of pulpitis?

How to prepare an animal model of pulpitis?

Replication method Dilute E. coli standard endotoxin lipopolysaccharide (lipopolysaccharide, LPS) to 5 mg/ml with physiological saline, filter and sterilize for later use...

2020-08-08
How to prepare a tooth-induced pain animal model?

How to prepare a tooth-induced pain animal model?

Breeding method Use a healthy, intact cat, and anesthetize by intraperitoneal injection of sodium pentobarbital at 45 mg/kg body weight...

2020-08-08
How to prepare an animal model of gingival hyperplasia?

How to prepare an animal model of gingival hyperplasia?

Breeding method Ingested clean grade ICR male mice weighing 18-22 g for 6 to 8 weeks, and administered cyclosporin A (CsA) at a dose of 30 mg/kg body weight for 4 consecutive weeks...

2020-08-08
How to prepare oral ulcer animal model?

How to prepare oral ulcer animal model?

Breeding method SD rats weigh 150-180g and take a 6 cm long glass tube at the bottom of 3 mm diameter. The bottom of the swab is flush with the bottom of the glass tube because it contains a small swab...

2020-08-08