![[Dòngwù móxíng]-kǒng yuán xìng shìwǎngmó tuōlí dòngwù móxíng 19/5000 【Animal model】-animal model of rhegmatogenous retinal detachment](/./uploads/images/default/default.png)
Reproduction method: No abnormality in eye examination. Fixed New Zealand rabbits weighing 2.0-2.5 kg, flushed with 1% atropine eye drops to dilate the pupils, and 30 mg per mg was injected into the tail vein of the ear to anesthetize the kilogram of...
2020-08-08![[Animal model]-Optic nerve stretch injury model](/./uploads/images/default/default.png)
Reproduction method Inject pentobarbital sodium with a body weight of 30 mg/kg body weight into a guinea pig weighing about 700 g, incise the outer edge under an operating microscope, cut the corneal limbus into 360°, cut the conjunctiva and eyeball...
2020-08-08
Reproduction method Male and female guinea pigs weigh 300-400 grams, weigh 60-kg/kg body weight, once a day, inject lincomycin hydrochloride or 300 mg/kg body weight lithocholic acid intraperitoneally for 7 consecutive days (every day for 15 consecut...
2020-08-07
Replication method Adult male mice or rats 12 hours after fasting, intraperitoneal injection of D-galactosamine (D-Gal) and endotoxin lipopolysaccharide (LPS) 0.1 at a dose of 800-1000 mg/kg body weight mg/kg Body weight: or adult rats, 30 mg/kg body...
2020-08-07![[Animal Experiment]-Phytolithic cholecystitis model](/./uploads/images/default/default.png)
Reproduction method Inject 3% sodium pentobarbital intravenously to male or female rabbits weighing 2-3kg at a dose of 30mg/kg body weight and use sterile drape anesthesia under the xiphoid...
2020-08-07
Reproduction method Disinfect male or female rabbits weighing 2-3 kg, spread them with a sterile towel, make 3-4 abdominal incisions under the xiphoid process, expose and separate the common bile duct, and remove the common bile duct...
2020-08-07
Reproduction method Male and female rats are forced to take orally 10% 40% CCl4 oil solution/kg body weight, or adult dogs are injected intraperitoneally with 50% CCl4 oil solution 0.9 ml/kg body weight, the hair color of the animals after administra...
2020-08-07
Replication method After fasting for 12 hours, adult rats were injected intraperitoneally with D-galactosamine (D-Gal) at a dose of 1.2-1.8 g/kg body weight...
2020-08-07
In 1908, Ignatowski and colleagues realized that a high-cholesterol diet may be related to the formation of experimental atherosclerosis...
2020-08-07
The adult animal is fixed under anesthesia, the abdomen is opened along the midline of the abdomen, and the inferior vena cava above the renal vein is sutured with purse-string suture with 5-0 vascular suture...
2020-08-07
Model method: Adult rats were anesthetized by intraperitoneal injection of ether or ketamine at 100 mg/kg body weight, fixed on the back, and cut the abdomen along a transabdominal incision...
2020-08-07![[Animal Model]-Model of liver cirrhosis induced by common bile duct ligation](/./uploads/images/default/default.png)
Reproductive method Anesthetize adult rats by performing a midline incision in the abdominal area of the umbilicus, and suture the common bile duct with 7-0 silk suture at 1 cm from the hepatic hilum. It will be stored for 2-8 weeks after the operati...
2020-08-07
Replication method Adult male rats are injected intraperitoneally with 0.5% dimethylnitrosamine (DMNA) at a dose of 10 mg/kg body weight once a day for 4 weeks 3 days a week...
2020-08-07![[Animal model]-Total parenteral nutrition induces fatty liver model (TPN)](/./uploads/images/default/default.png)
Reproduction method Anesthetize adult rats with ether, insert a 0.9mm silicone tube into the internal jugular vein, fix the catheter subcutaneously at the back of the neck, and connect it to a computer infusion pump...
2020-08-07
Replication method PEPCK-nSREBP-1a mice are artificially cultured transgenic mice that develop transient fatty livers after birth, and can regenerate fatty livers through low-sugar and high-protein diets after weaning...
2020-08-07
Breeding method: Feed adult male Wistar rats according to conventional standards, change the drinking water to 10% ethanol beverage, and give 50% ethanol 10 ml/kg body weight twice a day (at 12 hours interval) twice a day for 14 consecutive weeks...
2020-08-07