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How to prepare an animal model for cardiopulmonary bypass?

How to prepare an animal model for cardiopulmonary bypass?

Replication method Rats were intraperitoneally injected with sodium pentobarbital at a dose of 30 mg/kg body weight, intubated through the mouth and mechanically ventilated (frequency 60 times)...

2020-08-06
How to prepare an animal model of coronary artery spasm caused by ovariectomy?

How to prepare an animal model of coronary artery spasm caused by ovariectomy?

Reproduction method The female rhesus monkey is surgically removed from the female ovary, the coronary artery (hereinafter referred to as the coronary artery) is contracted using a vasoconstrictor, and the difference with humans is compared by corona...

2020-08-06
How to prepare animal model of right atrial hypertrophy caused by thoracotomy?

How to prepare animal model of right atrial hypertrophy caused by thoracotomy?

Feeding method Under anesthesia, a dog weighing 20-30 kg is injected intravenously with 30 mg/kg sodium pentobarbital, fixed in the right supine position, and intubated through positive pressure ventilation...

2020-08-06
[Animal model]-Rat model of vasculitis obliterans induced by immune method

[Animal model]-Rat model of vasculitis obliterans induced by immune method

Thromboangiitis obliterans is a peripheral vascular disease dominated by autoimmunity, smoking, cold and other external factors and sex hormones are the main cause of the disease. The following describes the method of using the above-mentioned pathog...

2020-08-06
How to prepare an animal model of lauric acid-induced vasculitis obliterans in rats?

How to prepare an animal model of lauric acid-induced vasculitis obliterans in rats?

Reproduction method Anesthetize male Wistar rats weighing 280-320g by intraperitoneal injection of 35 mg/kg body weight of 3% pentobarbital sodium...

2020-08-06
【Animal model】-Portal hypertension model caused by ligation of the common bile duct

【Animal model】-Portal hypertension model caused by ligation of the common bile duct

Reproduction method Anesthetize male Wistar rats weighing 200-250 g by intraperitoneal injection of 30 mg/kg pentobarbital sodium. Cut the abdominal midline on each layer of the abdominal wall and separate the common bile duct...

2020-08-06
【Animal model】-Thioacetamide-induced portal hypertension model in rats

【Animal model】-Thioacetamide-induced portal hypertension model in rats

Replication method Male Wistar rats weighing 150-200 g are injected intraperitoneally with 50 mg/kg of 3% thioacetamide (TAA) once a day for 16 weeks...

2020-08-06
[Animal model]-Rat model of portal hypertension with carbon tetrachloride liver cirrhosis

[Animal model]-Rat model of portal hypertension with carbon tetrachloride liver cirrhosis

Replication method 230-250 g male SD rats were intraperitoneally injected with CCl4 at a dose of 0.15 ml/kg body weight twice a week, and 0.4 g/L phenobarbital solution was used as drinking water for 4 weeks. , Causing a model of chronic liver injury...

2020-08-06
【Animal model】-Canine model of portal hypertension with carbon tetrachloride liver cirrhosis

【Animal model】-Canine model of portal hypertension with carbon tetrachloride liver cirrhosis

Breeding method: Adult experimental dogs are gavaged with CCl4 at a dose of 2 ml/kg body weight twice a week and once a week, and then gavage with 3% sodium pentobarbital after 12 weeks...

2020-08-06
【Animal Model】-Genetic Engineering Atherosclerosis Model

【Animal Model】-Genetic Engineering Atherosclerosis Model

Replication method 6-8 weeks old ApoE gene-deficient mice (C57BL/6J strain), male 18-20g, female half, ω (fat) = 21%, ω (cholesterol) = 0.15%. \"Western diet\" feed (60CO sterilization radiation treatment), feeding condition is level 2, roo...

2020-08-06
【Animal Model】-Destructive hypothalamic arcuate nucleus atherosclerosis model

【Animal Model】-Destructive hypothalamic arcuate nucleus atherosclerosis model

Replication method Neonatal Wistar rats are injected with 10% sodium glutamate (sodium glutamate, MSG) at a dose of 4 g/kg body weight on the 1, 3, 5, 7 and 9 days after birth...

2020-08-06
How to prepare an animal model of rabbit atherosclerotic plaque caused by carotid artery balloon dilatation?

How to prepare an animal model of rabbit atherosclerotic plaque caused by carotid artery balloon dilatation?

Breeding method An experimental male rabbit weighing about 1.5 kg was anesthetized by intravenous injection of 25% urethane at 1 g/kg body weight, and the right common carotid artery (CCA), right internal carotid artery (ICA) and right outside of the...

2020-08-06
【Animal model】-High methionine atherosclerosis model

【Animal model】-High methionine atherosclerosis model

The male of the replication method experimental rabbit weighs 2.0 to 2.5 kg. After 15 days of adaptive feeding, feed with high methionine feed (standard rabbit feed plus 1% methionine) for 8 weeks...

2020-08-06
How to prepare a rat model of atherosclerosis induced by vitamin D?

How to prepare a rat model of atherosclerosis induced by vitamin D?

Breeding method: Male Wistar rats weighing 180-200g were injected intraperitoneally with 600,000 U/kg of vitamin D and fed with a basic diet...

2020-08-06
How to prepare animal model of macaque cerebral atherosclerosis?

How to prepare animal model of macaque cerebral atherosclerosis?

Replication method In experimental monkeys aged 10 to 16 years, 50-75 mg/kg of epinephrine was intravenously injected once a week. After the epinephrine was stopped, a high-fat diet with 1% cholesterol added 6 times for every 150 g...

2020-08-06
How to prepare quail atherosclerosis animal model?

How to prepare quail atherosclerosis animal model?

Breeding methods Male quails weigh 90-110g and are 5-6 weeks old. Feed containing 1% cholesterol, 1% lard and 1% soybean oil...

2020-08-06