【Animal modeling】-Preparation of rat thoracic aortic vascular smooth muscle cells by an improved two-step compound enzyme digestion method

This paper reports an improved method for the isolation of rat thoracic aortic vascular smooth muscle cells based on compound enzymatic digestion...

2024-06-18

【Animal Modeling】-Effect of REST/NRSF on depression and anxiety-like behavior in corticosterone stress model mice

To study the expression of REST in corticosterone model mice and the effect of REST expression on depression and anxiety behavior in mice, and to explore its role in the mouse model of depression...

2024-06-18

【Animal Modeling】-Safflower Yellow Pigment Protects the Kidneys of Mice with Diabetic Nephropathy and Its Mechanism

To investigate the renal protective effect and mechanism of safflower yellow on streptozotocin-induced diabetic nephropathy in mice...

2024-06-18

【Animal Modeling】-Construction and identification of an immunohumanized mouse model of prostate cancer

To construct a mouse model of humanized immune system and transplant it into human prostate cancer cell lines, so as to be used for the research of prostate cancer immunotherapy drugs...

2024-06-18

【Animal modeling】-Protective effect of GDF11 on myocardial injury in type II diabetic mice

To observe the protective effect of GDF11 on myocardial injury in C57BL/6J mice with type Ⅱ diabetes mellitus and the changes of myocardial apoptosis...

2024-06-18

【Animal Modeling】-Relationship between vascular calcification and bone metabolism markers in rats with chronic kidney disease

To study the correlation between vascular calcification and serum bone metabolism markers in chronic kidney disease rats...

2024-06-17

【Animal Modeling】-Effect of SEL1L gene deletion in central neurons on mouse behavior

To explore the role of endoplasmic reticulum protein SEL1L in maintaining normal physiological activities of mammalian central nervous system...

2024-06-17

【Animal modeling】-Effect of rhubarb root extract on the morphology of tissues and organs in mice with experimental psoriasis

To investigate the effect of rhubarb root extract on the morphology of tissues and organs in experimental psoriasis model mice...

2024-06-17

【Animal Modeling】-Discussion on Influencing Factors of Non-Human Primate Evaluation of Learning and Memory Function

The delayed response test based on the Wisconsin Universal Tester is a common method to evaluate the learning and memory ability of non-human primates. The experiment is affected by many factors during the process. The learning and memory ability has...

2024-06-17

【Animal Modeling】-Preliminary Study on the Toxicity of Different Extracts of Psoralen to Rats

To study the toxicity of oral administration of different extracts of Psoralen to rats, and provide a safety basis for its clinical application...

2024-06-17

【Animal modeling】-Evaluation of the curative effect of Shenling Baizhu powder on ulcerative colitis model mice

To explore the curative effect of Shenling Baizhu Powder on dextran sulfate sodium (DSS)-induced ulcerative colitis model mice...

2024-06-17

【Animal Modeling】-Minocycline inhibits the hyperpolarization-activated current of glial neurons in the dorsal horn of rat spinal cord

To study the effect of minocycline on the hyperpolarization-activated current (Ih) of colloidal (SG) neurons in the spinal dorsal horn of rats...

2024-06-17

【Animal modeling】-Research on the intervention effect and mechanism of down-regulation of AQP-4 on cerebral ischemia-reperfusion injury model rats

To explore the intervention effect and mechanism of down-regulation of AQP-4 on cerebral ischemia-reperfusion injury model rats...

2024-06-17

【Animal Modeling】-The effect of exercise on pancreatic islets in diabetic rats and its mechanism

To investigate the effect of aerobic exercise on pancreatic islets and β cells in type 2 diabetic rats and its mechanism...

2024-06-17

【Animal Modeling】-Analysis of the Rationality of Rabbit KOA Staging Model by Braking Method

To establish different stages of knee osteoarthritis model with plaster immobilization, in order to provide an appropriate animal model for precise treatment of acupuncture and traditional Chinese medicine...

2024-06-17

【Animal modeling】-Protective effect of amygdalin on necrotizing enterocolitis in neonatal rats

To analyze the protective effect of amygdalin on necrotizing enterocolitis (NEC) in neonatal rats...

2024-06-17