【 Animal modeling 】 - Regulatory effect of budesonide on IL-22 in an asthma mouse model

To observe the role of interleukin-22 (IL-22) in asthma models and study the regulatory effects of budesonide on airway inflammation and IL-22 in asthma mouse models...

2024-03-06

Establishment of an animal model of EV71 virus infection in primary renal epithelial cells of tree shrews

To establish an EV71 infection model on primary kidney cells of tree shrews...

2024-03-06

Construction of an animal model of chronic simple lichen in the external genitalia of SD rats and expression of protease activated receptor 2

To establish an animal model of chronic simple lichen in the external genitalia of SD rats, study the expression of protease activated receptor 2 in the model rat external genitalia skin lesions, and provide an ideal animal model for LSC...

2024-03-06

[Animal modeling]- establishment of a mouse model of skin adverse reactions induced by erlotinib

Erlotinib (trade name: Trocaine) is a new targeted drug for the treatment of non-small cell lung cancer. In recent years, it has been widely used in clinical practice, but there are many side effects, with rash being the most common and difficult for...

2024-03-06

[Animal Modeling] - Research Progress of Human Tumor Xenotransplantation Models in Precision Oncology Medicine

Cancer is a series of heterogeneous diseases caused by mutations in oncogenes and tumor suppressor genes caused by physical, chemical, viral and other carcinogenic factors...

2024-03-06

[Animal Modeling] - Study on Optimization Scheme of Ureaplasma Urealyticum Infection Animal Model

To explore the advantages and disadvantages of different modeling methods and select the most suitable animal model method for Mycoplasma urealyticum infection...

2024-03-06

[Animal Modeling] - Evaluation of a Gene Knocked in Mouse Model of Hyperthyroidism, Hypokalemia, and Periodic Paralysis

To establish a hyperthyroidism hypokalemic periodic paralysis model in CaV1.1-R528H mice by knocking in genes and evaluate it...

2024-03-06

[Animal Modeling]- Preparation of a Rat Model of Middle Cerebral Artery Embolism by Carotid Artery Puncture

To compare the timeliness, success rate, and mortality rate of rat middle cerebral artery occlusion (MCAO) models prepared by common carotid artery puncture and traditional thread embolization methods...

2024-03-06

[Animal modeling] - New method and evaluation of constructing rabbit carotid atherosclerotic plaque model

To explore a new method to establish a rabbit model of carotid atherosclerosis by puncture through the central ear artery, using balloon injured common carotid artery intima and high-fat diet...

2024-03-05

【Animal modeling】-The effect of vitamin D deficiency on the pathogenesis of spontaneous diabetic rats

To explore the effect of vitamin D (VD) deficiency on the etiology of spontaneous diabetic rats...

2024-03-05

[Animal modeling] - Prophylactic administration of all trans retinoic acid can alleviate inflammation in rheumatoid arthritis model rats

To explore the effects of all trans retinoic acid on the joint tissue structure, serum expression levels of inflammatory cytokines, and expression levels of cartilage injury related proteins during the formation phase of type II collagen induced rheu...

2024-03-04

[Animal modeling] - establishment of a rat model of renal edema induced by doxorubicin

To investigate the feasibility of replicating a combined model of renal edema in rats...

2024-03-04

[Animal modeling] - Changes in synapses in the inner layer of the retina after chronic elevated intraocular pressure in glaucoma animal models

The synapses of retinal ganglion cell dendrites (RGCs) at the axonal terminals of bipolar cells in the inner reticulum layer (IPL). The changes in dendrites and synapses of bipolar cells in the inner retina may severely impair the function of retinal...

2024-03-04

[Animal Modeling] - Evaluation of a Gene Knocked in Mouse Model of Hyperthyroidism, Hypokalemia, and Periodic Paralysis

To establish a hyperthyroidism hypokalemic periodic paralysis model in CaV1.1-R528H mice by knocking in genes and evaluate it...

2024-03-04

[Animal Modeling] - Preparation of a Rat Model of Middle Cerebral Artery Embolism by Carotid Artery Puncture

To compare the timeliness, success rate, and mortality rate of rat middle cerebral artery embolism models prepared by common carotid artery puncture and traditional thread embolization methods...

2024-03-04

[Animal modeling] - Establishment and pathological observation of a rat model of chronic heart failure caused by aortic arch stenosis

To observe the pathological changes in heart failure caused by aortic arch stenosis in rats...

2024-03-04