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【Animal Modeling】-Animal Model of Digestive System Disease

【Animal Modeling】-Animal Model of Digestive System Disease

The general method is to inject the serum of hepatitis B patients to replicate the hepatitis B model. Most laboratory animals are not affected by the hepatitis A virus. There are reports of human hepatitis A in red-faced macaques, rhesus monkeys, hum...

2023-09-08
【Animal modeling】-The relationship between serum TF, TM, vWF levels and CRT formation in SD rats

【Animal modeling】-The relationship between serum TF, TM, vWF levels and CRT formation in SD rats

To establish a rat model of external jugular vein catheter-related thrombosis (CRT), to observe the formation of CRT in rats, and to detect serum tissue factor (TF), thrombomodulin (TM) and von Willebrand disease in rats. Factor (vWF) content, to stu...

2023-09-08
【Animal modeling】-Comparative study on the pharmacokinetics of Eucommia ulmoides extract in normal rats and SHR models after multiple administrations

【Animal modeling】-Comparative study on the pharmacokinetics of Eucommia ulmoides extract in normal rats and SHR models after multiple administrations

To study the effect of 7 active components of pinoresinol diglucoside, geniposide chlorogenic acid, protocatechuic acid, neochlorogenic acid, cryptochlorogenic acid and pinoresinol monoglucoside after repeated administration of Eucommia ulmoides extr...

2023-09-08
【Animal modeling】-The effect and mechanism of rapamycin on myocardial injury after renal ischemia-reperfusion in rats

【Animal modeling】-The effect and mechanism of rapamycin on myocardial injury after renal ischemia-reperfusion in rats

To investigate the effect of rapamycin on the heart injury of distant organs after renal ischemia-reperfusion in rats...

2023-09-07
[Animal modeling] Urine metabolomics of type 2 diabetes rats with qi yin deficiency syndrome

[Animal modeling] Urine metabolomics of type 2 diabetes rats with qi yin deficiency syndrome

To explore the intrinsic biomaterial basis of Chinese medicine syndromes of type 2 diabetes in adult SD rats from the aspects of metabolic differential markers and metabolic pathways through urine non targeted metabonomics...

2023-09-07
[Animal Modeling] - Formation of Depression Symptoms Induced by Postmenopausal Lipid Metabolic Disorders in Mice

[Animal Modeling] - Formation of Depression Symptoms Induced by Postmenopausal Lipid Metabolic Disorders in Mice

To investigate whether lipid metabolism disorders in postmenopausal women are involved in the formation of depressive symptoms...

2023-09-07
【Animal modeling】-Effect of astragaloside IV on inflammatory factors and ultrastructure in cerebral ischemia-reperfusion rats

【Animal modeling】-Effect of astragaloside IV on inflammatory factors and ultrastructure in cerebral ischemia-reperfusion rats

To observe the effect of astragaloside IV on inflammatory factors and ultrastructure in cerebral ischemia-reperfusion rats...

2023-09-06
【Animal modeling】-Experimental study on loperamide hydrochloride-induced slow transit constipation model in mice

【Animal modeling】-Experimental study on loperamide hydrochloride-induced slow transit constipation model in mice

To compare the differences between the models induced by loperamide hydrochloride in slow transit constipation induced by loperamide hydrochloride and different doses and time, and to explore the establishment of a stable loperamide hydrochloride-ind...

2023-09-06
【Animal modeling】-MRI and ultrastructural analysis of hippocampus of APP/PS1 double transgenic AD model mice

【Animal modeling】-MRI and ultrastructural analysis of hippocampus of APP/PS1 double transgenic AD model mice

To observe the relationship between the changes of metabolites in the hippocampus of APP/PS1 transgenic mice and ultra-pathological changes, so that the gene mice can be better used in the experimental study of Alzheimer\\\'s disease (AD)...

2023-09-06
【Animal Modeling】-Acupuncture improves symptoms of insomnia rats and effects on spontaneous activity by regulating GABA-Gln metabolism

【Animal Modeling】-Acupuncture improves symptoms of insomnia rats and effects on spontaneous activity by regulating GABA-Gln metabolism

To study the improvement of symptoms of acupuncture on insomnia rats and its effect on spontaneous activity, and to explore its possible mechanism...

2023-09-06
【Animal Modeling】-Analysis of fecal microbial diversity of wild tree shrews using Illumina MiSeq sequencing platform

【Animal Modeling】-Analysis of fecal microbial diversity of wild tree shrews using Illumina MiSeq sequencing platform

To analyze the structure and composition of the fecal flora of wild tree shrew by high-throughput sequencing technology, and to lay a foundation for the further development and utilization of this new experimental animal...

2023-09-06
【Animal modeling】-Effect of curcumin pretreatment on myocardial oxidative stress and apoptosis in rats with heat stroke in dry heat environment

【Animal modeling】-Effect of curcumin pretreatment on myocardial oxidative stress and apoptosis in rats with heat stroke in dry heat environment

To observe the effect of curcumin pretreatment on myocardial oxidative stress and apoptosis in rats with heat stroke in a dry heat environment and to explore its possible mechanism...

2023-09-06
【Animal modeling】Effect of -17βestradiol on propofol-induced apoptosis of cortical neurons

【Animal modeling】Effect of -17βestradiol on propofol-induced apoptosis of cortical neurons

To investigate the effect and mechanism of 17β-estradiol on the apoptosis of primary cultured cortical neurons induced by propofol...

2023-09-06
【Animal Experiment】-Lion facial recognition technology launched in Africa

【Animal Experiment】-Lion facial recognition technology launched in Africa

Now, even the king of the jungle can hardly avoid the camera to take close-up shots of their faces. Recently, Kenyan lion guardians launched a Lion Identification Cooperation Network (LINC). The lion face database also established the world’s first u...

2023-09-06
【Animal modeling】-Stable expression of human coagulation factor IX gene in mouse adipose stem cells

【Animal modeling】-Stable expression of human coagulation factor IX gene in mouse adipose stem cells

To transfect C57BL/6 mouse adipose-derived mesenchymal stem cells with recombinant adenovirus carrying human coagulation factor IX (hFIX) gene (F9). Vector cells for hemophilia gene therapy...

2023-09-06
【Animal Modeling】-Preliminary Study on the Changes of Tongue Gene Expression Profile in Rats with Qi Stagnation and Blood Stasis Syndrome

【Animal Modeling】-Preliminary Study on the Changes of Tongue Gene Expression Profile in Rats with Qi Stagnation and Blood Stasis Syndrome

To study the changes of the whole gene expression profile in the tongue of rats with qi stagnation and blood stasis syndrome and the biological processes and pathways involved in differential genes by using gene chip technology, in order to provide s...

2023-09-06