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【Animal modeling】-Preparation and evaluation of MPTP-induced C57BL/6 mouse Parkinson\\

【Animal modeling】-Preparation and evaluation of MPTP-induced C57BL/6 mouse Parkinson\\

To establish a stable 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)-induced Parkinson\\\'s model in C57BL/6 mice, and to evaluate the model\\\'s behavior...

2023-07-24
【Animal Modeling】-Carbon tetrachloride induced inbred C57BL/6 mice to establish liver fibrosis model

【Animal Modeling】-Carbon tetrachloride induced inbred C57BL/6 mice to establish liver fibrosis model

To compare the effects of different doses of carbon tetrachloride in inducing hepatic fibrosis in inbred C57BL/6 mice, so as to establish a stable hepatic fibrosis model...

2023-07-24
【Animal model】-Portal hypertension model caused by ligation of the common bile duct

【Animal model】-Portal hypertension model caused by ligation of the common bile duct

Propagation method Pentobarbital sodium (30 mg/kg body weight) was injected intraperitoneally into male Wistar rats weighing 200 to 250 g, and the midline of the abdomen was cut in each layer of the abdominal wall to separate the common bile duct. Cu...

2023-07-24
【Animal modeling】-Preparation and preliminary identification of rabbit anti-marmoset IgG-HRP-labeled antibody

【Animal modeling】-Preparation and preliminary identification of rabbit anti-marmoset IgG-HRP-labeled antibody

To purify IgG antibody from marmoset serum, prepare rabbit anti-marmoset antiserum, and purify IgG from antiserum, HRP (horseradish peroxidase)-labeled rabbit anti-marmoset IgG...

2023-07-24
[Animal model]-Speed dating of birds can reduce reproductive capacity

[Animal model]-Speed dating of birds can reduce reproductive capacity

Most studies on how animals choose companions focus on the quality indicators of the evaluation, assuming that all individuals agree to find attractive companions, and hardly pay attention to the reasons why personal preferences will change...

2023-07-24
【Animal Modeling】-Making a Rabbit Myocardial Infarction Model with Minimally Invasive Cardiac Catheterization

【Animal Modeling】-Making a Rabbit Myocardial Infarction Model with Minimally Invasive Cardiac Catheterization

To investigate the myocardial infarction (MI) model in rabbits created by occlusion of coronary artery by cardiac catheterization...

2023-07-21
【Animal modeling】-Establishment and applicability evaluation of animal model of pelvic organ prolapse

【Animal modeling】-Establishment and applicability evaluation of animal model of pelvic organ prolapse

To establish a rat animal model that can reflect the similar pathological changes of the sacral ligament in patients with pelvic organ prolapse, to explore the effects of increasing the intensity of birth trauma and simulating menopause on the histop...

2023-07-21
[Animal modeling] - Explore the molecular mechanism of resveratrol against myocardial ischemia-reperfusion injury in rats based on network pharmacology

[Animal modeling] - Explore the molecular mechanism of resveratrol against myocardial ischemia-reperfusion injury in rats based on network pharmacology

To explore the effect of resveratrol on myocardial ischemia reperfusion injury in rats and its mechanism in vivo based on the screening method of network pharmacological information...

2023-07-21
[Animal modeling] - Spirillum hepatica infection promotes the development of nonalcoholic fatty liver disease in mice induced by high-fat diet

[Animal modeling] - Spirillum hepatica infection promotes the development of nonalcoholic fatty liver disease in mice induced by high-fat diet

To investigate the effect of Spirillum hepaticum infection on nonalcoholic fatty liver disease induced by high-fat diet...

2023-07-20
【Animal modeling】-Application of three mouse enterovirus nucleic acid detection technologies in mouse health monitoring

【Animal modeling】-Application of three mouse enterovirus nucleic acid detection technologies in mouse health monitoring

To use nucleic acid detection technology to detect MHV, Reo-3 and MNV enteroviruses in mouse cecal contents, and to compare the results with serological detection results to analyze the applicability of nucleic acid detection in mouse health monitori...

2023-07-20
【Animal Modeling】-Study on the establishment of a rat model of coronary heart disease combined with Qi deficiency and blood stasis syndrome

【Animal Modeling】-Study on the establishment of a rat model of coronary heart disease combined with Qi deficiency and blood stasis syndrome

To explore the establishment of the rat model of CHD combined with qi deficiency and blood stasis syndrome by analyzing the tongue manifestations of the rat model of coronary heart disease with qi deficiency and blood stasis syndrome combined with pa...

2023-07-20
【Animal modeling】-Effect of sugar supplementation on the activation of adenosine monophosphate-activated protein kinase in the myocardium of acute exercise rats

【Animal modeling】-Effect of sugar supplementation on the activation of adenosine monophosphate-activated protein kinase in the myocardium of acute exercise rats

To investigate the effect of sugar supplementation on the activation of AMPK in exercise myocardium by measuring the changes in myocardial adenosine monophosphate-activated protein kinase activity and glycogen content after acute exercise in rats...

2023-07-18
【Animal modeling】-Mechanism of jujube saponins alleviating Alzheimer\\

【Animal modeling】-Mechanism of jujube saponins alleviating Alzheimer\\

To investigate the mechanism of jujube saponin (ZSS) alleviating sevoflurane anesthesia in 9-month-old APP/PS1/tau triple transgenic Alzheimer\\\'s disease model mice...

2023-07-18
【Animal Modeling】-Analysis of Thyroid Function in Chronic Intermittent Hypoxia Model Rats

【Animal Modeling】-Analysis of Thyroid Function in Chronic Intermittent Hypoxia Model Rats

To explore the relationship between obstructive sleep apnea hypopnea syndrome and thyroid function in a rat model of chronic intermittent hypoxia...

2023-07-18
【Animal Modeling】-Effect of Atractylodes Rhizoma Extract on gastric mucosa and gastrointestinal immune function in rats with spleen deficiency syndrome

【Animal Modeling】-Effect of Atractylodes Rhizoma Extract on gastric mucosa and gastrointestinal immune function in rats with spleen deficiency syndrome

To investigate the protective effect of Atractylodes Rhizoma extract on gastric mucosa and its effect on gastrointestinal immune function in spleen deficiency model rats, and to clarify the mechanism of ERA\\\\\\\'s intervention in spleen deficiency ...

2023-07-17
【Animal Modeling】- Establishment of a mouse model of lung metastasis and postoperative recurrence after bone marrow injection

【Animal Modeling】- Establishment of a mouse model of lung metastasis and postoperative recurrence after bone marrow injection

To establish a model of lung metastasis and postoperative recurrence by bone marrow injection, to reveal the superiority and feasibility of the model by bone marrow injection, and to provide a new research basis for the study of lung metastasis of ma...

2023-07-17