【Animal modeling】-Design and efficacy evaluation of anti-reflux device for positioning evaluation of orotracheal intubation in experimental rats

To improve the positioning technique of orotracheal intubation in experimental rats, improve the efficiency of endotracheal intubation and reduce complications...

2022-11-17

[Animal Modeling]-Sterile APPswe/PS1ΔE9 double transgenic mouse model

A sterile APPswe /PS1ΔE9 (PAP) double transgenic mouse model was established by cesarean section, and preliminary observation of plaque deposition in the animal\\\\\\\'s brain provided new ideas for studying the relationship between intestinal flora ...

2022-11-17

【Animal modeling】-Correlation between gut microbes and anti-dsDNA antibody levels in mice with systemic lupus erythematosus

To investigate the relationship between the gut microbiota structure and anti-dsDNA antibodies in TC mice with systemic lupus erythematosus (lupus for short)...

2022-11-17

【Animal modeling】-FGF-2/PELA/BMP-2 microcapsule scaffold promotes the osteogenic differentiation of rat periosteum-derived stem cells

To observe the effect of fibroblast growth factor-2/polylactic acid-polyethylene glycol-polylactic acid/bone morphogenetic protein-2 (FGF-2/PELA/BMP-2) microcapsule scaffold on the formation of periosteum-derived stem cells in SD rats. Bone different...

2022-11-17

【Animal Modeling】-Preliminary study on the interference of Helicobacter hepaticus infection on the immune response of BALB/c mice

To investigate the interference of Helicobacter hepatica infection on the surface molecular morphology and immune response of mouse bone marrow-derived dendritic cells (DC)...

2022-11-16

【Animal Modeling】-Mechanism of platelets in salt-sensitive hypertension through inflammatory response

To investigate the role and molecular mechanism of platelets in high-salt-induced salt-sensitive hypertension...

2022-11-16

【Animal modeling】-The regulatory effect of Wuji pills on brain-gut peptides in rats with post-inflammatory irritable bowel syndrome

To find biological indicators for the diagnosis and treatment of irritable bowel syndrome (IBS)....

2022-11-16

【Animal Modeling】-Aniline-induced DNA damage in mouse hepatocytes and lymphocytes and its repair effect

To study the genotoxicity of aniline and its repair kinetics...

2022-11-16

[Animal modeling] Preventive and therapeutic effects of diaminazine in rats with pulmonary hypertension

To investigate the preventive and therapeutic effects of diaminazine (DIZE) on pulmonary hypertension (PAH) in rats...

2022-11-16

【Animal modeling】-Effect of Lycium barbarum polysaccharide on tumor growth and metastasis in spontaneous breast cancer MMTV-PyMT mice

To investigate the effect of Lycium barbarum polysaccharide on the growth and metastasis of breast cancer using MMTV-PyMT mice as a breast cancer model...

2022-11-15

【Animal Modeling】-The damage characteristics of olfactory working memory in the very early stage of Alzheimer\\

To investigate the characteristics of olfactory working memory impairment in the very early stage of Alzheimer\\\'s disease transgenic mice...

2022-11-15

【Animal Modeling】-Effect of intrauterine injection of absolute ethanol on estrous cycle in mice

To investigate the effect of intrauterine injection of absolute ethanol on the estrous cycle of mice...

2022-11-15

【Animal Modeling】-How to establish a mouse model of alcoholic cardiomyopathy?

Establish a mouse alcoholic cardiomyopathy model through a liquid diet to provide an excellent animal model for studying the pathogenesis of alcoholic cardiomyopathy...

2022-11-14

【Animal Modeling】-Effect of hydrogen sulfide on myocardial fibrosis and expression of MAPK1/3 and MMP-8 in diabetic rats

To investigate the effect of gas signal molecule hydrogen sulfide (H2S) on myocardial fibrosis and protein expression of MAPK1/3 and MMP-8 in diabetic rats...

2022-11-14

【Animal modeling】-The neuroprotective effect of artesunate on experimental autoimmune encephalomyelitis mice and the effect of autophagy

To investigate the neuroprotective effect and autophagy of artesunate on experimental autoimmune encephalomyelitis (EAE) mice...

2022-11-14

【Animal Modeling】-Interventional effect of flavonoids in Sandianjin on ulcerative colitis mice and their effects on intestinal flora

To investigate the intervention effect of the national medicine Sandianjin total flavonoids and its monomer compounds vervasoflavone and formononetin on dextran sodium sulfate (DSS)-induced ulcerative colitis (UC) mice. Influence of gut microbiota...

2022-11-14