【Animal Modeling】-Scientists try to use young blood to regenerate aging tissues in animal experiments

Xenosymbiosis is a 150-year-old surgical technique that connects the vasculature of two living animals. It mimics natural instances of shared blood supply, such as conjoined twins or animals sharing the same placenta in the womb...

2022-09-30

【Animal Modeling】-Types of β-amyloid and the Pathogenesis Model of Alzheimer\\

Inoculation of mice with brain homogenates from sporadic Alzheimer\\\'s disease patients elicited cerebral amyloid deposition in recipients, suggesting that the amyloid beta (Aβ) peptide may self-proliferate as a prion...

2022-09-30

【Animal modeling】-Effect of rosuvastatin on myocardial matrix metalloproteins and inflammatory factors in rats with acute myocardial infarction

To observe the changes of matrix metalloproteinase MMPs, TIMP2 and inflammatory factors TNF-α and IL-1β in myocardial tissue of rats with acute myocardial infarction (AMI) treated with rosuvastatin...

2022-09-30

【Animal Modeling】-Expression of NF-κB in Hepatocytes of Rats with Welfare Injury Induced by Braking

To study the expression changes of NF-κB in hepatocytes of rats with welfare injury induced by immobilization...

2022-09-30

【Animal Modeling】-Determination of blood concentration of carbamazepine in rats after administration and its NMR metabolomics analysis

To analyze the effect of carbamazepine on the serum metabolome of rats after intragastric administration using nuclear magnetic resonance (NMR)-based metabolomics technology...

2022-09-30

【Animal modeling】-Protective effect of atorvastatin on joint injury in ApoE-/- mice

To observe the protective effect of atorvastatin on joint injury in ApoE-/- mice...

2022-09-30

[Animal modeling] - Protective effect of curcumin on acute renal injury in rats with pregnancy induced hypertension

To investigate the protective effect of curcumin on acute renal injury induced by pregnancy induced hypertension in rats and explore its potential mechanism...

2022-09-29

[Animal modeling] - Experimental study on lung tissue damage in rats caused by dental grinding dust

To evaluate the effects of cobalt chromium molybdenum metal (trade name: Vitaline), zirconia porcelain and polymethyl methacrylate resin on lung injury in rats...

2022-09-29

[Animal modeling] - Effect of prostacyclin E1 on hepatic fibrosis in rabbits after hepatic artery iodized oil embolization

To investigate the effect of prostacyclin E1 on the expression of Smad2 and Smad4 mRNA in rabbits with hepatic fibrosis after hepatic artery iodized oil embolization...

2022-09-29

[Animal modeling] Protective effect of atorvastatin on joint injury in ApoE -/- mice

To observe the protective effect of atorvastatin on joint injury in ApoE -/- mice...

2022-09-29

【Animal Modeling】-Application of L-Arginine in the Propagation of Drosophila in the Laboratory

The purpose of the experiment was to study the effect of adding L-arginine to corn agar medium on the pupation time, eclosion time, eclosion rate and male-female ratio of Drosophila melanogaster...

2022-09-29

【Animal Modeling】-Study on the differential expression of lysozyme 1 in the incubation and resting blastocysts before and after superovulation in mice

To study the distribution and expression of the hemolysin LYZ1 gene in the hatched blastocysts and dormant embryos of mice before and after high ovulation, and explore the new regulatory mechanism during the process of animal embryo implantation?...

2022-09-29

【Animal modeling】-Application of experimental material detection in quality control of SPF experimental mice

To explore the feasibility and application value of testing experimental materials in SPF laboratory mouse barrier facilities...

2022-09-29

【Animal modeling】-Observation of multimodal molecular functional imaging of female rhesus monkey kidneys at different ages

To observe various imaging indexes such as GFR, ADC, SUV, CT value of female rhesus monkey kidney in different age groups, and to explore the effect of age on various imaging quantitative indexes of female rhesus monkey kidney...

2022-09-29

【Animal Modeling】-Comparison of two different reagents for the four detection results of hemagglutination in SD rats

To compare the four-item (PT, APTT, TT, FIB) detection results of hemagglutination reagents (PT, APTT, TT, FIB) in experimental animals SD rats and humans with two different brands of hemagglutination reagents imported and domestic to observe whether...

2022-09-29

[Animal modeling] - Effect of Oct4 and Cdx2 on differentiation of bovine embryo inner cell mass and trophoblast

To study the effect of Oct4 and Cdx2 knockdown on the gene expression related to the differentiation of bovine ICM and TE, and to explain the role of Oct4 and Cdx2 in the early development of bovine embryos...

2022-09-28