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[animal modeling] - effect of salidroside on Nrf2 / Keap1 signaling pathway and wound healing in diabetes foot ulcer rats

[animal modeling] - effect of salidroside on Nrf2 / Keap1 signaling pathway and wound healing in diabetes foot ulcer rats

To investigate the effect of salidroside (Sal) on nuclear transcription factor E2-related factor 2 / Kelch-like epichlorohydrin-related protein 1 (Nrf2 / Keap1) signaling pathway and wound healing in diabetic foot ulcer (DFU) rats...

2022-09-28
【Animal Modeling】-Regulatory effects of corstine on skin inflammation and autophagy in psoriasis mice by inhibiting C5a/C5aR1 pathway

【Animal Modeling】-Regulatory effects of corstine on skin inflammation and autophagy in psoriasis mice by inhibiting C5a/C5aR1 pathway

To investigate the regulatory effect of Cosentyx on skin inflammation and autophagy in psoriatic mice through the C5a/C5aR1 pathway through the imiquimod (IMQ) mouse model of psoriasis...

2022-09-28
【Animal Modeling】-Effect of Qingre Runzao Oral Liquid on the upstream and downstream cytokines of ILC2s in asthmatic mice

【Animal Modeling】-Effect of Qingre Runzao Oral Liquid on the upstream and downstream cytokines of ILC2s in asthmatic mice

To intervene ovalbumin (OVA)-sensitized asthmatic mice with Qingre Runzao Oral Liquid, and to observe its effect on the number of type II innate lymphocytes (ILC2s) and its upstream and downstream cytokines in asthmatic mice...

2022-09-28
【Animal modeling】-Intervention effect and mechanism of Exendin-4 on STZ-induced diabetic nephropathy in rats

【Animal modeling】-Intervention effect and mechanism of Exendin-4 on STZ-induced diabetic nephropathy in rats

To study the intervention effect and possible mechanism of Exendin-4 on streptozotocin-induced diabetic nephropathy in rats...

2022-09-28
【Animal Modeling】-Research on the analgesic effects of Lugai Qishan Fluoxane on labor and delivery based on MAPK signaling hypoxia

【Animal Modeling】-Research on the analgesic effects of Lugai Qishan Fluoxane on labor and delivery based on MAPK signaling hypoxia

To investigate the effect of sevoflurane labor analgesia on hypoxia in neonatal rats based on the mitogen-activated protein kinase (MAPK) signaling pathway...

2022-09-28
【Animal modeling】-Intervention effect of chitosan on PM2.5-induced acute lung injury in mice

【Animal modeling】-Intervention effect of chitosan on PM2.5-induced acute lung injury in mice

To investigate the intervention effect of chitosan on PM2.5-induced acute lung injury in mice...

2022-09-27
【Animal modeling】-Effect of microcystin-LR on mitochondrial function of mouse primary hepatocytes

【Animal modeling】-Effect of microcystin-LR on mitochondrial function of mouse primary hepatocytes

Microcystin pollution caused by cyanobacterial blooms is one of the world\'s concerns...

2022-09-27
【Animal Modeling】-The effect of carbon tetrachloride-induced acute liver injury on the heart in a rat model

【Animal Modeling】-The effect of carbon tetrachloride-induced acute liver injury on the heart in a rat model

To investigate the effect of carbon tetrachloride on cardiac function and morphology in rats with acute liver injury...

2022-09-27
【Animal Modeling】-NOD2 promotes the production of nitrosamine by diethyl nitrosamine to study the mechanism of inducing liver tissue inflammation in mice

【Animal Modeling】-NOD2 promotes the production of nitrosamine by diethyl nitrosamine to study the mechanism of inducing liver tissue inflammation in mice

To investigate the role and mechanism of NOD2, a pattern recognition receptor in hepatocytes, in the process of hepatic inflammation...

2022-09-27
【Animal Modeling】-Antibiotic-induced microbiome depletion promotes intestinal colonization of Campylobacter jejuni in mice

【Animal Modeling】-Antibiotic-induced microbiome depletion promotes intestinal colonization of Campylobacter jejuni in mice

To establish a method for intestinal colonization of C57BL/6 mice by Campylobacter jejuni through antibiotic-induced gut microbiome depletion...

2022-09-27
【Animal Modeling】-Effect of Tongxinluo on the early lesions of calcific aortic valve disease in mice

【Animal Modeling】-Effect of Tongxinluo on the early lesions of calcific aortic valve disease in mice

To observe whether Tongxinluo intervention can delay the progression of calcific aortic valve disease in the early stage...

2022-09-27
【Animal modeling】-Effect of microcystin-LR on mitochondrial function of mouse primary hepatocytes

【Animal modeling】-Effect of microcystin-LR on mitochondrial function of mouse primary hepatocytes

Microcystin contamination caused by cyanobacterial blooms is one of the topics of concern worldwide. Microcystin LR (MC-LR) has strong specific hepatotoxicity, but the exact mechanism of its hepatic injury has not been fully elucidated...

2022-09-26
【Animal Modeling】-Effect of REST/NRSF on depression and anxiety-like behavior in corticosterone stress model mice

【Animal Modeling】-Effect of REST/NRSF on depression and anxiety-like behavior in corticosterone stress model mice

To study the expression of REST in corticosterone model mice and the effect of REST expression on depression and anxiety behavior in mice, and to explore its role in the mouse model of depression...

2022-09-26
【Animal Modeling】-Manufacture and Application of Laser Localizer for Experimental Animal Magnetic Resonance Imaging System

【Animal Modeling】-Manufacture and Application of Laser Localizer for Experimental Animal Magnetic Resonance Imaging System

To design and develop a simple laser locator for rats and mice, and to provide a safe, convenient, accurate, low-cost and easy-to-operate experimental tool for medical nuclear magnetic resonance experiments...

2022-09-26
【Animal modeling】-Effect of IGF-1 gene and electrical stimulation therapy on rat model of postpartum stress urinary incontinence

【Animal modeling】-Effect of IGF-1 gene and electrical stimulation therapy on rat model of postpartum stress urinary incontinence

To study the effect of IGF-1 gene therapy on the rat model of postpartum stress urinary incontinence, and to explore the ideal treatment method for the disease...

2022-09-24
【Animal modeling】-Effect of sesame oil on the expression of insulin sensitivity-related genes in skeletal muscle of insulin-resistant rats

【Animal modeling】-Effect of sesame oil on the expression of insulin sensitivity-related genes in skeletal muscle of insulin-resistant rats

To investigate the effect of a high-fat diet of thulia oil rich in n-3 polyunsaturated fatty acids on insulin sensitivity and the expression of related genes in insulin-resistant rats...

2022-09-24