【Animal modeling】-Lithium chloride combined with calcium phosphate bone cement can promote the repair of tibial bone defect in rats

To observe the effect of calcium phosphate cement (CPC) and lithium chloride combined calcium phosphate cement (Li/CPC) on fracture healing in SD rats...

2022-07-21

【Animal modeling】-Comparison of repeated administration toxicity between doxorubicin liposome injection and doxorubicin injection in rats

To study the toxic effects of doxorubicin liposome injection and doxorubicin injection by continuous intravenous injection on rats and compare the similarities and differences of toxicity...

2022-07-21

【Animal modeling】-Effect of bee venom on TrkA and TRPV1 in dorsal root ganglia of rats with collagen-induced arthritis inflammatory pain

To investigate the effect of bee venom on TrkA and TRPV1 pain signaling molecules in collagen-induced arthritis rats...

2022-07-21

【Animal Modeling】-Effects of chronic corticosterone treatment on learning and memory and synapse-related proteins in mice

To establish a drinking method, chronically administer corticosterone, and observe the effects of corticosterone on learning and memory and synapse-related proteins...

2022-07-21

【Animal modeling】-The phenotypic characteristics of lymphocytes in HBV transgenic mice and the effect of interferon α on them

To investigate the phenotypic characteristics of lymphocytes in hepatitis B virus (HBV) transgenic mice and the effect of interferon α on virological indexes and immune cell phenotypes...

2022-07-21

【Animal Modeling】-Effects of chronic arsenic exposure on brain and serum metabolomics in mice

To observe the effects of chronic arsenic exposure on the metabolomics of mouse cortex and serum, and to explore its neurotoxicity mechanism...

2022-07-20

【Animal Modeling】-The relationship between sex differences in blood pressure and sodium channels in mouse kidneys

To study blood pressure, renal urinary sodium excretion and related renal sodium channels and signaling pathways in male and female mice, and to preliminarily explore the relationship between sex differences in blood pressure and renal sodium channel...

2022-07-20

【Animal Modeling】-Study on vascular calcification and expression of vascular wall osteopontin and osteocalcin in aged rats

To study the occurrence of vascular calcification in aged rats, and the changes of osteopontin and osteocalcin expression in the arterial vessel wall of aged rats...

2022-07-20

【Animal Modeling】-A weekly subcutaneous injection of rhPTH(1-34) promotes fracture healing in rats

To observe the effect of weekly subcutaneous injection of parathyroid hormone rhPTH (1-34) on fracture healing in rats...

2022-07-20

【Animal Modeling】-Comparison of the difference of glutamate-induced swelling of cultured astrocytes between two varieties of rats

To compare the differences of glutamate-induced cell swelling by cultured astrocytes (AST) in Wistar rats and SD rats...

2022-07-20

【Animal Modeling】-Drug efficacy and pain mechanism in mice with adenomyosis

To understand the efficacy and pain mechanism of drug therapy in mice with adenomyosis...

2022-07-20

【Animal Modeling】-Discussion on the pathological evaluation method of polio vaccine intracerebral monkey neurovirulence test

To investigate the pathological evaluation method of polio vaccine in monkey neurovirulence test by intracerebral method...

2022-07-20

【Animal modeling】-Comparative study of bone metabolism in WHBE rabbits with forelimb deformity based on OPG/RANK/RANKL system

To use the OPG/RANK/RANKL system to compare and study the bone metabolism characteristics of WHBE rabbits with forelimb deformity...

2022-07-20

【Animal modeling】-The effect of glutamine combined with umbilical cord blood mesenchymal stem cell transplantation on intestinal ischemia-reperfusion injury in rats

To investigate the effect of glutamine combined with cord blood mesenchymal stem cells (MSCs) transplantation on intestinal ischemia-reperfusion injury in rats...

2022-07-20

【Animal modeling】-Effect of low selenium diet on the expressions of CD163, CD206 and CCR7 in the liver and kidney of rats

To investigate the effect of low selenium diet on liver and kidney in rats, and the role of macrophage polarization to M1 and M2 in liver and kidney fibrosis...

2022-07-20

【Animal Modeling】-Glucagon-like polypeptide-1 improves learning and memory ability in type 2 diabetic rats

To observe the improvement effect of diabetes treatment drug glucagon-like peptide-1 (GLP-1) on learning and memory dysfunction in diabetic rats...

2022-07-20