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【Animal modeling】-Discuss the protective effect and mechanism of activated protein C on myocardial ischemia-reperfusion injury in rats

【Animal modeling】-Discuss the protective effect and mechanism of activated protein C on myocardial ischemia-reperfusion injury in rats

To investigate the protective effect and mechanism of activated protein C (APC) on myocardial ischemia-reperfusion injury in rats...

2022-07-08
【Animal Modeling】-Effect of hypoxia training on Ghrelin-GHSR pathway in obese mice

【Animal Modeling】-Effect of hypoxia training on Ghrelin-GHSR pathway in obese mice

To apply hypoxic training to obese mice to observe the changes of GHSR levels in gastric tissue and hypothalamus, so as to explore whether hypoxic training affects the Ghrelin-GHSR pathway to improve obesity...

2022-07-08
【Animal modeling】-Observation of the effect of thrombopoietin on cardiomyocyte apoptosis in rats with heart failure induced by adriamycin based on TGF-β1/Smad3 signaling pathway

【Animal modeling】-Observation of the effect of thrombopoietin on cardiomyocyte apoptosis in rats with heart failure induced by adriamycin based on TGF-β1/Smad3 signaling pathway

To investigate the effect of thrombopoietin (TPO) on cardiomyocyte apoptosis in rats with adriamycin-induced heart failure (CHF) and its regulatory mechanism on TGF-β1/Smad3 signal...

2022-07-08
【Animal modeling】-Study on the protective effect of curcumin on cognitive function and neurological function in mice with cerebral ischemia-reperfusion injury

【Animal modeling】-Study on the protective effect of curcumin on cognitive function and neurological function in mice with cerebral ischemia-reperfusion injury

To investigate the effect of curcumin on cognitive function, neurological function and mechanism of cerebral ischemia-reperfusion injury in mice...

2022-07-08
【Animal modeling】-Effect of hydroxychloroquine on spleen lymphocytes in lupus mice

【Animal modeling】-Effect of hydroxychloroquine on spleen lymphocytes in lupus mice

To observe the effect of hydroxychloroquine on the distribution of lymphocytes in peripheral immune organs (spleen) of mice with systemic lupus erythematosus (TC mice)...

2022-07-08
【Animal Modeling】-Comparison of Depression and Anxiety-like Behaviors in Mice of Different Ages

【Animal Modeling】-Comparison of Depression and Anxiety-like Behaviors in Mice of Different Ages

To observe and compare the depression and anxiety-like behaviors of experimental mice of different ages...

2022-07-08
【Animal modeling】-The effect of simulated aging rat astrocyte conditioned medium on the proliferation of neural stem cells

【Animal modeling】-The effect of simulated aging rat astrocyte conditioned medium on the proliferation of neural stem cells

To establish a rat astrocyte aging model, simulate the aging of astrocytes in aged rats, and explore the effect of aging astrocyte conditioned medium on the proliferation of neural stem cells...

2022-07-08
【Animal Modeling】-Effect and mechanism of acute liver injury in mice on brown adipose tissue function

【Animal Modeling】-Effect and mechanism of acute liver injury in mice on brown adipose tissue function

To investigate the effects of carbon tetrachloride (CC14 ) on brown adipose tissue in mice with acute liver injury at different time points and the related mechanisms...

2022-07-08
【Animal modeling】-The role of up-regulation of p-CaMKⅡ expression in dorsal root ganglion in rats with diabetic neuralgia

【Animal modeling】-The role of up-regulation of p-CaMKⅡ expression in dorsal root ganglion in rats with diabetic neuralgia

To observe the expression of phosphorylated calcineurin II (p-CaMK II) in the dorsal root ganglia of diabetic neuropathic pain model rats at different stages...

2022-07-08
【Animal Modeling】-The role of atrial natriuretic peptide in pulmonary metastasis of melanoma in knockout mice

【Animal Modeling】-The role of atrial natriuretic peptide in pulmonary metastasis of melanoma in knockout mice

To investigate the effect of atrial natriuretic peptide on pulmonary metastasis of melanoma...

2022-07-08
【Animal modeling】-Preparation of curcumin nanoemulsion and its protective effect on myocardial ischemia-reperfusion in rats

【Animal modeling】-Preparation of curcumin nanoemulsion and its protective effect on myocardial ischemia-reperfusion in rats

To construct curcumin (CUR) nanoemulsion drug delivery system and study its protective effect and mechanism on myocardial ischemia-reperfusion in rats...

2022-07-08
【Animal modeling】-Effect of taurine on growth axis hormones and genes in intrauterine growth restriction pregnant mice

【Animal modeling】-Effect of taurine on growth axis hormones and genes in intrauterine growth restriction pregnant mice

To observe the effect of taurine on the expression of blood hormones and IGF gene in intrauterine growth restriction pregnant mice...

2022-07-08
【Animal Modeling】-Effects of Unpredictable Stress Stimulation on the Immunity and Microflora of the Gastrointestinal Tract in Rats

【Animal Modeling】-Effects of Unpredictable Stress Stimulation on the Immunity and Microflora of the Gastrointestinal Tract in Rats

To analyze the effects of unpredictable stress on the gastrointestinal immune system and microbial population by observing the rats after 9 days of unpredictable stress stimulation, so as to provide reference for the study of chronic stress on gastro...

2022-07-07
【Animal Modeling】-Influence of the placement time of venous blood cell suspension on the determination of blood routine in mice

【Animal Modeling】-Influence of the placement time of venous blood cell suspension on the determination of blood routine in mice

To observe the effect of placing time of venous blood cell suspension on blood routine determination in mice...

2022-07-07
【Animal Modeling】-Correlation of BDNF and VEGF expression in hippocampus and forebrain cortex and chronic stress-induced depression in mice

【Animal Modeling】-Correlation of BDNF and VEGF expression in hippocampus and forebrain cortex and chronic stress-induced depression in mice

To investigate the correlation between the expression of brain-derived neurotrophic factor (BDNF) and vascular endothelial growth factor (VEGF) in hippocampus and forebrain cortex and chronic stress-induced depression in mice...

2022-07-07
【Animal Modeling】-Isoproterenol-induced myocardial ischemia-induced changes in the pathological tissue of myocardial cells

【Animal Modeling】-Isoproterenol-induced myocardial ischemia-induced changes in the pathological tissue of myocardial cells

To observe the expression of HE staining, VEGF (vascular endothelial growth factor) and FCF (fibroblast growth factor) in myocardial tissue sections induced by subcutaneous injection of isoproterenol (1 mg/kg body weight) for different days in rats w...

2022-07-07