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【Animal modeling】- Down-regulation of miR-128-3p alleviates inflammatory response and lung histomorphology in acute lung injury in septic rats

【Animal modeling】- Down-regulation of miR-128-3p alleviates inflammatory response and lung histomorphology in acute lung injury in septic rats

To investigate the effect of down-regulation of miR-128-3p on inflammatory response and lung histomorphology in acute lung injury in septic rats...

2022-07-06
【Animal Modeling】-Evaluation of the effect of midazolam and butorphanol on anesthesia in mice before isoflurane anesthesia

【Animal Modeling】-Evaluation of the effect of midazolam and butorphanol on anesthesia in mice before isoflurane anesthesia

To observe the anesthesia effect and internal environment stability of mice receiving midazolam combined with butorphanol before isoflurane anesthesia, and evaluate the safety...

2022-07-06
【Animal modeling】-The expression significance of c-Myc, RhoA and YAP in chronic kidney disease induced by the expression of adenosine

【Animal modeling】-The expression significance of c-Myc, RhoA and YAP in chronic kidney disease induced by the expression of adenosine

To observe the expressions of renal c-Myc, RhoA and YAP proteins in adenine-induced chronic kidney disease model in rats and their relationship with tubulointerstitial fibrosis...

2022-07-06
【Animal modeling】-Exploration of the effect of pomegranate tonic syrup on anemia in Wistar rats

【Animal modeling】-Exploration of the effect of pomegranate tonic syrup on anemia in Wistar rats

To investigate the effect of pomegranate tonic syrup on anemia in Wistar rats...

2022-07-06
【Animal Modeling】-The effect of miR-328 on the expression of L-type calcium channel in thoracic aorta of hypertensive rats by exercise

【Animal Modeling】-The effect of miR-328 on the expression of L-type calcium channel in thoracic aorta of hypertensive rats by exercise

To investigate the promoting effect of microRNA-328 (miR-328) in improving the expression of L-type voltage-gated calcium channel in thoracic aortic smooth muscle cells of hypertensive rats by aerobic exercise...

2022-07-06
【Animal Modeling】-Construction and identification of an immunohumanized mouse model of prostate cancer

【Animal Modeling】-Construction and identification of an immunohumanized mouse model of prostate cancer

To construct a mouse model of humanized immune system and transplant it into human prostate cancer cell lines, so as to be used for the research of prostate cancer immunotherapy drugs...

2022-07-06
【Animal Modeling】-Animal study on two different types of left atrial appendage occluder

【Animal Modeling】-Animal study on two different types of left atrial appendage occluder

To evaluate the feasibility and safety of occlusion of the left atrial appendage in animals with two different left atrial appendage occluders, the single-disc cylindrical type and the double-disc split type...

2022-07-06
【Animal modeling】-The expression significance of c-Myc, RhoA and YAP in chronic kidney disease induced by the expression of adenosine

【Animal modeling】-The expression significance of c-Myc, RhoA and YAP in chronic kidney disease induced by the expression of adenosine

To observe the expressions of renal c-Myc, RhoA and YAP proteins in adenine-induced chronic kidney disease model in rats and their relationship with tubulointerstitial fibrosis...

2022-07-05
【Animal Modeling】-The effect of miR-328 on the expression of L-type calcium channel in thoracic aorta of hypertensive rats by exercise

【Animal Modeling】-The effect of miR-328 on the expression of L-type calcium channel in thoracic aorta of hypertensive rats by exercise

To investigate the promoting effect of microRNA-328 (miR-328) in improving the expression of L-type voltage-gated calcium channel in thoracic aortic smooth muscle cells of hypertensive rats by aerobic exercise...

2022-07-05
【Animal Modeling】-The effect of human umbilical cord mesenchymal stem cells on the level of autophagy in the hippocampus of natural aging rats

【Animal Modeling】-The effect of human umbilical cord mesenchymal stem cells on the level of autophagy in the hippocampus of natural aging rats

To investigate whether transplantation of human umbilical cord mesenchymal stem cells can improve learning and memory and cognitive decline by regulating the level of autophagy in naturally aging rats...

2022-07-05
【Animal modeling】-Study on differential expression of lysozyme 1 in hatched and dormant blastocysts before and after superovulation in mice

【Animal modeling】-Study on differential expression of lysozyme 1 in hatched and dormant blastocysts before and after superovulation in mice

To study the distribution and expression of lysozyme LYZ1 gene in hatched blastocysts and dormant embryos of mice before and after superovulation, and to explore the new regulatory mechanism of animal embryo implantation...

2022-07-04
【Animal modeling】-Optimization of SD rat skin chemical hair removal parameters based on D-optimal design

【Animal modeling】-Optimization of SD rat skin chemical hair removal parameters based on D-optimal design

To study the depilation parameters of SD rat skin, and to provide basic experimental conditions for establishing skin photoaging animal model...

2022-07-04
【Animal modeling】-Propofol protects against cerebral ischemia-reperfusion injury and may be related to the inhibition of gap junction function

【Animal modeling】-Propofol protects against cerebral ischemia-reperfusion injury and may be related to the inhibition of gap junction function

To investigate the relationship between the protective effect of propofol on cerebral ischemia-reperfusion injury and gap junctions and its possible mechanism...

2022-07-04
【Animal Modeling】-Effect of ovariectomy on skin aging in osteoporotic rats

【Animal Modeling】-Effect of ovariectomy on skin aging in osteoporotic rats

The osteoporosis model constructed by ovariectomized rats is the most suitable model for the study of postmenopausal osteoporosis...

2022-07-04
What is an animal with NK cell immune deficiency? -【Animal Modeling】

What is an animal with NK cell immune deficiency? -【Animal Modeling】

Beige mice are mutant mice with immunodeficiency in NK cells, and bg is a recessive mutant gene on chromosome 13...

2022-07-04
【Animal Modeling】-Effects of Unpredictable Stress Stimulation on the Immunity and Microflora of the Gastrointestinal Tract in Rats

【Animal Modeling】-Effects of Unpredictable Stress Stimulation on the Immunity and Microflora of the Gastrointestinal Tract in Rats

To analyze the effects of unpredictable stress on the gastrointestinal immune system and microbial population by observing the rats after 9 days of unpredictable stress stimulation, so as to provide reference for the study of chronic stress on gastro...

2022-07-04