【Animal Experiment】-The effect of rapamycin on the proliferation of rat aortic valve interstitial cells

Using rapamycin as a target to inhibit mTOR and study its effect on the proliferation of rat heart valve stromal cells...

2020-08-22

[Animal experiment]-Study on subacute inhalation toxicity of Ivermectin to rats

To study the subacute inhalation toxicity of ivermectin to rats to achieve the maximum unobserved effect level...

2020-08-22

[Animal Experiment]-Study the changes of platelet mitochondria after tourniquet limb ischemia-reperfusion injury

Explore the changes of platelet mitochondria after tourniquet ischemia-reperfusion injury, and provide guidance on the clinical application of hemostasis...

2020-08-22

[Animal experiment]-The effect of apoptosis signal regulatory protein 1 on the expression of GFAP, vimentin and hind limb motor function after spinal cord injury in rats

To explore the expression of apoptotic signal regulatory protein 1 (ASK1) in the glial scar after spinal cord injury (SCI), the expression of its protein, glial fibrillary acidic protein (GFAP) and vimentin (vimentin) and its effect on the hind limbs...

2020-08-22

[Animal experiment]-The changes of telemetry EEG activity in the submarginal zone of morphine-dependent rats during the period of drug-seeking subsidence

To explore the effect and mechanism of changing the subconscious cortex (IL) telemetry EEG activity on drug-seeking behavior in the process of drug withdrawal in morphine-dependent rats...

2020-08-22

[Animal experiment]-Expression and immunolocalization of the main egg antigen Sjp40 of Schistosoma japonicum in the liver of New Zealand white rabbits

Observe the expression of Sjp40 in liver eggs of New Zealand white rabbits and the formation of granulomas, and carry out immunolocalization...

2020-08-22

[Animal experiment] -Wnt7a-Akt/mTOR signaling pathway in the improvement of skeletal muscle atrophy in CRF rats

To explore the effect and mechanism of Wnt7a-Akt/mTOR signaling pathway in improving renal failure nutritional capsules for skeletal muscle atrophy in rats with chronic renal failure (CRF)...

2020-08-22

【Animal Experiment】-The effect of chronic intermittent hypoxia on the expression of glucose transporter 4 in rat skeletal muscle

To explore the effects of inflammatory factors caused by chronic intermittent hypoxia and reoxygenation on glucose metabolism and skeletal muscle glucose transporter 4 (GLUT-4) expression in rats...

2020-08-22

[Animal experiment]-Sap2 protein and dendritic cell immune protection against systemic Candida albicans infection

Immunize mice with recombinant protein and dendritic cells (DC) to observe its protective effect on systemic Candida albicans...

2020-08-22

[Animal experiment]-Protective effect of Ulinastatin on acute lung injury in mice with severe heatstroke

Sixty SPF male C57/BL6 mice were randomly divided into 6 groups (n = 10): normal group, severe heatstroke model group, treatment group, normal saline. Simulation group and saline group after each simulated administration...

2020-08-22

[Animal experiment]-Determination of blood drug concentration of carbamazepine in rats after administration and its nuclear magnetic resonance metabolomics analysis

Using nuclear magnetic resonance (NMR)-based metabonomics technology to analyze the effect of carbamazepine on the serum metabolome of rats after intragastric administration...

2020-08-22

Stem cell repair therapy succeeds in animal experiments

Stem cell therapy can regenerate human tissues damaged by trauma, disease or aging. According to the latest news from the University of South Wales (UNSW) in Australia, the university’s research team has made breakthroughs in this field and successfu...

2020-08-22

[Animal Experiment]-Effect of propofol on lung metastasis and expression of MTA1 and Wnt1 in tumor-bearing rats

To study the effects of different doses of propofol on the expression of MTA1 and Wnt1 in rat MADB106 cell lung metastasis and tumor tissue...

2020-08-22

[Animal experiment]-Tanshinone IIA sodium sulfonate reduces the occurrence of postoperative peritoneal adhesions in rats by enhancing the activity of the peritoneal fibrinolytic system

To evaluate the preventive and therapeutic effects of Tanshinone ⅡA sulfonate (STS) on postoperative peritoneal adhesions in experimental rats and explore its mechanism...

2020-08-22

[Animal experiment]-The effect of serum and indoxyl sulfate from patients with chronic renal insufficiency on lipid accumulation of macrophages

To observe the effect of uremic toxin indoxyl sulfate on aortic atherosclerosis in uremic apoE-/- mice, serum of patients with chronic renal failure, macrophage cholesterol transport receptor expression and intracellular lipid accumulation...

2020-08-22

[Animal experiment]-The effect of aluminum phosphate gel and Kangfuxin liquid on the histology, IL-8 and PGE2 of the esophagus in rats with lysolecithin-related reflux esophagitis

To explore the effect of aluminum phosphate gel and phase bean toxin solution on the esophageal structure and IL-8, PGE2 content of lysolecithin-related reflux esophagitis rats and its possible mechanism...

2020-08-22