[Animal Experiment]-Effect of Tripterygium Glycosides on the Expression of Hypoxia Inducible Factor-1α and Endothelin-1 in Kidney Tissue of Diabetic Rats

To study the effect of Tripterygium wilfordii polyglycoside on the expression of hypoxia-inducible factor-1α (HIF-1α) and endothelin-1 (ET-1) in the kidney tissue of diabetic rats, and to study its damage to the kidney, to study Tripterygium wilfordi...

2020-08-22

【Animal Experiment】-Adenovirus-mediated shRNA targeting NF-κB gene affects the proliferation activity of cynomolgus monkey endometrial cells in vitro

Design shRNA adenovirus vector carrying NF-κB-p65 gene and empty gene, culture cynomolgus monkey endometrial cells in vitro, divide them into experimental group and control group, and add NF-κB to the experimental group...

2020-08-22

【Animal Experiment】-The effect of dexamethasone pollution in drinking water on the intestinal flora of mice

Twenty Balb/c mice were randomly divided into a control group and an experimental group, 5 in each group. The drinking water received by the experimental low-dose group contained 0.035g dexamethasone sodium phosphate, the medium-dose group was 0.225g...

2020-08-22

[Animal experiment]-The effect of acute incision pain on the expression of connexin Cx43 in the spinal dorsal horn of rats

Eighty male SD rats were randomly divided into a control group and an acute incision model group. In the incision pain model group, a longitudinal incision was made on the left hind paw of all rats, and the incision pain model was prepared before and...

2020-08-22

[Animal experiment]-LXRα RNA interference mediated by recombinant lentivirus improves the function of rat fatty liver donor liver transplantation

[Animal experiment]-LXRα RNA interference mediated by recombinant lentivirus improves the function of rat fatty liver donor liver transplantation...

2020-08-22

[Animal experiment]-Pathological changes of amyloid cerebrovascular disease in Alzheimer\'s disease rats

Based on the establishment of experimental animal models of Alzheimer’s disease in rats, to explore the pathological characteristics of brain tissue in amyloid cerebrovascular disease...

2020-08-22

[Animal Experiment]-Scientists implanted 3D printed ovaries in mice and successfully conceived

Scientists at Northwestern University used a 3D printer to create artificial ovaries and transplanted them into mice from which the original ovaries had been removed...

2020-08-22

【Animal Experiment】-Edaravone can reduce oxidative stress and delay myocardial fibrosis in rats

Fifty 8-week-old male SD rats were randomly divided into 5 groups (control group, model group, edaravone low, medium and high concentration groups)...

2020-08-22

[Animal experiment]-Oral human interferon-α transformed bifidobacteria promotes the proliferation and maturation of mouse lymphocytes

Construction of Escherichia coli-Bifidobacterium shuttle expression vector pBADX-hIFNα2b containing human IFN-α gene, electrotransformation of IFN-α gene into bifidobacteria, and induction of hIFN by L-arabinose...

2020-08-22

【Animal Experiment】-Effect of stress duration of plantar electric shock on anxiety-like behavior in rats

According to body weight, adult male SD rats were randomly divided into control group and plantar electric shock group, with 12 rats in each group...

2020-08-21

[Animal experiment]-Pathological observation of microsphere embolization agent on renal artery embolism in Beagle dogs

Establish a canine renal artery embolization model with microsphere embolization agent to evaluate the effects of unilateral renal artery embolization and local tissue observation in dogs...

2020-08-21

[Animal experiment]-High-fat, high-purine diet combined with potassium oxazine induced quail glucose and lipid metabolism disorder and its complications

Combine a high-fat diet with a high-hypoxanthine diet + oxazine potassium to establish a model to detect the dynamic changes of quail serum uric acid and triglycerides, and determine the serum-related indicators after the end of the experiment. The a...

2020-08-21

[Animal Experiment]-New Model of American Cancer Research: New tumor samples will be cultured in mice

The National Cancer Institute (NCI) announced that the NCI-60 cell line, which has been used by researchers around the world for 25 years, will be \"retired\" at the end of this spring. It will be replaced by donations from cancer patients ...

2020-08-21

[Animal experiment]-Study on the protective effect of Ginkgo biloba extract on MPTP-induced Parkinson\'s mice

Observe the effect of Ginkgo biloba extract (GBE) on 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) induced by Parkinson\'s disease (PD) at different ages...

2020-08-21

【Animal Experiment】-Mice experiment proved for the first time that running helps fight cancer

Does exercise help fight cancer? Scientists at the University of Copenhagen in Denmark found for the first time through experiments in mice that running helps slow the growth of tumors....

2020-08-21

【Animal Experiment】-The effect of low molecular weight heparin sodium adjuvant on the humoral immune response of mice induced by hepatitis A virus vaccine

To explore the effect of low molecular weight heparin sodium (LMWH-Na) adjuvant on the humoral immune response of hepatitis A virus (HAV) vaccine in mice...

2020-08-21