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How to prepare animal models of viral keratitis?

How to prepare animal models of viral keratitis?

Viral keratitis (viral keratitis) is the most common herpes simplex keratitis (HSK)...

2020-08-03
How to prepare an animal model of acute epilepsy?

How to prepare an animal model of acute epilepsy?

Acute epilepsy models are usually acute epileptic seizure models that can induce epilepsy with one treatment, including maximum electric shock (MES) epilepsy models and pentylenetetrazol (PTZ) epilepsy models...

2020-08-03
How to prepare the AD animal model related to aging?

How to prepare the AD animal model related to aging?

AD mainly affects the elderly and is a disease associated with aging. Aging plays an important role in the pathogenesis of AD. This type of model regards aging as the cause of AD, and uses various methods and means to promote animal aging, including ...

2020-08-03
[Animal model]-Spontaneous SLE mouse model

[Animal model]-Spontaneous SLE mouse model

ZB/BINJ mice suffer from hemolytic anemia, increased immunoglobulin content, and autoimmune abnormalities, such as anti-nuclear antibodies, anti-DNA antibodies, and anti-thymic antibodies. Immune complex glomerulonephritis; ZW/LacJ mice are usually n...

2020-08-03
【Animal model】-Activated lymphocytes and their chromatin induce SLE mouse model

【Animal model】-Activated lymphocytes and their chromatin induce SLE mouse model

The lymphocytes of activated inbred mice can be used as antigens to immunize the same mice so that the host can produce its own anti-dsDNA antibodies, anti-nuclear antibodies, etc....

2020-08-03
How to prepare animal models of spontaneous leukemia?

How to prepare animal models of spontaneous leukemia?

AKR spontaneous leukemia mice are born with carcinogenic RNA viruses, and their response to drug treatment is similar to childhood acute lymphoblastic leukemia (ALL)...

2020-08-03
How to prepare animal model of aplastic anemia?

How to prepare animal model of aplastic anemia?

Aplastic anemia (aplastic anemia) usually refers to the primary myelogenetic syndrome of unknown cause. It mainly manifests as low bone marrow production, pancytopenia, anemia, bleeding and infection...

2020-08-03
How to prepare animal model of hemorrhagic anemia?

How to prepare animal model of hemorrhagic anemia?

Anemia after acute hemorrhage is anemia caused by rapid heavy bleeding, while anemia after chronic hemorrhage is small cell anemia caused by long-term moderate bleeding....

2020-08-03
How to prepare an animal model of hemolytic anemia?

How to prepare an animal model of hemolytic anemia?

Róngxiě xìng pínxiě (HA) shì yī zhǒng chángjiàn de pínxiě lèixíng, tā dǎozhì hóngxìbāo cúnhuó shíjiān jiào duǎn, bìngqiě yóuyú mǒu zhǒng yuányīn ér bèi pòhuài, chāochūle gǔsuǐ de bǔcháng nénglì, tā shì yī zhǒng chángjiàn de zàoxiě jíbìng. 70/5000 H...

2020-08-03
How to prepare animal models of ischemic anemia?

How to prepare animal models of ischemic anemia?

Iron deficiency anemia (Ironemia anemia, IDA) refers to iron deficiency caused by various reasons and anemia caused by a decrease in red blood cells. IDA is the most common anemia, and its incidence is significantly higher in infants and women of chi...

2020-08-03
How to prepare an animal model of transplanted lymphoma?

How to prepare an animal model of transplanted lymphoma?

Using established lymphoma cell lines or patient lymphoma tissues transplanted into immunodeficient animals, transplanted lymphoma models can be established and tumor characteristics can be characterized....

2020-07-31
How to prepare animal models of induced lymphoma?

How to prepare animal models of induced lymphoma?

The most commonly used inducer is N-methylnitrosourea (MNU). Its carcinogenic mechanism is related to the formation of O6-methylguanine, which causes GyA point mutations during DNA replication...

2020-07-31
How to prepare genetically modified leukemia animal models?

How to prepare genetically modified leukemia animal models?

By cloning and analyzing the promoter sequence and function of the mouse Tec gene, the genes controlled by the Tec promoter are only specifically expressed in the cytoplasm of hematopoietic stem cells...

2020-07-31
How to prepare an animal model of hyperuricemia?

How to prepare an animal model of hyperuricemia?

Hyperuricemia is caused by a variety of reasons, including excessive uric acid production and/or reduced renal uric acid excretion, leading to supersaturation of urate levels in the extracellular fluid. For men and postmenopausal women, if the blood ...

2020-07-31
How to prepare animal models of induced pituitary tumors?

How to prepare animal models of induced pituitary tumors?

Long-term stimulation with estrogen can induce PRL tumors in the pituitary gland in rats, but the specific mechanism has not been fully elucidated. For example, after long-term administration of estrogen to F344 rats, the glands may grow abnormally i...

2020-07-31
Preparation scheme of spontaneous diabetes animal model

Preparation scheme of spontaneous diabetes animal model

Spontaneously diabetic animals, also called spontaneously hyperglycemic animals, are naturally occurring diabetic animals or diabetic models preserved through genetic breeding and culture, and their performance is the same as that of human diabetic a...

2020-07-31