【Animal Modeling】-Observation of Pulse Wave Velocity and Arterial Wall Structure in Spontaneously Hypertensive Rats of Different Ages

By measuring the pulse wave velocity (PWV) of spontaneously hypertensive rats (SHR) at different ages, and analyzing the structure of aortic media cross-sectional area (MCSA) of SHR at the same time, reveal the physiological changes of blood vessels...

2024-05-14

【Animal Modeling】-Effect and mechanism of acute liver injury in mice on brown adipose tissue function

To investigate the effects of carbon tetrachloride (CC14 ) on brown adipose tissue in mice with acute liver injury at different time points and the related mechanisms...

2024-05-14

[Animal modeling] - alprostadil on eIF2 of rats with fulminant liver failure α/ Effects of ATF4/CHOP pathway on liver function

To investigate the effect of prostaglandin e 1 (PGE1) on liver function in rats with fulminant liver failure (FHF) and its effect on eukaryotic translation initiation factor 2 α (eIF2 α) / Activates the regulation of the transcription factor 4 (ATF4)...

2024-05-14

【Animal modeling】-improvement and evaluation of rat myocardial ischemia-reperfusion injury model

To improve the preparation method of the rat model of acute myocardial ischemia-reperfusion injury, and make a comprehensive evaluation, so as to lay a good model foundation for the follow-up research on MI/RI...

2024-05-10

【Animal Modeling】-Experimental Study on Rat Model of Hypertension Complicated with Hyperlipidemia

To construct a rat model of hypertension complicated with hyperlipidemia by feeding spontaneously hypertensive rats (SHR) with high-fat diet, and to evaluate the damage of the heart and kidney, so as to provide a useful reference for the treatment of...

2024-05-10

【Animal modeling】-Establishment and mechanism of BALB/c mouse model of total hysterectomy

To establish an experimental animal model of total hysterectomy in BALB/c mice, and to explore and analyze the characteristics and formation mechanism of the model...

2024-05-10

【Animal modeling】-radioprotective effect of diallyl disulfide on mouse spermatogenic cells

To study the radioprotective effect of diallyl disulfide on mouse spermatogenic cells...

2024-05-08

【Animal modeling】-The protective effect and mechanism of glycyrrhizic acid on hippocampal neuron damage in epileptic rats

To investigate the protective effect and related mechanism of glycyrrhizic acid on hippocampal neuron damage in epileptic rats...

2024-05-08

【Animal modeling】-The regulatory effect of Wuji pills on brain-gut peptides in rats with post-inflammatory irritable bowel syndrome

To find biological markers for the diagnosis and treatment of irritable bowel syndrome...

2024-05-08

【Animal Modeling】-Quality Control of Chromosomal Specimen Preparation in Hamster In Vitro Chromosomal Aberration Test

To investigate the influencing factors and quality control of the chromosome preparation process in the in vitro chromosome aberration test, and to summarize and analyze the successful preparation methods and key points of in vitro chromosome specime...

2024-05-08

[Animal modeling] - Establishment of an experimental model of distraction osteogenesis in rats

To establish a new model of tibia distraction osteogenesis in SD rats...

2024-05-08

【Animal modeling】-Effect of oat β-glucan on the expression of genes related to small intestinal injury in sepsis

To explore the effect of oat β-glucan on the expression of genes related to small intestinal injury in sepsis...

2024-05-07

【Animal modeling】-Immunomagnetic bead separation technology combined with flow cytometry to detect ENU-induced Pig-a gene mutation in rats

To enrich and detect mutant red blood cells in peripheral blood of rats by combining immunomagnetic bead separation technology and flow cytometry, and to optimize the pig-a gene mutation test method in peripheral blood of rats...

2024-05-07

【Animal Modeling】-improved New Zealand Rabbit Common Carotid Artery Cannulation Fixation Method

To investigate a stable, not easy to fall off, and continuous and timed blood collection method for the common carotid artery cannulation of New Zealand rabbits...

2024-05-07

【Animal Modeling】-Establishment and mechanism of high-fat and high-salt diet-induced hypertension model in Bama miniature pigs

To establish a hypertensive model of Bama miniature pigs with a high-fat and high-salt diet, and to explore its possible pathogenesis...

2024-05-07

[Animal modeling] - construction of a bioluminescent human liver cancer nude mouse in situ cancer model

To select a stable expression of luciferase reporter gene in human liver cancer cell line (HCCLM3 Luc) and construct a nude mouse model of in situ cancer bearing human liver cancer cell line...

2024-05-06