【Animal modeling】-Protective effect of ulinastatin on acute lung injury in severe heatstroke mice

To discuss the maintenance effect of ulinastatin on acute lung injury in severe heatstroke mice...

2024-05-20

[Animal modeling] - Atherosclerosis model of hypothalamic arcuate nucleus lesion

Newborn Wistar rats were subcutaneously injected with 10% monosodium glutamate in the back at a dose of 4g/kg body weight on the 1st, 3rd, 5th, 7th, and 9th day after birth, for a total of 5 injections...

2024-05-20

[Animal modeling] - Genetic engineering atherosclerosis model

6-8 week old ApoE gene deficient mice (strain C57BL/6J), half male and half female, weighing 18-20g, fed with ω (Fat)=21% ω (Cholesterol)=0.15% of \\\\\\\"Western type diet\\\\\\\" feed (treated with 60CO sterilization and irradiation), fee...

2024-05-20

[Animal modeling] - Portal vena cava anastomosis induced portal hypertension model

Adult experimental hybrid dogs weighing around 15kg were fasted before surgery and anesthetized by intravenous injection of 3% pentobarbital sodium at a dose of 30mg/kg body weight. The inferior vena cava and portal vein were anastomosed laterally wi...

2024-05-20

[Animal Modeling] - Human Gastric Cancer Orthotopic Transplantation and Metastasis Model in Nude Mice

The nude mouse orthotopic transplantation model of human gastric cancer often adopts subcutaneous transplantation method, and the transplanted tumor generally does not metastasize...

2024-05-20

【Animal Modeling】-Correlation between cognitive development and hippocampal dopamine and doxyl acetic acid in 80-day-old offspring born from fear of injury

To investigate the effects of 80-day-old offspring on cognitive development and the content of dopamine and dopamine in hippocampus, and to explore the correlation between the two...

2024-05-20

【Animal Modeling】-The inhibitory effect of miRNA-144 gene overexpression on hepatocellular carcinoma mice and its influence on intestinal flora

To analyze the antitumor effect of microRNA-144 (miRNA-144) gene overexpression on hepatocellular carcinoma mice and its influence on intestinal flora...

2024-05-20

【Animal modeling】-Effect of deoxycholic acid on the growth of ileal organoids in C57BL/6 mice

To establish a mouse intestinal organoid culture system, and to investigate the effect of deoxycholic acid (DCA) on the growth of intestinal organoids...

2024-05-20

【Animal modeling】-Development and preliminary application of a waste gas treatment device for experimental animal facilities

To develop a device suitable for waste gas treatment in laboratory animal facilities, and to verify the effect through field application...

2024-05-20

【Animal modeling】-Comparison of drug-induced syndromes induced by prednisolone in different strains of mice

To study the differences in the degree of suppression of adrenal cortex function and the induction of drug-induced syndromes after glucocorticoids act on different strains of mice...

2024-05-20

【Animal Modeling】-Study on the characteristics of spontaneous hindlimb paralysis in hyperlipidemia susceptible (WSHc) rats

To observe the pathogenesis and pathological characteristics of spontaneous hindlimb paralysis rats in the hyperlipidemia susceptible (WSHc) rat population, and to preliminarily study its pathogenesis and explore its application and scientific resear...

2024-05-20

【Animal Modeling】-Effect of endometriosis on the fertility of mice

To establish a mouse model of endometriosis, and to observe the effect of endometriosis on the pregnancy ability of the model mice...

2024-05-17

[Animal modeling]- canine acute necrotizing pancreatitis model

Pancreatobiliary obstruction, bile reflux, or duodenal reflux can interfere with the normal function of glandular cells, leading to activation of trypsinogen by intracellular lysosomal enzymes, resulting in pancreatitis...

2024-05-17

[Animal Modeling] - Animal Model of Hypertensive Kidney Yin Deficiency Syndrome

Adult rats were subjected to nephrectomy on one side and ligation of 2/3 of the renal artery on the other side. The tail artery blood pressure of the rats was measured 2 weeks after surgery, and those with systolic blood pressure>140mmHg (18.6kPa)...

2024-05-17

[Animal Modeling] - S180 Sarcoma Kidney Yin Deficiency Animal Model

Adult mice were used to prepare S180 tumor cells into 1g/4ml physiological saline cell suspension, and 0.2ml of each was inoculated subcutaneously in the armpit of the right forelimb. Starting from the next day, T4120mg and 0.8mg/(kg body weight · d)...

2024-05-17

【Animal Modeling】 - Amino Hypnotic Method for Kidney Yang Deficiency Animal Model

Adult rabbits were given a gastric tube at regular times every morning at a dose of 6mg/kg body weight to administer Amiodarone (distilled water mixed with 10mg/ml suspension) for 15 consecutive days. Daily detailed observation and recording of chang...

2024-05-17