【 Animal Modeling 】 - Constructing an Experimental Autoimmune Myasthenia Gravis Mouse Model Using the Black Spot Double Fined Torpedo

To establish an experimental autoimmune myasthenia gravis animal model that meets international preclinical experimental standards...

2024-04-07

【Animal modeling】-Experimental study on the preparation of SD rat portal hypertension animal model by ligation of left branch

To explore whether simple left portal vein ligation can form stable portal hypertension and whether nitric oxide plays a corresponding role in it...

2024-04-03

【Animal modeling】-Effect of hypoxia on the expressions of drug transporters MDR1 and MRP2 in rats

To study the effects of simulated rapid altitude hypoxia on some physiological indexes and the expressions of MDR1 and MRP2 efflux drug transporters in the small intestine, liver and kidney of rats, and to preliminarily explore the effect of high alt...

2024-04-03

[Animal modeling] - Comparison of insulin resistance atherosclerosis models between white haired black eye rabbits and Japanese big ear rabbits

To investigate the phenotypic difference and pathological mechanism of insulin resistance atherosclerosis models in white haired black eyed (WHBE) rabbits and Japanese white eared (JW) rabbits...

2024-04-02

【Animal Modeling】-Using the seasonal influenza virus H3N2 mouse-adapted strain to establish a mouse model

To establish a mouse model with the seasonal influenza virus H3N2 mouse-adapted strain, and to describe the molecular mechanism of the adaptation to the change of the virulence of the strain...

2024-04-02

【Animal modeling】-The scavenging effect of arginine antidiuretic hormone on pulmonary edema in rats with acute lung injury

To investigate the effect of arginine antidiuretic hormone (AVP) on pulmonary edema fluid clearance in patients with acute lung injury...

2024-04-02

【Animal modeling】-Effect of cigarette smoke exposure on plasma nicotine and cotinine in male rats

To investigate the internal exposure level of cigarettes in vivo by measuring the plasma nicotine and cotinine contents in smoking rats...

2024-04-02

【Animal Modeling】-Effect of high-fat diet-induced obesity on ovarian function in female reproductive rats

To evaluate the effect of high-fat diet-induced obesity on ovarian function in female rats, and to explore its mechanism...

2024-04-01

【Animal modeling】-Quantitative analysis of liver tumors in BALB/c mutant curly mice based on Image J software

To investigate the differences between BALB/c mutant curly-haired mice and normal BALB/c mice to construct tumor models via portal vein injection, and to establish a quantitative analysis method of tumor images based on Image J software...

2024-04-01

【Animal modeling】-Establishment and applicability evaluation of animal model of pelvic organ prolapse

To establish a rat animal model that can reflect the similar pathological changes of the sacral ligament in patients with pelvic organ prolapse, to explore the effects of increasing the intensity of birth trauma and simulating menopause on the histop...

2024-04-01

【Animal Modeling】-Miniature Pig Obesity Model Induced by High Sugar and High Fat Feed

To investigate the effect of high-fat and high-sugar diet on fat distribution and blood biochemical indexes in Bama miniature pigs...

2024-04-01

【Animal modeling】-Lipopolysaccharide-induced knee joint fibroblast-like synovial cell inflammation model in SD rats and analysis of its characteristics

To establish a primary culture method of normal knee synovial cells in Sprague Dawley (SD) rats and a lipopolysaccharide-induced fibroblast-like synovial cell inflammation model...

2024-04-01

【Animal Modeling】-Comparison of the effect of gene therapy and traditional non-surgical therapy on postpartum stress urinary incontinence model rats

To study the effect of TGF-β1 gene therapy on rat model of postpartum stress urinary incontinence, and to explore the ideal new non-surgical treatment method for the disease...

2024-04-01

【Animal Modeling】-Research on the relationship between tree shrew gallstone model and substance P in digestive tract

To investigate the relationship between the establishment of tree shrew gallstone model and substance P by feeding tree shrew with high cholesterol diet...

2024-04-01

【Animal modeling】-Experimental observation of porcine circovirus type 3 infection in BALB/c mice

To study the infection of porcine circovirus type 3 in BALB/c mice...

2024-03-29

【Animal modeling】- Establishment of SD rat limb ischemia-reperfusion injury model

To introduce an improved method of blocking femoral artery blood flow in vitro, and to establish a simple, controllable and reliable model of limb ischemia-reperfusion injury in rats...

2024-03-28