[Animal Modeling]- Establishment of a Rat Fear Stress Model and Analysis of Its Visual Cognitive Effects

To construct rat models of different degrees of fear stress and explore the impact of fear stress on the visual cognitive ability of LE rats...

2024-03-22

[Animal modeling] - establishment and evaluation of a rat visceral hypersensitivity model induced by plantar electric shock method

To establish a rat visceral hypersensitivity animal model through plantar electric shock and evaluate its effectiveness and advantages...

2024-03-22

【Animal modeling】-Exploratory construction of a rat model of chronic ischemic limb pain

To explore a simple and reliable method to construct a rat model of chronic ischemic limb pain by measuring the mechanical pain threshold, the degree of swelling of the plantar, the skin temperature of the plantar and the local blood flow of the plan...

2024-03-21

【Animal modeling】-The effect of amputation trauma on cardiac electrophysiology, cardiac function and eNOS pathway in rats

To investigate the changes of cardiac electrophysiology and cardiac function after amputation in rats and their relationship with endothelial nitric oxide synthase/nitric oxide (eNOS/NO) pathway...

2024-03-21

【Animal modeling】-Optimization of the establishment of rat interstitial cystitis model induced by intraperitoneal injection of cyclophosphamide

To explore the ideal dose of intraperitoneal injection of cyclophosphamide to establish a rat model of interstitial cystitis...

2024-03-21

【Animal modeling】-Using Matrigel to block the portal vein to establish an improved ALPPS surgery mouse model

To establish a modified two-step hepatectomy mouse model with liver partition and portal vein ligation independent of microsurgical techniques, and to verify its effectiveness in stimulating liver regeneration...

2024-03-21

【Animal Modeling】-Effect of Bushen Yangxue Recipe on Anti-Müllerian Hormone in Rats with Premature Ovarian Failure

To establish a rat model of premature ovarian failure induced by Tripterygium wilfordii polyglycosides, and to study the effect of Bushen Yangxue Recipe on anti-mullerian in rats with premature ovarian failure...

2024-03-21

[Animal model] - Preparation and evaluation of rat model of acute myocardial injury induced by different doses of isoproterenol

To study the effects of different doses of isoproterenol on cardiac function and pathomorphology in rats...

2024-03-21

【Animal Modeling】-Research progress of animal models of vascular cognitive impairment

Vascular cognitive impairment is one of the hot spots of medical research in recent years. The etiology of the disease is complex, and its clinical manifestations include multi-cognitive disorder, memory impairment, and dementia, which seriously affe...

2024-03-21

【Animal Modeling】-The Safety Pharmacological Animal Experiment Evaluation of Tanreqing Injection

To observe the effects of Tanreqing injection on the cardiovascular system, respiratory system and central nervous system of ICR mice in Beagle dogs, and to provide safety experimental data for its clinical use...

2024-03-21

【Animal Modeling】-The changes of cytokines in the process of hepatocellular carcinoma in rats with oxymatrine combined with all-trans retinoic acid

To observe the effect of oxymatrine combined with all-trans retinoic acid in inhibiting the formation of liver cancer in rats induced by diethylnitrosamine (DEN), and to explore its mechanism...

2024-03-21

[Animal modeling]- establishment of a gastric cancer metastasis model based on clinical tumor specimens

To establish a gastric cancer metastasis model based on clinical tumor specimens and provide personalized animal models for the study of gastric cancer metastasis...

2024-03-20

[Animal Modeling] - Establishment of a Rat Fear Stress Model and Analysis of Its Visual Cognitive Effects

To construct rat models of different degrees of fear stress and explore the impact of fear stress on the visual cognitive ability of LE rats...

2024-03-20

[Animal modeling]- establishment and evaluation of a rat visceral hypersensitivity model induced by plantar electric shock method

To establish a rat visceral hypersensitivity animal model through plantar electric shock and evaluate its effectiveness and advantages...

2024-03-20

[Animal modeling] - establishment of a physical fatigue model in mice induced by sleep disturbances at different times

To study the effects of sleep disturbances at different times on physical fatigue in mice, and to provide a stable and reliable animal model for the development of products to alleviate physical fatigue...

2024-03-20

[Animal modeling] - Establishment of chronic renal insufficiency model in mice induced by repeated injection of cisplatin

To establish a C57BL/6 mouse model of chronic kidney disease, explore the changes of tubule injury index and interstitial fibrosis degree with cisplatin modeling dose, and provide animal experimental basis for studying the progress from AKI to CKD...

2024-03-20