[Animal Modeling] - Problems and Strategies in the Preparation of Human Derived Xenotransplantation Models for Gastric Cancer

The establishment of a tumor xenograft model reflecting the clinical characteristics of gastric cancer is of great significance for gastric cancer research. This model has been widely applied in many fields of tumor research, including screening of n...

2024-03-19

[Animal Modeling] - Application of Aseptic Mouse Models in Colorectal Cancer Research

Sterile animal models, especially sterile mouse models, are simple and easy to obtain, providing important tools for studying the complex relationships between microbiota, colorectal tumors, and the body...

2024-03-19

Feasibility Study of Acupuncture Treatment for Chronic Myocardial Ischemia in Small Pig Models

To explore the feasibility of a series of methods for burying needles to treat chronic myocardial ischemia in small pigs with the placement of the Ameroid constrictor ring in the left anterior descending branch during surgery?...

2024-03-19

[Animal Modeling] - Comparative Study on Hepatotoxicity of Matrine and Oxymatrine in Vivo and in Vitro Models

To compare the hepatotoxicity of matrine and oxymatrine, in order to explore their severity and characteristics of toxicity, and to preliminarily elucidate the toxicity mechanism?...

2024-03-19

[Animal modeling] - Abnormal bone and mineral metabolism in adenine induced chronic kidney disease rat model

To observe the biochemical markers of mineral metabolism in a rat model of chronic kidney disease induced by adenine? What are the characteristics of vascular calcification and renal bone disease changes?...

2024-03-19

Establishment and evaluation of an animal model of cyclophosphamide induced premature ovarian failure in rabbits

To compare the methods of establishing animal models of cyclophosphamide induced premature ovarian failure in rabbits under different injection methods, and to find the best modeling method, in order to provide a more suitable experimental model for ...

2024-03-19

[Animal modeling] - Preparation of a highly dynamic septic shock dog model by intravenous injection of Escherichia coli

To prepare a highly dynamic septic shock dog model by intravenous injection of Escherichia coli...

2024-03-18

[Animal modeling] - construction and evaluation of a rat peritoneal adhesion model

Peritoneal adhesion is a product of the body\'s defensive response after peritoneal injury, which can occur between abdominal organs or between organs and the abdominal wall, and can cause varying degrees of intestinal obstruction, chronic pelvic and...

2024-03-18

[Animal modeling] - FTS and NIRF conjugated compounds for imaging and treatment of mouse tumor models

To study the tumor targeting properties of the conjugated compound of farnesylthiosalicylic acid and heptamethylchuanjing near-infrared fluorescent dye, and its application in live imaging, in order to clarify the inhibitory effect of this compound o...

2024-03-18

[Animal modeling] - Comparison of modeling methods for human derived adenomyosis in nude mice

To establish a nude mouse human derived adenomyosis model through different modeling methods, screen out ideal modeling methods, and provide an ideal animal model for studying the pathogenesis and related treatment plans of adenomyosis...

2024-03-18

【Animal modeling】-Intervention effect of electroacupuncture on NF-κBp65 protein in the spinal dorsal horn of rats with diabetic neuralgia

To observe the intervention effect of electroacupuncture on the nuclear transcription factor κBp65 protein in the spinal dorsal horn of rats with diabetic neuralgia, so as to explore the partial analgesic mechanism of electroacupuncture in diabetic n...

2024-03-16

[Animal Modeling] - Preparation Method and Evaluation Index Analysis of Perimenopausal Syndrome Animal Models

To comprehensively analyze the preparation methods of animal models for perimenopausal syndrome that have been reported, compare the advantages and disadvantages of various elements and detection indicators in model preparation, and provide useful re...

2024-03-16

【Animal modeling】-Effect of postconditioning with dezocine on acute lung injury induced by intestinal ischemia-reperfusion in rats

To investigate the effect and possible mechanism of dezocine postconditioning on acute lung injury induced by intestinal ischemia-reperfusion in rats...

2024-03-15

【Animal Modeling】-Research on the standard of abnormal toxicity of Asarum injection preparations detected by mice

To determine the LD50 value of mice intravenously administered with Asarum injection preparation, and to draft the abnormal toxicity inspection standard of this product...

2024-03-15

【Animal Modeling】-Expression of Perilipin in Kidney Tissue of Rats with Diabetic Nephropathy

To observe the characteristics of rat diabetic nephropathy model and the diagnostic value of urinary LN for early DN, and to explore the expression of perilipin in the kidney of DN rats...

2024-03-15

[Animal modeling] - Establishment and evaluation of a mouse model of diabetes lower limb ulcer

To establish and evaluate the mouse model of diabetes lower limb ulcer, reveal the changes of blood flow and pathophysiology in the operative limb of diabetes lower limb ulcer mice, and explore its pathogenesis, so as to provide a basis and reference...

2024-03-14