[Animal modeling] - Changes in synapses in the inner layer of the retina after chronic elevated intraocular pressure in glaucoma animal models

The synapses of retinal ganglion cell dendrites (RGCs) at the axonal terminals of bipolar cells in the inner reticulum layer (IPL). The changes in dendrites and synapses of bipolar cells in the inner retina may severely impair the function of retinal...

2024-03-04

[Animal Modeling] - Evaluation of a Gene Knocked in Mouse Model of Hyperthyroidism, Hypokalemia, and Periodic Paralysis

To establish a hyperthyroidism hypokalemic periodic paralysis model in CaV1.1-R528H mice by knocking in genes and evaluate it...

2024-03-04

[Animal Modeling] - Preparation of a Rat Model of Middle Cerebral Artery Embolism by Carotid Artery Puncture

To compare the timeliness, success rate, and mortality rate of rat middle cerebral artery embolism models prepared by common carotid artery puncture and traditional thread embolization methods...

2024-03-04

[Animal modeling] - Establishment and pathological observation of a rat model of chronic heart failure caused by aortic arch stenosis

To observe the pathological changes in heart failure caused by aortic arch stenosis in rats...

2024-03-04

[Animal Modeling] - How to Establish an Animal Model of Schizophrenia

Schizophrenia is a common severe mental illness in psychiatry, with a high disability rate and one of the most burdensome mental disorders. Its lifetime prevalence rate accounts for about 1% of the entire population...

2024-03-04

[Animal Modeling] - Establishment of an Orthotopic Liver Transplantation Model in Long Clawed Gerbils

To establish a method and technique for establishing an orthotopic liver transplantation model in long clawed gerbils...

2024-03-04

[Animal modeling] - establishment of a mouse heterotopic limb composite tissue transplantation model

To establish a stable mouse model of heterotopic limb composite tissue transplantation...

2024-03-04

[Animal modeling]- Establishment of a rabbit scoliosis model with unilateral transverse process tension spring compression

To establish a rabbit scoliosis model using the unilateral transverse process tension spring compression method...

2024-03-04

[Animal Modeling] - Establishment of an Experimental Model of Stretching Osteogenesis in Rats

To establish a novel method for tibial distraction osteogenesis in SD rats...

2024-03-04

[Animal Modeling] - Establishment and Evaluation of a Constipated Irritable Bowel Syndrome Model with Liver Depression Syndrome

To establish a rat model of superior mesenteric vein thrombosis using ligation method, simulate the pathological process of the disease, and provide basic preparation for studying its pathogenesis and treatment methods...

2024-03-02

[Animal modeling] - establishment of chronic myocardial ischemia model in miniature pigs and application of non-invasive telemetry technology

In response to the shortcomings of previous models of chronic myocardial ischemia in pigs, this study first investigated the mechanism of hyperlipidemia leading to AS and causing coronary artery obstruction or stenosis. A high-fat diet was used to in...

2024-03-02

[Animal modeling]- Application evaluation of continuous glucose monitoring system in rabbit hypoglycemia model

To establish a rabbit hypoglycemia model and evaluate the accuracy and timeliness of subcutaneous continuous glucose monitoring system in hypoglycemia monitoring...

2024-03-02

[Animal modeling] - comparative analysis of three models of chicken embryo chorioallantoic membrane transplantation tumors

To compare the growth of three different cancer cell lines on the chorioallantoic membrane of chicken embryos, select the best transplantation cancer cell line, establish a transplantation tumor model, and observe its biological characteristics...

2024-03-02

[Animal modeling] - Application of targeted near-infrared fluorescent dyes in liver cancer model research

To explore the application of the near-infrared fluorescent dye IR-783 of heptamethrin in imaging research of liver cancer models, and analyze the molecular mechanism of the dye targeting tumor cells...

2024-03-02

[Animal modeling] - Prophylactic administration of all trans retinoic acid can alleviate inflammation in rheumatoid arthritis model rats

To explore the effects of all trans retinoic acid (ATRA) on the joint tissue structure, serum expression levels of inflammatory cytokines, and expression levels of cartilage injury related proteins during the formation phase of type II collagen (CIA)...

2024-03-02

Construction of an animal model of chronic simple lichen in the external genitalia of SD rats and expression of protease activated receptor 2

To establish an animal model of chronic simple lichen in the external genitalia of SD rats, study the expression of protease activated receptor 2 in the model rat external genitalia skin lesions, and provide an ideal animal model for LSC...

2024-03-02