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【Animal Modeling】-Protective effect of Shenmai on brain tissue of mice with acute cerebral infarction and its related mechanism

【Animal Modeling】-Protective effect of Shenmai on brain tissue of mice with acute cerebral infarction and its related mechanism

To study the protective effect of Shenmai injection on the brain tissue of mice with acute cerebral infarction and to preliminarily explore its possible mechanism...

2023-12-28
【Animal Modeling】-Inhibitory effect of cytomegalovirus on some immune indexes in mice implanted with polymethyl methacrylate

【Animal Modeling】-Inhibitory effect of cytomegalovirus on some immune indexes in mice implanted with polymethyl methacrylate

To study the inhibitory effect of cytomegalovirus on the immune response of mice implanted with polymethyl methacrylate...

2023-12-28
【Animal modeling】-Establishment of cynomolgus monkey muscle atrophy model

【Animal modeling】-Establishment of cynomolgus monkey muscle atrophy model

To establish an animal model of cynomolgus monkey muscle atrophy by restricting lower extremity activities, and to establish a method for evaluating the model?...

2023-12-27
【Animal modeling】-Protective effect of Nrf2 antioxidant pathway in CCl4-induced acute liver injury in rats

【Animal modeling】-Protective effect of Nrf2 antioxidant pathway in CCl4-induced acute liver injury in rats

To study the protective effect of Nrf2 oxidative damage pathway in CCl4-induced acute liver injury in rats...

2023-12-27
【Animal Modeling】-Effect of Shenzhiling Oral Liquid on Early Hippocampal Synapse and Myelin Changes in App/Ps1 Double Transgenic Mice

【Animal Modeling】-Effect of Shenzhiling Oral Liquid on Early Hippocampal Synapse and Myelin Changes in App/Ps1 Double Transgenic Mice

To observe the early neuroprotective effect of Shenzhiling oral liquid on AD mice by observing the ultrastructure of myelin sheath and synapse in the CA1 region of the hippocampus and the special staining changes of myelin sheath in 3-month-old App/P...

2023-12-26
【Animal modeling】-Determination of main biological characteristics of hACE2-KI/NIFDC mice

【Animal modeling】-Determination of main biological characteristics of hACE2-KI/NIFDC mice

To determine the biological characteristics of self-bred hACE2-KI/NIFDC transgenic mice...

2023-12-26
【Animal Modeling】-Hydrogen peroxide-induced changes in isolated rat uterine ligament fibroblasts

【Animal Modeling】-Hydrogen peroxide-induced changes in isolated rat uterine ligament fibroblasts

To investigate the effect and possible mechanism of oxidative stress on the proliferation, apoptosis, collagen synthesis and inflammatory factor expression of uterine ligament fibroblasts...

2023-12-25
【Animal modeling】-Protective effect of liraglutide on stress-stressed chronic heart failure in rats

【Animal modeling】-Protective effect of liraglutide on stress-stressed chronic heart failure in rats

To study the effect and mechanism of liraglutide on cardiac function in pressure-stressed chronic heart failure rats...

2023-12-25
【Animal Modeling】-Establishment of a mouse model of chronic renal insufficiency induced by repeated injection of cisplatin

【Animal Modeling】-Establishment of a mouse model of chronic renal insufficiency induced by repeated injection of cisplatin

To construct a C57BL/6 mouse model of chronic kidney disease, and to explore the changes of its tubular injury indexes and interstitial fibrosis with the dose of cisplatin, so as to provide an animal experimental basis for studying the progression fr...

2023-12-22
【Animal Modeling】-VEGF-A Inhibitor sFLT-1 Improves Renal Function in Type 1 Diabetic Mice

【Animal Modeling】-VEGF-A Inhibitor sFLT-1 Improves Renal Function in Type 1 Diabetic Mice

To investigate whether the VEGF-A inhibitor sFLT-1 can reverse the renal damage in type 1 diabetic mice by inhibiting the activation and inflammatory response of vascular endothelial cells...

2023-12-22
【Animal Modeling】-Discussion on the Selection of Two Positive Substances in Guinea Pig Active Systemic Allergy Test

【Animal Modeling】-Discussion on the Selection of Two Positive Substances in Guinea Pig Active Systemic Allergy Test

To compare the effects of two positive substances, human serum albumin and ovalbumin, on active systemic allergy in guinea pigs, so as to provide a better positive control for allergy tests...

2023-12-22
【Animal modeling】-Establishment of a rat model of uterine fibroids-bearing transplanted tumor

【Animal modeling】-Establishment of a rat model of uterine fibroids-bearing transplanted tumor

To establish a rat model of uterine fibroids-bearing tissue transplanted by tissue transplantation in immunosuppressive rats, and to provide a new animal model for the study of uterine fibroids...

2023-12-22
【Animal Modeling】-Establishment and preliminary analysis of the cynomolgus monkey model of hyperlipidemia

【Animal Modeling】-Establishment and preliminary analysis of the cynomolgus monkey model of hyperlipidemia

To establish a hyperlipidemia cynomolgus monkey model with similar characteristics of human diseases, and to provide an ideal animal model for the development of lipid-lowering drugs (especially biological lipid-lowering drugs)...

2023-12-21
【Animal Modeling】-Intestinal fistula operation method abdominal cavity infection model in rats

【Animal Modeling】-Intestinal fistula operation method abdominal cavity infection model in rats

Breeding method Adult male rats weighing 250 to 270g are used, and the abdominal infection group undergoes intestinal fistula surgery...

2023-12-21
【Animal Modeling】-Effects of MED1 deletion in macrophages on blood glucose levels and insulin resistance in mice

【Animal Modeling】-Effects of MED1 deletion in macrophages on blood glucose levels and insulin resistance in mice

To study the regulatory role of macrophage MED1 in the occurrence of insulin resistance...

2023-12-21
[Animal modeling] - Acute liver injury model induced by concanavalin A

[Animal modeling] - Acute liver injury model induced by concanavalin A

BALB/c mice, weighing 20-30g, regardless of gender; Medications: Concanavalin A (ConA), PBS...

2023-12-20