[Animal modeling] - Establishment of animal model of dysuricemia type hyperuricemia

To explore a reliable method to establish a rat model of dysuricemia, and lay a foundation for the study of the pathogenesis of dysuricemia and the optimization of the treatment plan...

2024-11-06

【Animal Modeling】-Effect of two-color coreopsis alcohol extract on intestinal flora of type 2 diabetic mice

To explore the possible link between the alcoholic extract of coreopsis bicolor, intestinal flora and type 2 diabetes mellitus...

2024-11-04

[Animal modeling] Preparation and evaluation of Parkinson\\\\

To establish a stable Parkinson\\\\\\\'s disease model in C57BL/6 mice induced by 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) and evaluate the behavior of the model...

2024-11-04

【Animal Modeling】-Establishment of a mouse model of chronic thrombus induced by carrageenan

To screen the conditions of chronic thrombosis mouse model by treating mice with different concentrations of carrageenan solution by continuous intraperitoneal injection...

2024-11-04

[Animal modeling] - Expression and significance of thrombomodulin in deep vein thrombosis model of rats

To observe the expression and significance of thrombomodulin (TM) in the natural evolution of deep vein thrombosis (DVT) in rats...

2024-11-01

[Animal modeling] - Taurine has no protective effect on corneal endothelial cells in rats injured by Benzalkonium chloride

To observe the protective effect of 2% Taurine on corneal endothelial cells injured by Benzalkonium chloride in rats...

2024-10-31

【Animal modeling】-Protective effect of ulinastatin on acute lung injury in severe heatstroke mice

To investigate the protective effect of ulinastatin on acute lung injury in mice with severe heat stroke...

2024-10-31

【Animal modeling】-Preliminary study on the establishment of quail gout model with high protein and high calcium diet combined with restricted drinking water

By simulating the clinical high-protein and high-calcium diet to induce gout in Difak quail, the method of establishing the gout model of quail was preliminarily discussed, and the basis for the research on the pathogenesis of gout and the screening...

2024-10-31

【Animal Modeling】-TNF-α humanized mouse model of Listeria monocytogenes infection

To evaluate the change of the host\\\\\\\\\\\\\\\'s susceptibility to Listeria monocytogenes infection after TNF-α monoclonal antibody intervention...

2024-10-31

【Animal modeling】-Effect of hypoxia on the expressions of drug transporters MDR1 and MRP2 in rats

To study the effects of simulated rapid altitude hypoxia on some physiological indexes and the expressions of MDR1 and MRP2 efflux drug transporters in the small intestine, liver and kidney of rats, and to preliminarily explore the effect of high alt...

2024-10-31

[Animal modeling] - Prophylactic administration of all trans retinoic acid can alleviate inflammation in rheumatoid arthritis model rats

To explore the effects of all trans retinoic acid (ATRA) on the joint tissue structure, serum expression levels of inflammatory cytokines, and expression levels of cartilage injury related proteins during the formation phase of type II collagen (CIA)...

2024-10-31

【Animal modeling】-Establishment and analysis of a cynomolgus monkey model of hyperlipidemia

To establish a cynomolgus monkey model of hyperlipidemia...

2024-10-30

【Animal modeling】-Effect of ligustrazine on extracellular regulated protein kinase pathway in collagen-induced arthritis rats

To investigate the effect of ligustrazine on extracellular regulated protein kinase pathway in collagen-induced arthritis rats...

2024-10-30

[Animal Modeling] - Thyroidectomy Method for Kidney Yang Deficiency Animal Model

Adult rats were anesthetized, with skin incision, muscle dissection, bilateral thyroid separation and excision, and muscle and skin suturing. Observe the general condition of rats, test left ventricular function and thyroid function, euthanize animal...

2024-10-30

[Animal modeling]-The unique metabolic activation of adipose tissue in obese patients promotes inflammation

Macrophages accumulate in adipose tissue, trigger chronic low-grade inflammation, and promote the development of systemic insulin resistance...

2024-10-30

[Animal Modeling] - Adrenalectomy for Kidney Yang Deficiency Animal Model

Adult rats were anesthetized with ether and bilateral adrenalectomy was performed. After surgery, they were raised in plastic mouse boxes with shavings as bedding, kept at room temperature of 21-25 ℃, and replaced with glucose physiological saline fo...

2024-10-30