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【Animal modeling】-Effect of Ghrelin on the expression of DKK-1 in the hippocampus and learning and memory function of diabetic rats

【Animal modeling】-Effect of Ghrelin on the expression of DKK-1 in the hippocampus and learning and memory function of diabetic rats

To observe the expression changes of Ghrelin on DKK-1 and WNT signaling pathways in diabetic rats, and to explore the mechanism involved in learning and memory function...

2022-05-27
【Animal Modeling】- Improvement of the method of preventing the displacement of the implanted dilator in the sarcoma and deep fascia of the experimental rabbit

【Animal Modeling】- Improvement of the method of preventing the displacement of the implanted dilator in the sarcoma and deep fascia of the experimental rabbit

To investigate the method of preventing the displacement of the implanted dilator in the sarcoid and deep fascia of rabbits...

2022-05-27
【Animal modeling】-Effect of Bushen Cuovv Decoction on ovarian morphology and sex hormones in polycystic ovary syndrome model rats

【Animal modeling】-Effect of Bushen Cuovv Decoction on ovarian morphology and sex hormones in polycystic ovary syndrome model rats

To explore the effect of Bushen Cuovary Decoction on sex hormone, anti-Müllerian hormone and ovarian morphology in polycystic ovary syndrome model rats, and to explore the treatment of polycystic ovary syndrome (PCOS) by Bushen Cuovvary Decoction mec...

2022-05-27
【Animal modeling】-Effect of astragaloside Ⅱ on IL-21/STAT3 pathway and airway inflammation in juvenile asthmatic rats

【Animal modeling】-Effect of astragaloside Ⅱ on IL-21/STAT3 pathway and airway inflammation in juvenile asthmatic rats

To investigate the effect of astragaloside Ⅱ on interleukin-21 ( IL-21 ) / signal transducer and activator of transcription 3 ( STAT3 ) pathway and airway inflammation in juvenile asthmatic rats...

2022-05-27
【Animal modeling】-PCR detection and analysis of various bacteria in experimental rats and mice

【Animal modeling】-PCR detection and analysis of various bacteria in experimental rats and mice

To investigate the bacterial carriage status of rats and mice in Shanghai laboratory animal production facilities...

2022-05-26
【Animal Modeling】-A comparative study of in situ liver cancer dynamic imaging and pathology in nude mice

【Animal Modeling】-A comparative study of in situ liver cancer dynamic imaging and pathology in nude mice

To dynamically monitor tumor growth in nude mice after orthotopic liver cancer modeling and to compare it with pathology, so as to determine the appropriate period of intervention therapy...

2022-05-26
【Animal modeling】-Characteristics of liver pathological damage in db/db mice with spontaneous type 2 diabetes

【Animal modeling】-Characteristics of liver pathological damage in db/db mice with spontaneous type 2 diabetes

To dynamically observe the pathological changes and characteristics of the liver of db/db mice with spontaneous type 2 diabetes mellitus, and to provide the basic theory and experimental basis for the experimental study of using the liver of db/db mi...

2022-05-26
【Animal Modeling】-Comparison of Two Staining Methods for Rat Vaginal Smears

【Animal Modeling】-Comparison of Two Staining Methods for Rat Vaginal Smears

To find a simple staining method for determining the four stages of the rat estrous cycle by staining the vaginal smears of SD female rats to observe the cell morphology...

2022-05-26
【Animal modeling】-Establishment and identification of vitamin D receptor gene knockout mouse strain

【Animal modeling】-Establishment and identification of vitamin D receptor gene knockout mouse strain

To explore the optimal breeding method and identification method of vitamin D receptor (VDR) knockout mice, and to provide animal models for further study of VDR function and related diseases...

2022-05-26
【Animal Modeling】-Discussion on the Sequence Scheme of Reducing Image Respiration and Heartbeat Artifacts in In vivo Thoracic Scanning of Rats

【Animal Modeling】-Discussion on the Sequence Scheme of Reducing Image Respiration and Heartbeat Artifacts in In vivo Thoracic Scanning of Rats

To develop a sequence that reduces image breathing and heartbeat artifacts in 256-slice spiral CT rat in vivo chest CT scans...

2022-05-26
【Animal Modeling】-Effect of nicotine on changes of pain threshold plasticity and cardioprotection in rats with myocardial infarction

【Animal Modeling】-Effect of nicotine on changes of pain threshold plasticity and cardioprotection in rats with myocardial infarction

To observe the plastic changes of pain threshold in rats with myocardial infarction, and to explore the effect of nicotine on visceral pain and whether it has a protective effect on ischemic myocardium...

2022-05-26
[Animal Modeling]-Blocking the PD1/PD-L1 pathway mediated by macrophages inhibits the recurrence of tuberculosis in mice

[Animal Modeling]-Blocking the PD1/PD-L1 pathway mediated by macrophages inhibits the recurrence of tuberculosis in mice

Functional PD? Using L1 (programmed cell death ligand 1, PD 2 L1) monoclonal antibody, PD1/PD 3. To study the mechanism of immune intervention and relapse after tuberculosis treatment by blocking the L1 pathway...

2022-05-26
【Animal Modeling】-Effect of psycho-dependent heroin on embryonic development and Bax expression in brain tissue of rats

【Animal Modeling】-Effect of psycho-dependent heroin on embryonic development and Bax expression in brain tissue of rats

To investigate the effect of heroin, a psychotropic substance, on the development of embryonic rats and the expression of Bax in the brain...

2022-05-26
【Animal Modeling】-Effect of a single intraosseous injection of low-dose simvastatin on angiogenesis after myocardial infarction in rats

【Animal Modeling】-Effect of a single intraosseous injection of low-dose simvastatin on angiogenesis after myocardial infarction in rats

To study the effect of intraosseous local single injection of low-dose simvastatin on angiogenesis and cardiac function in rats after myocardial infarction...

2022-05-26
【Animal Modeling】-Effects of IL-27 and its receptors on the proliferation and transformation of lung fibroblasts

【Animal Modeling】-Effects of IL-27 and its receptors on the proliferation and transformation of lung fibroblasts

To investigate the effects of IL-27 and its receptor (WSX-1) on the proliferation, transformation and collagen synthesis of mouse lung fibroblasts induced by TGF-β1...

2022-05-26
【Animal Modeling】-Minocycline inhibits the hyperpolarization-activated current of glial neurons in the dorsal horn of rat spinal cord

【Animal Modeling】-Minocycline inhibits the hyperpolarization-activated current of glial neurons in the dorsal horn of rat spinal cord

To study the effect of minocycline on the hyperpolarization-activated current (Ih) of colloidal (SG) neurons in the spinal dorsal horn of rats...

2022-05-26