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To construct stably overexpressed miR-31 transgenic mice, to detect the expression changes of miR-31 in major tissues and organs, and to provide qualified tool mice for the application of miR-31 overexpression in vivo...
2022-05-18To investigate the related mechanism of hypertonic saline treatment in reducing cerebral edema in rats with cerebral hemorrhage...
2022-05-18To investigate the effect of astragalus injection (AI) on the apoptosis of hippocampal neurons in hypoxia-hypoglycemia/reoxygenation and reglycemia (H/R) rats under the action of Bcl-2 inhibitor (TW-37)...
2022-05-18To study the effect of acute exercise on myocardial miRNA-30a and the expression of autophagy-related genes in rats, and to explore the regulatory mechanism of miRNA-30a on myocardial autophagy activity in different recovery periods after exercise...
2022-05-18To observe the therapeutic effect of Guanxinning Tablets on chronic heart failure (CHF) mice, and to explore its action pathway from myocardial cell apoptosis and related cell signaling pathways, so as to provide experimental basis for the clinical a...
2022-05-17To observe the changes in the structure and function of the immune system in naturally aged SD rats, and to explore the possible mechanisms?...
2022-05-17To study whether ventricular extracellular matrix (ECM) can promote the differentiation of cardiomyocyte-derived cardiac stem cells (CDC) implanted into myocardial tissue of myocardial infarction into cardiomyocytes, vascular endothelial and vascular...
2022-05-17To observe the expression of phosphorylated calcineurin II (p-CaMK II) in the dorsal root ganglia of diabetic neuropathic pain model rats at different stages...
2022-05-17Taking SD rats as the research object, to explore the effect of histamine on neurons in the hippocampal C1 area and the behavior of depression rats?...
2022-05-17To construct lymphocyte activation gene ￣3 (Lag￣3) knockout mice, and to preliminarily analyze the effect of Lag￣3 gene knockout on the phenotype of mice, so as to provide an animal model for subsequent in vivo functional studies of Lag￣3...
2022-05-17To study the effect of different doses of N-ethyl-N-nitrosourea (ENU) and cyclophosphamide (CP) on the deletion rate of ankyrin CD59 on the peripheral blood red blood cell surface of SD rats, and to optimize the Pig-a gene mutation test Detection met...
2022-05-17To establish a rabbit model of steroid-induced necrosis of the femoral head, and to evaluate the repairing effect of Taohong Siwu Decoction (THSWD) on the microscopic bone structure damage of SIONFH combined with high-resolution MRI and micro-CT...
2022-05-17To investigate the effect of intraperitoneal injection of human tumor HepG2 cells on fetal mouse growth and development in pregnant mice...
2022-05-17To explore the effects of different doses of icariin on rats with experimental IgA nephropathy, and to study its related mechanism...
2022-05-17To determine the basic biological indicators of SPF CBA/CaJ mice, and to lay a foundation for better use of this strain of mice for biomedical research...
2022-05-16To analyze the structure and composition of E. coli bacteria in tree shrew by high-throughput sequencing technology...
2022-05-16