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【Animal Modeling】-How to establish a stable cerebral infarction model of middle cerebral artery in rats

【Animal Modeling】-How to establish a stable cerebral infarction model of middle cerebral artery in rats

To explore the feasibility of using laser Doppler blood flow monitoring technology to establish a stable model of middle cerebral artery occlusive cerebral infarction (middle cerebral artery occlusion, MCAO) in rats...

2021-08-02
[Animal Modeling]-A rat model of chronic heart failure caused by aortic arch stenosis

[Animal Modeling]-A rat model of chronic heart failure caused by aortic arch stenosis

Observe the pathological changes of rat heart failure caused by aortic arch stenosis...

2021-07-29
Rare human diseases found in dogs may be used as animal model studies

Rare human diseases found in dogs may be used as animal model studies

According to a study by Michigan State University, severe pulmonary hypertension, a rare disease found in dogs, has been classified as a human lung disease...

2021-07-29
【Animal Modeling】-Why build a ZDF rat model of diabetes and coronary heart disease?

【Animal Modeling】-Why build a ZDF rat model of diabetes and coronary heart disease?

Construction of a rat model of type 2 diabetes with coronary heart disease...

2021-07-29
【Animal Modeling】-Establishment of Inducible Liver Injury Model in Alb-cre/DTR Mice

【Animal Modeling】-Establishment of Inducible Liver Injury Model in Alb-cre/DTR Mice

Establish an Alb-cre/DTR double transgenic mouse model, carry out related phenotype analysis, and establish an induced liver injury model on this basis, for liver disease related research...

2021-07-29
【Animal Modeling】-Research progress on the relationship between adult growth hormone deficiency animal models and bone metabolism

【Animal Modeling】-Research progress on the relationship between adult growth hormone deficiency animal models and bone metabolism

Explore several methods for establishing adult growth hormone deficiency animal models, and provide an excellent model for experimental research and treatment of abnormal bone metabolism caused by growth hormone deficiency...

2021-07-29
【Animal Modeling】-Comparison of three strains of mouse influenza virus aerosol infection models

【Animal Modeling】-Comparison of three strains of mouse influenza virus aerosol infection models

Infect three strains of mice through aerosol challenge to produce aerosols, analyze the characteristics of the three strains of mouse influenza model, and compare the infection differences of the three strains of mice during the infection process...

2021-07-29
【Animal Modeling】-Establishment and evaluation of murine sepsis model

【Animal Modeling】-Establishment and evaluation of murine sepsis model

Establish and evaluate a mouse sepsis model, study the pathogenesis of sepsis, and provide model animals for the development of anti-inflammatory drugs...

2021-07-29
[Animal modeling]-Phenotypic transformation of bladder smooth muscle in diabetic rats

[Animal modeling]-Phenotypic transformation of bladder smooth muscle in diabetic rats

Detect the expression levels of bladder smooth muscle contraction markers and the main regulatory gene myocardin in diabetic SD rats 9 weeks after the establishment of streptozotocin to understand whether the bladder smooth muscle of diabetic rats ha...

2021-07-29
【Animal Modeling】-Establishment and identification of paclitaxel-resistant lung transplanted tumor model in orthotopic mice

【Animal Modeling】-Establishment and identification of paclitaxel-resistant lung transplanted tumor model in orthotopic mice

To establish an animal model of orthotopic lung transplantation for paclitaxel-resistant tumors to study the mechanism of drug resistance...

2021-07-28
【Animal Modeling】-Establishment of a rat model of chronic hyperuricemia with renal damage

【Animal Modeling】-Establishment of a rat model of chronic hyperuricemia with renal damage

Establish a rat model of chronic hyperuricemia nephropathy, and provide model tools for the development of anti-chronic hyperuricemia nephropathy drugs...

2021-07-28
【Animal Modeling】-Preliminary establishment of rat transplantation model of human glioma

【Animal Modeling】-Preliminary establishment of rat transplantation model of human glioma

It is the first time to establish a rat xenograft model of human glioma using immunosuppressive agents, providing an ideal experimental tool for clinical and basic research...

2021-07-28
【Animal modeling】-CD32 expression characteristics in a rhesus monkey model of latent AIDS infection

【Animal modeling】-CD32 expression characteristics in a rhesus monkey model of latent AIDS infection

Establish a latent infection model of Rhesus monkey SIVmac239, study the expression characteristics of CD32 in resting, activated and/or memory CD4+ T cell subsets, and analyze its potential as a marker of AIDS latent pool...

2021-07-28
[Animal Modeling]-The mechanism of miR-20a-5p regulating VEGF pathway in a mouse model of oxygen-induced retinopathy

[Animal Modeling]-The mechanism of miR-20a-5p regulating VEGF pathway in a mouse model of oxygen-induced retinopathy

Explore the mechanism of microRNA (miR)-20a-5p regulating the vascular endothelial growth factor (VEGF) pathway of oxygen-induced retinopathy (OIR) in mice...

2021-07-28
【Animal Modeling】-Research Progress of Hollow Fiber Tumor Model

【Animal Modeling】-Research Progress of Hollow Fiber Tumor Model

The hollow fiber tumor model or HollowFiberAssay (HFA) is a new type of anti-cancer drug pre-screening model designed by the National Cancer Institute (NCI), which is simple, fast, accurate, simple and feasible....

2021-07-28
【Animal Modeling】-Analysis of the application of 274 rheumatoid arthritis animal models based on data mining

【Animal Modeling】-Analysis of the application of 274 rheumatoid arthritis animal models based on data mining

Study the modeling elements of animal models of rheumatoid arthritis, improve the success rate of modeling, and provide methodological references for evaluating the efficacy of tested drugs...

2021-07-28