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【Animal Modeling】-A new mouse model of severe heart disease in children

【Animal Modeling】-A new mouse model of severe heart disease in children

Severe childhood restrictive cardiomyopathy is a condition in which the muscles of the myocardial wall become stiff and prevent the heart from filling up with blood normally....

2021-07-28
【Animal Modeling】-Establish an animal model of human intestinal flora of Alzheimer\'s disease

【Animal Modeling】-Establish an animal model of human intestinal flora of Alzheimer\'s disease

Fecal bacterial transplantation was used to obtain human intestinal flora of Alzheimer\'s disease model mice through oral route, and the model was evaluated through bioinformatics, histopathology and other methods...

2021-07-28
【Animal Modeling】-Establishment of a mouse model of chronic thrombosis induced by carrageenan

【Animal Modeling】-Establishment of a mouse model of chronic thrombosis induced by carrageenan

The mice were treated by continuous intraperitoneal injection of different concentrations of carrageenan solution, and the disease condition of the mouse model of chronic thrombosis was screened....

2021-07-28
【Animal Modeling】-Establishment of a rat model of coronary heart disease combined with Qi deficiency and blood stasis syndrome

【Animal Modeling】-Establishment of a rat model of coronary heart disease combined with Qi deficiency and blood stasis syndrome

Establish a compound model of the relationship between pathology, etiology, coronary heart disease (CHD) Qi deficiency and blood stasis syndrome combined with tongue symptoms and the relationship between prostacyclin (PGI2) and thromboxane A2 (TXA2)...

2021-07-27
【Animal Modeling】-Ovalbumin (OVA) sensitization combined with smoking method to establish cough variant asthma guinea pig model

【Animal Modeling】-Ovalbumin (OVA) sensitization combined with smoking method to establish cough variant asthma guinea pig model

Try to use ovalbumin in combination with smoking to establish a more similar guinea pig CVA model...

2021-07-27
【Animal Modeling】-Experimental study of SD rat portal hypertension animal model prepared by ligation of the left branch

【Animal Modeling】-Experimental study of SD rat portal hypertension animal model prepared by ligation of the left branch

To explore whether a simple ligation of the left portal vein can form a stable portal hypertension, and whether nitric oxide plays a corresponding role...

2021-07-27
【Animal Modeling】-STZ Research Progress on the Influencing Factors of Diabetic Rat Models

【Animal Modeling】-STZ Research Progress on the Influencing Factors of Diabetic Rat Models

Diabetes has become a worldwide epidemic, and its incidence is increasing year by year. In order to further study the causes of DM and formulate more effective prevention and treatment plans, researchers need a stable and reproducible animal model si...

2021-07-27
【Animal Modeling】-Research progress on the establishment of preeclampsia rat mouse model

【Animal Modeling】-Research progress on the establishment of preeclampsia rat mouse model

Pre-eclampsia (PE) is a unique pregnancy disease and one of the main causes of morbidity and death in pregnant women and perinatal infants...

2021-07-27
【Animal Modeling】-Establishment and applicability evaluation of animal model of pelvic organ prolapse

【Animal Modeling】-Establishment and applicability evaluation of animal model of pelvic organ prolapse

Establish a rat animal model that can reflect the similar pathological changes of the sacral ligament in patients with pelvic organ prolapse, and explore the effects of increased labor intensity and simulated menopause on the pathological changes of ...

2021-07-27
【Animal Modeling】-Characteristics of the pathological process of cardiac structure and function in a pressure-overloaded heart failure mouse model

【Animal Modeling】-Characteristics of the pathological process of cardiac structure and function in a pressure-overloaded heart failure mouse model

Establish a mouse model of heart failure, and use ultrasound images and pathological techniques to comprehensively evaluate the characteristic changes in cardiac function and structure during the onset of disease...

2021-07-27
【Animal Modeling】-Research Progress of Laminopathy Mouse Model

【Animal Modeling】-Research Progress of Laminopathy Mouse Model

The LMNA gene encodes type A lamin (lamin), and its mutation leads to a series of complex and diverse genetic diseases...

2021-07-27
[Animal modeling]-Carbon tetrachloride induces inbred strain C57BL/6 mice to establish liver fibrosis model

[Animal modeling]-Carbon tetrachloride induces inbred strain C57BL/6 mice to establish liver fibrosis model

Compare the inducing effect of different doses of carbon tetrachloride on the self-bred C57BL/6 mouse liver cirrhosis model, and establish a stable liver cirrhosis model...

2021-07-27
【Animal Modeling】-Establishment and Evaluation of Rabbit Knee Osteoarthritis Model

【Animal Modeling】-Establishment and Evaluation of Rabbit Knee Osteoarthritis Model

To establish a rabbit knee osteoarthritis model and evaluate it through rabbit cartilage defects...

2021-07-27
【Animal Modeling】-Establishment of psychiatric dependence drug addiction model and expression of Bax gene in cerebellum

【Animal Modeling】-Establishment of psychiatric dependence drug addiction model and expression of Bax gene in cerebellum

To study the effect of psychotropic drugs (heroin) on Bax gene expression in the cerebellum of poisoned rats, and establish it with a continuous dose increase method....

2021-07-27
【Animal Modeling】-Improvement and evaluation of the establishment method of neonatal rat necrotizing enterocolitis model

【Animal Modeling】-Improvement and evaluation of the establishment method of neonatal rat necrotizing enterocolitis model

Improve and compare the methods of establishing necrotizing enterocolitis animal models commonly used at home and abroad, and clarify simple and effective NEC modeling methods...

2021-07-26
【Animal Modeling】-Analysis of the preparation and comparison of animal models of facial paralysis

【Animal Modeling】-Analysis of the preparation and comparison of animal models of facial paralysis

Search the related literature of different models of facial paralysis animals, analyze the advantages and disadvantages of various model preparation methods, and explore the preparation methods suitable for different research types, so as to provide ...

2021-07-26