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【Animal Modeling】-Preparation method of long-term stable SD rat type 2 diabetes model

【Animal Modeling】-Preparation method of long-term stable SD rat type 2 diabetes model

Explore how to prepare a rat model of diabetes induced by high-fat diet combined with streptozotocin (STZ) to provide a stable animal model of diabetes for clinical research...

2021-07-26
【Animal Modeling】-Establishment of long-term depression mouse model and observation of behavioral and neuropathological characteristics

【Animal Modeling】-Establishment of long-term depression mouse model and observation of behavioral and neuropathological characteristics

Establish a new type of long-term depression model mouse, and compare the advantages and disadvantages of this mouse with the general depression mouse model...

2021-07-26
【Animal Modeling】-Comparative study on establishing mouse models of allergic conjunctivitis under different conditions

【Animal Modeling】-Comparative study on establishing mouse models of allergic conjunctivitis under different conditions

Establish mouse models of allergic conjunctivitis under different antigens, different excitatory pathways, and different ages, compare immune response status, feel the best mouse models of allergic conjunctivitis, and screen crop conditions...

2021-07-26
The establishment of a new type of hyperlipidemia susceptible (WSHc) rat model of non-alcoholic fatty liver disease and the study of its pathological characteristics

The establishment of a new type of hyperlipidemia susceptible (WSHc) rat model of non-alcoholic fatty liver disease and the study of its pathological characteristics

Use new hyperlipidemia sensitive rats to establish a non-alcoholic fatty liver disease model, observe changes in blood biochemical indicators and pathological properties, explore its application and scientific research value, and provide new options ...

2021-07-26
【Animal Modeling】-Nude mouse model construction of clear cell renal carcinoma and research on the sensitivity of targeted drugs

【Animal Modeling】-Nude mouse model construction of clear cell renal carcinoma and research on the sensitivity of targeted drugs

Use patient-derived clear cell renal cell carcinoma (ccRCC) cells (patient-derived cells, PDC) to detect the sensitivity of ccRCCPDC to molecular targeted drugs for clinical diagnosis and treatment and experimental evidence...

2021-07-26
【Animal Modeling】-Research Progress on Animal Models of Parkinson\'s Disease

【Animal Modeling】-Research Progress on Animal Models of Parkinson\'s Disease

Parkinson\'s disease (PD) is a neurodegenerative disease that seriously endangers human health...

2021-07-26
【Animal Modeling】-Research Progress of Miniature Pig Atherosclerosis Model

【Animal Modeling】-Research Progress of Miniature Pig Atherosclerosis Model

Miniature pigs are very similar to humans in terms of arterial anatomy and physiology, and are currently the most ideal model for studying atherosclerosis (AS) related diseases...

2021-07-26
【Animal Modeling】-Research progress in the construction of hemophilia arthropathy model

【Animal Modeling】-Research progress in the construction of hemophilia arthropathy model

Hemophilic arthropathy is a debilitating disease caused by spontaneous intra-articular hemorrhage and recurrent intra-articular hematoma. The main clinical manifestations are chronic pain, joint damage and poor quality of life....

2021-07-26
【Animal Modeling】-The effect of high-fat feed feeding time on type 2 diabetic nephropathy rat model

【Animal Modeling】-The effect of high-fat feed feeding time on type 2 diabetic nephropathy rat model

How to study the effect of different high-fat diet feeding time on blood glucose, insulin resistance index (HOMA-IR) and urinary albumin excretion rate (UAER) in type 2 diabetic nephropathy (DN) rat models?...

2021-07-22
[Animal Modeling]-Effect of Qingzao Jiufei Decoction and its decomposition agent on inflammation-related factors in the lungs of mice infected with Mycoplasma pneumoniae

[Animal Modeling]-Effect of Qingzao Jiufei Decoction and its decomposition agent on inflammation-related factors in the lungs of mice infected with Mycoplasma pneumoniae

TNF-α in the serum of mice infected with Mycoplasma pneumonia (MP)? INF-γ content and MPN372? P1? To explore the effect of Qingzao Jiufei Decoction (QJD) and its degradation products on lung tissues expressing AQP5, the molecular mechanism of MP infe...

2021-07-22
【Animal Modeling】-The effect of Jin Siwei on the brain cholinergic system of mice with memory impairment caused by scopolamine

【Animal Modeling】-The effect of Jin Siwei on the brain cholinergic system of mice with memory impairment caused by scopolamine

To establish a memory disorder model of scopolamine and use traditional Chinese medicine compound Jin Shen to observe the effect of Jin Shen on the behavior and cholinergic system of mice with memory impairment caused by scopolamine...

2021-07-22
【Animal modeling】-Comparison of dopamine content in the lateral geniculate body of guinea pigs with flash-induced myopia and form-deprivation myopia

【Animal modeling】-Comparison of dopamine content in the lateral geniculate body of guinea pigs with flash-induced myopia and form-deprivation myopia

Observe the changes of dopamine (DA) content in the lateral geniculate body in guinea pig stroboscopic myopia and deprivation myopia models, and conduct a comparative analysis to preliminarily explore the central causes of various myopia models...

2021-07-22
【Animal Modeling】-The effect of estrogen and progesterone on the induced differential expression of αvβ3 in bovine endometrial epithelial cells in vitro

【Animal Modeling】-The effect of estrogen and progesterone on the induced differential expression of αvβ3 in bovine endometrial epithelial cells in vitro

To study the induced differential expression of integrin αvβ3 gene in bovine uterine epithelial cells cultured in vitro, provide reference for exploring bovine uterine receptor marker protein?...

2021-07-22
【Animal Modeling】-Inhibition of Peripheral Neuron PAR2-PKA/PKCε Pathway on Pain Threshold of Pain Transformation Model Rats

【Animal Modeling】-Inhibition of Peripheral Neuron PAR2-PKA/PKCε Pathway on Pain Threshold of Pain Transformation Model Rats

To explore the role of peripheral neuroprotease-activated receptor 2-protein kinase A/protein kinase Cε (PAR2-PKA/PKCε) pathway in pain changes and possible solutions for simultaneous intervention in acute and chronic pain...

2021-07-22
【Animal Modeling】-Cysteinyl leukotriene receptor antagonist reduces the global cerebral ischemia-reperfusion injury of Mongolian gerbils by down-regulating autophagy

【Animal Modeling】-Cysteinyl leukotriene receptor antagonist reduces the global cerebral ischemia-reperfusion injury of Mongolian gerbils by down-regulating autophagy

To study the protective effect and mechanism of cysteinyl leukotriene receptor antagonist (Plukast, HAMI3379) on global cerebral ischemia-reperfusion injury in gerbils...

2021-07-22
Fufang Zhenzhu Tiaozhi Capsules regulates MEKK2-Wnt coupling and antagonizes β-catenin ubiquitination to improve glucocorticoid osteoporosis in rats

Fufang Zhenzhu Tiaozhi Capsules regulates MEKK2-Wnt coupling and antagonizes β-catenin ubiquitination to improve glucocorticoid osteoporosis in rats

To study the regulatory effects of mitogen-activated protein kinase kinase kinase 2 (MEKK2)-Wnt coupling and Pearlia Odycapsule (FTZ) intervention FTZ is a compound that antagonizes β-catenin ubiquitination and changes in bone mass. Cells that affect...

2021-07-22