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【Animal modeling】-Effect of fibrinolytic system on podocyte injury in rats with membranous nephropathy

【Animal modeling】-Effect of fibrinolytic system on podocyte injury in rats with membranous nephropathy

To investigate the importance of early prevention of fibrinolytic disorder in preventing the progression of MN...

2023-12-18
【Animal Modeling】-The role of cAMP/CREB/BDNF signaling pathway in vortioxetine against depression-like behavior in mice

【Animal Modeling】-The role of cAMP/CREB/BDNF signaling pathway in vortioxetine against depression-like behavior in mice

To study the effect of vortioxetine, a novel antidepressant, on cyclic adenosine monophosphate/cyclic adenosine monophosphate response element binding protein/brain-derived neurotrophic factor (cAMP/CREB/BDNF) signal transduction pathway...

2023-12-16
【Animal Modeling】-Effect of Metformin on Learning and Memory Ability in Mice Aging

【Animal Modeling】-Effect of Metformin on Learning and Memory Ability in Mice Aging

To explore the effect and possible mechanism of metformin supplementation on the learning and memory ability of mice during the aging process of D-galactose-induced mice...

2023-12-16
【Animal Modeling】-Establishment and evaluation of a rat model of acute lung injury induced by smoke inhalation from ship fires

【Animal Modeling】-Establishment and evaluation of a rat model of acute lung injury induced by smoke inhalation from ship fires

To establish a temperature-controllable rat model of acute lung injury induced by ship fire smoke inhalation using various composite materials as combustion materials...

2023-12-15
[Animal modeling] - Establishment of rat models of acute and chronic salpingitis infertility caused by Staphylococcus aureus

[Animal modeling] - Establishment of rat models of acute and chronic salpingitis infertility caused by Staphylococcus aureus

To establish acute and chronic salpingitis infertility models in rats by using Staphylococcus aureus...

2023-12-15
【Animal modeling】-New polycitric acid filler material induces soft tissue regeneration after rat skull defect

【Animal modeling】-New polycitric acid filler material induces soft tissue regeneration after rat skull defect

To evaluate the ability of two novel polycitric acid degradable biomaterials to induce soft tissue regeneration after calvarial defect in rats...

2023-12-14
【Animal modeling】-Study on coagulation function of rat sepsis model

【Animal modeling】-Study on coagulation function of rat sepsis model

To investigate the changes of coagulation function in a rat model of sepsis induced by cecal ligation and puncture...

2023-12-14
【Animal modeling】-Dynamic comparative study of blood and urine biochemistry between two modeling methods for kidney stones

【Animal modeling】-Dynamic comparative study of blood and urine biochemistry between two modeling methods for kidney stones

To construct two models of renal calculi in rats, and to provide support for the exploration of the etiology of nephrolithiasis...

2023-12-14
【Animal modeling】-Effect of subsequent treatment of tannin cross-linking on bovine jugular vein blood vessels

【Animal modeling】-Effect of subsequent treatment of tannin cross-linking on bovine jugular vein blood vessels

To observe the effects of tannin fixation and subsequent treatment on improving the stability of tannin cross-linked bovine jugular vein storage solution, as well as on the thermal stability of blood vessels, anti-calcification ability, biomechanical...

2023-12-14
【Animal Modeling】-Experimental study of cabozantinib in blocking Listeria monocytogenes infection in mice

【Animal Modeling】-Experimental study of cabozantinib in blocking Listeria monocytogenes infection in mice

To investigate the possibility of cabozantinib, a c-Met receptor tyrosine kinase inhibitor, as a novel drug against Listeria monocytogenes infection...

2023-12-14
【Animal Modeling】-Comparison of the effects of restraint and isoflurane anesthesia on the HPA axis of heart rate variability in rats

【Animal Modeling】-Comparison of the effects of restraint and isoflurane anesthesia on the HPA axis of heart rate variability in rats

To observe the changes of heart rate variability in rats under restraint fixation and isoflurane (flow: 0.8L, concentration: 1.5%) anesthesia; and compare the effects of restraint intervention and isoflurane anesthesia on rats by 30min per day for 9...

2023-12-14
【Animal Modeling】-Analysis of the application of asthma animal model based on data mining

【Animal Modeling】-Analysis of the application of asthma animal model based on data mining

To analyze the modeling elements of asthma animal models, and to provide methodological reference for improving the success rate of modeling and evaluating the tested drugs effectively...

2023-12-14
【Animal Modeling】-Application of Micro-arc Oxidation and Alkali Treatment Technology in Repairing Rabbit Skull Defect with Porous Tantalum

【Animal Modeling】-Application of Micro-arc Oxidation and Alkali Treatment Technology in Repairing Rabbit Skull Defect with Porous Tantalum

To observe the effects of micro-arc oxidation and alkali treatment on the surface properties, biocompatibility and osteogenic ability of porous tantalum...

2023-12-14
[Animal modeling] Reproduction and identification of sick sinus syndrome disease model constructed by miR-5572 transgenic mice

[Animal modeling] Reproduction and identification of sick sinus syndrome disease model constructed by miR-5572 transgenic mice

To investigate the feasibility of constructing sick sinus syndrome disease model in miR-5572 transgenic mice...

2023-12-14
【Animal Model】-Continuous 5-day REM sleep deprivation induces delayed-onset depression-like behavior in mice

【Animal Model】-Continuous 5-day REM sleep deprivation induces delayed-onset depression-like behavior in mice

To investigate the effect of continuous long-term rapid eye movement sleep deprivation (5 d) on depression-like behavior and the level of amygdala monoamine oxidase A in C57BL/6J mice...

2023-12-14
[Animal modeling] - Characteristics of changes in articular cartilage and subchondral bone in different animal models of osteoarthritis

[Animal modeling] - Characteristics of changes in articular cartilage and subchondral bone in different animal models of osteoarthritis

To investigate the pathological changes of subchondral bone and articular cartilage in different animal models of osteoarthritis...

2023-12-13