[Animal modeling] - Transcriptome analysis of colon tissue in IBD mice under the intervention of mesalazine

To detect the changes of gene expression in colon tissue of mice with inflammatory bowel disease (IBD) by transcriptome sequencing, and to improve the understanding of the molecular mechanism of mesalazine in the treatment of IBD...

2022-12-02

[Animal modeling] - Study on the effect and mechanism of Bushen Yiqi Huayu Granule on angiogenesis in ovariectomized osteoporosis model rats

Based on TLRs/NF- κ Study on the Effect of Bushen Yiqi Huayu Granule on Angiogenesis in Osteoporosis Rats by B Signal Pathway...

2022-12-02

[Animal modeling] - Based on autophagy, explore the effect of fentanyl combined with propofol on myocardial ischemia-reperfusion injury in rats

To investigate the effect of fentanyl combined with propofol on myocardial ischemia-reperfusion injury in rats based on autophagy...

2022-12-02

[Animal modeling] - The regulatory effect of curcumin and/or aerobic exercise on intestinal function in rats with dyslipidemia

To investigate the effects of curcumin and/or aerobic exercise on intestinal function in dyslipidemic rats...

2022-12-02

[Animal modeling] - Effect of macrophage MED1 deletion on blood glucose level and insulin resistance in mice

To study the role of macrophage MED1 in the regulation of insulin resistance...

2022-12-02

[Animal modeling] - Effect of compound microecological preparation on intestinal immune function of mice

To study the effect of compound microecological preparation on intestinal mucosal immune function in mice...

2022-12-02

[Animal modeling] - Protective effect of Dahuang Mudan decoction on liver injury in rats with acute pancreatitis

To investigate the protective effect of Dahuang Mudan decoction on liver injury in rats with acute pancreatitis...

2022-12-02

[Animal modeling] Study on the effect of Siwu Mixture on primary dysmenorrhea model mice induced by oxytocin

To study the effect of Siwu mixture on primary dysmenorrhea in mice and its possible mechanism...

2022-12-02

[Animal modeling] - Study on the influence and mechanism of different styles of music on the behavior of CUMS depression rats

To establish a depression model of SD rats by chronic mild unpredictable stimulation, and to explore the effects and mechanisms of different styles of music in improving depression like behavior in SD rats...

2022-12-02

[Animal modeling] - Study on the mechanism of Herba Siegesbeckiae Tongshuan Capsule in alleviating cognitive function damage in rats with chronic cerebral ischemia

To study the effect of Siegesbeck Tongshuan capsule on the rat model of chronic cerebral ischemia and blood brain barrier...

2022-12-02

[Animal modeling] - Based on the rat OVX model, study the effect of estrogen deficiency on the degeneration of endplate chondrocytes

To investigate the effect of estrogen deficiency on the degeneration of endplate chondrocytes...

2022-12-02

[Animal modeling] - Improvement and evaluation of conditions of rat model of myocardial hypertrophy induced by isoproterenol based on implantable osmotic pump

Myocardial hypertrophy is a slowly developing and effective compensatory function, an adaptive response to hemodynamics or myocardial injury, and an independent risk factor leading to heart failure....

2022-12-01

[Animal modeling] - Effect of arginine vasopressin 1b receptor knockout on anxiety and social behavior of female rats

to investigate the effects of arginine vasopressin 1b receptor gene knockout on plasma corticosterone content, anxiety and social behavior in female rats...

2022-12-01

[Animal modeling] - Effect of quercetin on pulmonary fibrosis in rats and its related mechanism

To investigate the effects of quercetin on interstitial transformation, inflammation and NOX4-P62 signal pathway in lung tissue of rats with pulmonary fibrosis, and to provide experimental basis for further elucidating the mechanism of quercetin on p...

2022-12-01

[Animal modeling] - The improvement of reeling water on the level of oxidative stress in aged rats

To investigate the effect of reeling water on oxidative stress in aged rats...

2022-12-01

[Animal modeling] - miR-214 protects neurons from injury after propofol anesthesia in rats

To investigate the protective effect of miR-214 on propofol induced neuronal injury and its biological mechanism...

2022-12-01