【Animal modeling】-Effect of metformin and aerobic exercise on vascular oxidative stress in type 2 diabetic rats

To evaluate the effects of metformin, aerobic exercise and the combined intervention of metformin and aerobic exercise on vascular oxidative stress in type 2 diabetic rats...

2022-12-12

[Animal modeling] Effect of single and multiple administration of Wuji Pill on pharmacokinetics in rats with irritable bowel syndrome

To determine the blood concentration of 10 active ingredients in Wuji pills at different time points after single and multiple oral administration, and compare their pharmacokinetic characteristics in normal rats and chronic visceral hypersensitive i...

2022-12-09

[Animal modeling] - Effect of Epimedium tribulus complex on sexual function and sperm vitality in rats

To study the effects of Epimedium Tribulus complex on sexual function and sperm motility in rats...

2022-12-09

[Animal modeling] - Neuroprotective effect and mechanism of Dendrobium nobile on MPTP induced PD mice

to investigate the neuroprotective effect of dendrobium nobile extract on parkinson\'s disease model induced by 1-methylv-4-phenyl-1,2,3,6-tetrahydropyridine in mice...

2022-12-09

[Animal modeling] - The improvement effect of Baixiangdan capsule on premenstrual anxiety caused by ovariectomy in rats

To compare the intervention effects of Baixiangdan capsule (BXD), 5-HT3R specific agonist and its antagonist, and cannabinoid receptor 1 (CB1R) specific agonist and its antagonist on premenstrual dysphoria and anxiety rats through a series of behavio...

2022-12-09

[Animal modeling] - Observation on the anesthetic effect of different doses of Zoletil combined with Serazine hydrochloride on C57BL/6J mice

C57BL/6J mice were anesthetized with different doses of Zoletil combined with Cyperazine hydrochloride to observe the anesthesia related time of mice under different anesthetic doses, so as to provide reference for various mouse operations and relate...

2022-12-08

[Animal modeling]- Effect of low expression of lipoic acid synthase on antioxidant capacity of mice

To establish a genetically modified mouse with low expression of lipoic acid synthase gene and detect its antioxidant capacity...

2022-12-08

[Animal modeling] - Trifolium tea herb mediation I κ B- α Effect of phosphorylation on liver fibrosis induced by CCl4 in rats

To explore the effect of Camellia trifoliata L κ B- α And its phosphorylation down regulates the signal pathway of nuclear transcription factor to alleviate carbon tetrachloride induced liver fibrosis in rats...

2022-12-08

[Animal modeling] Effect of low expression of lipoic acid synthase on antioxidant capacity of mice

To establish a genetically modified mouse with low expression of lipoic acid synthase gene and detect its antioxidant capacity...

2022-12-08

[Animal modeling] - Based on 16S rRNA sequencing, analyze the effects of two reoviruses on intestinal flora of mice

To investigate the effects of T1L and NBV reovirus on intestinal flora in mice...

2022-12-08

[Animal modeling] Effect of low expression of lipoic acid synthase on antioxidant capacity of mice

To establish a genetically modified mouse with low expression of lipoic acid synthase gene and detect its antioxidant capacity...

2022-12-07

[Animal modeling] - Effect of ginkgo honey ring oral solution on angiogenesis of myocardial microvascular endothelial cells in rats

To observe the effects of Ginkgo honey ring oral solution (Yinmi for short) on the proliferation, migration, cell tubule formation and the expression of VEGF (vascular endothelial growth factor) and CD31 (platelet endothelial cell adhesion molecule) ...

2022-12-07

[Animal modeling] - Effect of membrane cells on granulosa cells injured by chemotherapy and intervention of Zuogui Pill containing serum

To investigate the effect of membrane cells on granulosa cells injured by chemotherapy and the intervention of Zuogui Pill containing serum...

2022-12-07

[Animal modeling] - Effect of Jiayankangtai Granule on immune related cytokines in rats with autoimmune thyroiditis

To investigate the effect of Jiayankangtai Granule on immune related cytokines in rats with autoimmune thyroiditis, and explore the mechanism of Jiayankangtai Granule in improving autoimmune thyroiditis...

2022-12-07

[Animal modeling] - Pancreatic kallidinogenase alleviates oxidative stress and fibrosis in rats with myocardial ischemia-reperfusion injury

To investigate the effects of pancreatic kallidinogenase on myocardial injury, oxidative stress and fibrosis in rats with myocardial ischemia reperfusion injury...

2022-12-07

[Animal modeling] - The regulatory effect of curcumin and/or aerobic exercise on intestinal function in rats with dyslipidemia

to investigate the effects of curcumin and/or aerobic exercise on intestinal function in dyslipidemic rats...

2022-12-07